Thomas Moennig
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View article: PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity
PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity Open
The conserved multiple PDZ-domain containing protein PATJ stabilizes the Crumbs-Pals1 complex to regulate apical-basal polarity and tight junction formation in epithelial cells. However, the molecular mechanism of PATJ’s function in these …