Thomas Moen
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View article: Dissecting the genetic basis of response to salmonid alphavirus in Atlantic salmon
Dissecting the genetic basis of response to salmonid alphavirus in Atlantic salmon Open
Background The development of effective disease management strategies is crucial for the assurance of welfare and sustainability of the aquaculture industries. Pancreas disease (PD) is a major challenge faced by Atlantic salmon aquaculture…
View article: Uncovering Allele-Specific Expression Patterns Associated with Sea Lice (<em>Caligus rogercresseyi</em>) Resistance in Atlantic Salmon
Uncovering Allele-Specific Expression Patterns Associated with Sea Lice (<em>Caligus rogercresseyi</em>) Resistance in Atlantic Salmon Open
Sea lice (Caligus rogercresseyi), represents a major constraint to Atlantic salmon (Salmo salar) aquaculture, affecting both fish health and production efficiency. Genetic variation for sea lice load has been previously documented in Atlan…
View article: Dissecting the genetic basis of response to salmonid alphavirus in Atlantic salmon
Dissecting the genetic basis of response to salmonid alphavirus in Atlantic salmon Open
Background The development of effective disease management strategies is crucial for the assurance of welfare and sustainability of the aquaculture industries. Pancreas disease (PD) is a major challenge faced by Atlantic salmon aquaculture…
View article: Prioritized imputed sequence variants from multi-population GWAS improve prediction accuracy for sea lice count in Atlantic salmon (<i>Salmo salar</i>)
Prioritized imputed sequence variants from multi-population GWAS improve prediction accuracy for sea lice count in Atlantic salmon (<i>Salmo salar</i>) Open
Sea lice infestation is one of the major fish health problems during the grow-out phase in Atlantic salmon ( Salmo salar ) aquaculture. In this study, we integrated different genomic approaches, including whole-genome sequencing (WGS), gen…
View article: GWAS meta-analysis of resistance against Piscirickettsia salmonis in Atlantic salmon
GWAS meta-analysis of resistance against Piscirickettsia salmonis in Atlantic salmon Open
Salmonid rickettsial syndrome (SRS) remains as one of the most important pathogens for salmon farming. Genetic improvement has proven to be a viable alternative to reduce mortality in breeding stock. Understanding the genetic architecture …
View article: Genome‐wide association and genomic selection in aquaculture
Genome‐wide association and genomic selection in aquaculture Open
Recent advancements in genomic technologies have led to the discovery and application of DNA‐markers [e.g. single nucleotide polymorphisms (SNPs)] for the genetic improvement of several aquaculture species. The identification of specific g…
View article: Immersion challenge model for <i>Flavobacterium psychrophilum</i> infection of Atlantic salmon (<i>Salmo salar</i> L.) fry
Immersion challenge model for <i>Flavobacterium psychrophilum</i> infection of Atlantic salmon (<i>Salmo salar</i> L.) fry Open
Flavobacterium psychrophilum is the causative agent of bacterial cold‐water disease (CWBD) and rainbow trout fry syndrome (RTFS), which affect salmonids. To better understand this pathogen and its interaction with the host during infection…
View article: Bayesian genomic models boost prediction accuracy for survival to Streptococcus agalactiae infection in Nile tilapia (Oreochromus nilioticus)
Bayesian genomic models boost prediction accuracy for survival to Streptococcus agalactiae infection in Nile tilapia (Oreochromus nilioticus) Open
Background Streptococcosis is a major bacterial disease in Nile tilapia that is caused by Streptococcus agalactiae infection, and development of resistant strains of Nile tilapia represents a sustainable approach towards combating this dis…
View article: Beyond large-effect loci: large-scale GWAS reveals a mixed large-effect and polygenic architecture for age at maturity of Atlantic salmon
Beyond large-effect loci: large-scale GWAS reveals a mixed large-effect and polygenic architecture for age at maturity of Atlantic salmon Open
Background Understanding genetic architecture is essential for determining how traits will change in response to evolutionary processes such as selection, genetic drift and/or gene flow. In Atlantic salmon, age at maturity is an important …
View article: Bayesian genomic models boost prediction accuracy for resistance against<i>Streptococcus agalactiae</i>in Nile tilapia (<i>Oreochromus nilioticus</i>)
Bayesian genomic models boost prediction accuracy for resistance against<i>Streptococcus agalactiae</i>in Nile tilapia (<i>Oreochromus nilioticus</i>) Open
Streptococcosis due to Streptococcus agalactiae is a major bacterial disease in Nile tilapia, and development of the resistant genetic strains can be a sustainable approach towards combating this problematic disease. Thus, a controlled dis…
View article: Additional file 2 of Genomic regions and signaling pathways associated with indicator traits for feed efficiency in juvenile Atlantic salmon (Salmo salar)
Additional file 2 of Genomic regions and signaling pathways associated with indicator traits for feed efficiency in juvenile Atlantic salmon (Salmo salar) Open
Additional file 2: Table S2. An overview of all enriched KEGG pathways associated with atom % 13C (ALC) and atom % 15N (ALN) in the liver.
View article: Additional file 1 of Genomic regions and signaling pathways associated with indicator traits for feed efficiency in juvenile Atlantic salmon (Salmo salar)
Additional file 1 of Genomic regions and signaling pathways associated with indicator traits for feed efficiency in juvenile Atlantic salmon (Salmo salar) Open
Additional file 1: Table S1. An overview of all trait-associated genes (TAG) with atom % 13C (ALC) and atom % 15N (ALN) in the liver.
View article: Additional file 1 of Beyond large-effect loci: large-scale GWAS reveals a mixed large-effect and polygenic architecture for age at maturity of Atlantic salmon
Additional file 1 of Beyond large-effect loci: large-scale GWAS reveals a mixed large-effect and polygenic architecture for age at maturity of Atlantic salmon Open
Additional file 1: Table S1. Mean discordance between imputed and actual genotypes per chromosome. Table S2. List of the 120 candidate genes tagged by the 116 significant SNPs identified with conditional and joint analysis. The P-value ind…
View article: The potential for evolution of resistance to Gyrodactylus salaris in Norwegian Atlantic salmon
The potential for evolution of resistance to Gyrodactylus salaris in Norwegian Atlantic salmon Open
Karlsson, S., Bolstad, G.H., Hansen, H., Jansen, P.A., Moen, T. and Noble, L.R. 2020. The potential for evolution of resistance to Gyrodactylus salaris in Norwegian Atlantic salmon. NINA Report 1812. Norwegian Institute for Nature Research…
View article: Genomic and functional gene studies suggest a key role of beta-carotene oxygenase 1 like (bco1l) gene in salmon flesh color
Genomic and functional gene studies suggest a key role of beta-carotene oxygenase 1 like (bco1l) gene in salmon flesh color Open
Red coloration of muscle tissue (flesh) is a unique trait in several salmonid genera, including Atlantic salmon. The color results from dietary carotenoids deposited in the flesh, whereas the color intensity is affected both by diet and ge…
View article: Publisher Correction: Sex-dependent dominance maintains migration supergene in rainbow trout
Publisher Correction: Sex-dependent dominance maintains migration supergene in rainbow trout Open
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View article: Genomic and functional gene studies suggest a key role of <i>beta-carotene oxygenase 1 like (bco1l)</i> gene in salmon flesh color
Genomic and functional gene studies suggest a key role of <i>beta-carotene oxygenase 1 like (bco1l)</i> gene in salmon flesh color Open
Red coloration of muscle tissue (flesh) is a unique trait in several salmonid genera, including Atlantic salmon. The color results from dietary carotenoids deposited in the flesh, whereas the color intensity is affected both by diet and ge…
View article: Sex-dependent dominance maintains migration supergene in rainbow trout
Sex-dependent dominance maintains migration supergene in rainbow trout Open
Traits with different fitness optima in males and females cause sexual conflict when they have a shared genetic basis. Heteromorphic sex chromosomes can resolve this conflict and protect sexually antagonistic polymorphisms but accumulate d…
View article: Lumpfish (Cyclopterus lumpus) draft genome assembly
Lumpfish (Cyclopterus lumpus) draft genome assembly Open
Lumpfish draft genome assembly of a single diploid male. The fish was wild caught off the Norwegian west coast. The sample was sequenced using Illumina short-read (2x250 bp) and Oxford Nanopore long-read technology. The genome was assemble…
View article: A New Single Nucleotide Polymorphism Database for Rainbow Trout Generated Through Whole Genome Resequencing
A New Single Nucleotide Polymorphism Database for Rainbow Trout Generated Through Whole Genome Resequencing Open
Single-nucleotide polymorphisms (SNPs) are highly abundant markers, which are broadly distributed in animal genomes. For rainbow trout (Oncorhynchus mykiss), SNP discovery has been previously done through sequencing of restriction-site ass…
View article: Genome-Wide Association Study for Identifying Loci that Affect Fillet Yield, Carcass, and Body Weight Traits in Rainbow Trout (Oncorhynchus mykiss)
Genome-Wide Association Study for Identifying Loci that Affect Fillet Yield, Carcass, and Body Weight Traits in Rainbow Trout (Oncorhynchus mykiss) Open
Fillet yield (FY, %) is an economically-important trait in rainbow trout aquaculture that affects production efficiency. Despite that, FY has received little attention in breeding programs because it is difficult to measure on a large numb…
View article: The Atlantic salmon genome provides insights into rediploidization
The Atlantic salmon genome provides insights into rediploidization Open
The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique opportunities to learn about the evolutionary fate of a duplicated v…
View article: Epithelial Cadherin Determines Resistance to Infectious Pancreatic Necrosis Virus in Atlantic Salmon
Epithelial Cadherin Determines Resistance to Infectious Pancreatic Necrosis Virus in Atlantic Salmon Open
Infectious pancreatic necrosis virus (IPNV) is the cause of one of the most prevalent diseases in farmed Atlantic salmon (Salmo salar). A quantitative trait locus (QTL) has been found to be responsible for most of the genetic variation in …