Thomas Loew
YOU?
Author Swipe
View article: SARS-CoV-2 spike epitopes as a novel clinically-relevant biomarker for post-COVID syndrome 3558
SARS-CoV-2 spike epitopes as a novel clinically-relevant biomarker for post-COVID syndrome 3558 Open
Description Persistent symptoms following SARS-CoV-2 infection, known as post-COVID syndrome (PCS), severely affect patients’ quality of life. Despite its prevalence, the underlying mechanisms and reliable biomarkers remain elusive. We inv…
View article: Hypnosis as a non-pharmacological intervention for invasive medical procedures - A systematic review and meta-analytic update
Hypnosis as a non-pharmacological intervention for invasive medical procedures - A systematic review and meta-analytic update Open
Hypnosis is recognized as an effective non-pharmacological intervention for managing anxiety, pain, and physiological stress during invasive medical procedures. Despite its growing use, variability in techniques and inconsistent outcome me…
View article: Mental health implications of fracture-related infections
Mental health implications of fracture-related infections Open
Aims Fracture-related infections (FRIs) are a major concern for patients and healthcare systems, yet their impact on mental health has been largely overlooked. This study aimed to assess the longitudinal impact of FRI on patients’ quality …
View article: Neuropsychological outcome of indoor rehabilitation in post-COVID-19 condition—results of the PoCoRe study
Neuropsychological outcome of indoor rehabilitation in post-COVID-19 condition—results of the PoCoRe study Open
Background Post COVID-19 condition (PCC) is increasingly recognized as a debilitating condition characterized by persistent symptoms following SARS-CoV-2 infection. Neuropsychological deficits, including cognitive impairments and fatigue, …
View article: Managing more than bones: the psychological impact of a recurrent fracture-related infection
Managing more than bones: the psychological impact of a recurrent fracture-related infection Open
Aims Fracture-related infections (FRIs) are a devastating complication of fracture management. However, the impact of FRIs on mental health remains understudied. The aim of this study was a longitudinal evaluation of patients’ psychologica…
View article: A multilocus genetic risk score for obesity: Association with BMI and metabolic alterations in a cohort with severe obesity
A multilocus genetic risk score for obesity: Association with BMI and metabolic alterations in a cohort with severe obesity Open
Genome wide association studies have identified numerous single nucleotide polymorphisms (SNPs) associated with obesity, yet effect sizes of individual SNPs are small. Therefore, the aim of our study was to investigate whether a genetic ri…
View article: Neurophysiological signatures of sensory-processing sensitivity
Neurophysiological signatures of sensory-processing sensitivity Open
Background Sensory processing sensitivity is mainly captured based on questionnaires and it’s neurophysiological basis is largely unknown. As hitherto no electroencephalography (EEG) study has been carried out, the aim of this work was to …
View article: Sensory-Processing Sensitivity Is Associated with Increased Neural Entropy
Sensory-Processing Sensitivity Is Associated with Increased Neural Entropy Open
Background: This study aimed at answering the following research questions: (1) Does the self-reported level of sensory-processing sensitivity (SPS) correlate with complexity, or criticality features of the electroencephalogram (EEG)? (2) …
View article: Improvement of obstructive sleep apnea does not rescue left atrial enlargement in obese participants of a multimodal weight reduction program
Improvement of obstructive sleep apnea does not rescue left atrial enlargement in obese participants of a multimodal weight reduction program Open
The aim of our study was to investigate the effect of obstructive sleep apnea (OSA) and its weight loss related improvement on left atrial (LA) area in individuals with severe obesity participating in a multimodal weight reduction (WR) pro…
View article: IgG4 serum levels are not elevated in cases of Post-COVID syndrome
IgG4 serum levels are not elevated in cases of Post-COVID syndrome Open
Recently, unexpectedly high virus-specific IgG4 levels were reported after more than two mRNA vaccinations. Class switch towards IgG4 occurs after long-term antigen exposure, downregulates immune responses and is associated with several au…
View article: First results from post-COVID inpatient rehabilitation
First results from post-COVID inpatient rehabilitation Open
Background COVID-19 is associated with various symptoms and psychological involvement in the long term. In view of the multifactorial triggering and maintenance of the post-COVID syndrome, a multimodal therapy with somatomedical and psycho…
View article: A Comprehensive Report of German Nationwide Inpatient Data on the Post-COVID-19 Syndrome Including Annual Direct Healthcare Costs
A Comprehensive Report of German Nationwide Inpatient Data on the Post-COVID-19 Syndrome Including Annual Direct Healthcare Costs Open
Background: The aim of this study was to provide a comprehensive overview of German nationwide data including (i) the number of hospitalized Post-COVID Syndrome (PCS) cases including in-hospital mortality rates and intensive care unit trea…
View article: Effect of functional relaxation on the quality of life in patients with periprosthetic joint infection: Protocol for a randomised controlled trial
Effect of functional relaxation on the quality of life in patients with periprosthetic joint infection: Protocol for a randomised controlled trial Open
Introduction Periprosthetic joint infection (PJI) is a devastating complication in orthopaedic and trauma surgery, which puts a high burden on the patients involving recurrent hospitalisation, prolonged courses of antibiotic medication, se…
View article: Gender differences in cardiometabolic health and disease in a cross-sectional observational obesity study
Gender differences in cardiometabolic health and disease in a cross-sectional observational obesity study Open
Background Beyond the degree of adiposity, the pattern of fat distribution has a profound influence on cardiometabolic risk. It is unclear if sex differences in body fat distribution can potentially explain any sex differences in the preva…
View article: Low Adherence to Pneumococcal Vaccination in Lung Cancer Patients in a Tertiary Care University Hospital in Southern Germany
Low Adherence to Pneumococcal Vaccination in Lung Cancer Patients in a Tertiary Care University Hospital in Southern Germany Open
Introduction: The aim of this study was to investigate the adherence to vaccinations, especially pneumococcal vaccinations, in lung cancer patients. Methods: the study was performed at the University Hospital Regensburg, Germany. All patie…
View article: Dual guidance structure for evaluation of patients with unclear diagnosis in centers for rare diseases (ZSE-DUO): study protocol for a controlled multi-center cohort study
Dual guidance structure for evaluation of patients with unclear diagnosis in centers for rare diseases (ZSE-DUO): study protocol for a controlled multi-center cohort study Open
Background In individuals suffering from a rare disease the diagnostic process and the confirmation of a final diagnosis often extends over many years. Factors contributing to delayed diagnosis include health care professionals' limited kn…
View article: Hemophagocytic Lymphohistiocytosis Syndrome Secondary to Disseminated Histoplasmosis in a Presumably Immunocompetent Adolescent: A Novel Case
Hemophagocytic Lymphohistiocytosis Syndrome Secondary to Disseminated Histoplasmosis in a Presumably Immunocompetent Adolescent: A Novel Case Open
Hemophagocytic Lymphohistiocytosis Syndrome Secondary to Disseminated Histoplasmosis in a Presumably Immunocompetent Adolescent: A Novel Case
View article: Short Report: Saturation Rate after Vaccination against COVID-19
Short Report: Saturation Rate after Vaccination against COVID-19 Open
Introduction: Cormirnaty® was the first available vaccine in Europe that contains mRNA encoding the spike protein of SARS-CoV2. An enormous peptide commonality and thus molecular mimicry between SARS-CoV2 spike protein and human proteins c…
View article: The health economic potential of harnessing placebos in treatment of ADHD
The health economic potential of harnessing placebos in treatment of ADHD Open
Introduction Placebo research investigated the underlying mechanisms of placebo effects, but they are rarely used to optimize treatments. Ethical and legal concerns have been raised, but research demonstrated that placebo mechanisms can be…
View article: A Multimodal Stress-Prevention Program Supplemented by Telephone-Coaching Sessions to Reduce Perceived Stress among German Farmers: Results from a Randomized Controlled Trial
A Multimodal Stress-Prevention Program Supplemented by Telephone-Coaching Sessions to Reduce Perceived Stress among German Farmers: Results from a Randomized Controlled Trial Open
This study compared the effectiveness of a 12-day stress-prevention program (SGS) supplemented by individualized, structured, four-session telephone-coaching to that of an SGS without telephone-coaching in entrepreneurs from the green prof…
View article: Why are some cases not on track? An item analysis of the Assessment for Signal Cases during inpatient psychotherapy
Why are some cases not on track? An item analysis of the Assessment for Signal Cases during inpatient psychotherapy Open
Within the Routine Outcome Monitoring system “OQ‐Analyst,” the questionnaire “Assessment for Signal Cases” (ASC) supports therapists in detecting potential reasons for not‐on‐track trajectories. Factor analysis and a machine learning algor…
View article: Placebo Economics: A Systematic Review About the Economic Potential of Utilizing the Placebo Effect
Placebo Economics: A Systematic Review About the Economic Potential of Utilizing the Placebo Effect Open
Background: Recent research shows that placebo mechanisms can be utilized in ethical and legal ways such as in open-label conditions, when patients know that they receive placebos, and through psychological interventions aiming to optimize…
View article: The adipo‐fibrokine activin A is associated with metabolic abnormalities and left ventricular diastolic dysfunction in obese patients
The adipo‐fibrokine activin A is associated with metabolic abnormalities and left ventricular diastolic dysfunction in obese patients Open
Aims Left ventricular diastolic dysfunction (LVDD) is common in obese subjects, and a relationship between epicardial adipose tissue (EAT), increased adipocytokines, and cardiovascular diseases has been reported. This study sought to exami…
View article: The concerns of the young protesters are justified: A statement by<i>Scientists for Future</i>concerning the protests for more climate protection
The concerns of the young protesters are justified: A statement by<i>Scientists for Future</i>concerning the protests for more climate protection Open
In March 2019, German-speaking scientists and scholars calling themselves Scientists for Future , published a statement in support of the youth protesters in Germany, Austria, and Switzerland (Fridays for Future, Klimastreik/Climate Strike…