Thomas Mouillot
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View article: Management of patients with type 2 diabetes and MASLD: An overview and joint statement
Management of patients with type 2 diabetes and MASLD: An overview and joint statement Open
Type 2 diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD) are two highly prevalent diseases with rapidly growing incidences worldwide. They are frequently associated due to their shared pathophysiology and …
View article: Scientific Opinion of the French Agency for Food, Environmental and Occupational Health & Safety on Updating the State of the Evidence on the Prevention of Neural Tube Defects through vitamin B9 intake
Scientific Opinion of the French Agency for Food, Environmental and Occupational Health & Safety on Updating the State of the Evidence on the Prevention of Neural Tube Defects through vitamin B9 intake Open
Following a request from the French Directorate General for Health, ANSES was asked to deliver a scientific opinion on the state of the evidence on the prevention of neural tube defects (NTDs) by increasing vitamin B9 intake. The opinion e…
View article: Scientific Opinion of the French Agency for Food, Environmental and Occupational Health & Safety on the establishment of dietary guidelines for people following a diet that excludes some or all foods of animal origin (vegetarians)
Scientific Opinion of the French Agency for Food, Environmental and Occupational Health & Safety on the establishment of dietary guidelines for people following a diet that excludes some or all foods of animal origin (vegetarians) Open
This document presents the opinion of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES), established from the work of its Working Group on Vegetarian diets and validated by its Expert Committee on Human Nut…
View article: Non-invasive tests for fibrotic MASH for reducing screen failure in therapeutic trials
Non-invasive tests for fibrotic MASH for reducing screen failure in therapeutic trials Open
Drug development in metabolic dysfunction-associated steatohepatitis (MASH) is hampered by a high screen failure rate, one of the main reasons being the absence of MASH and significant fibrosis (fibrotic MASH) on the baseline liver biopsy,…
View article: Abstracts
Abstracts Open
Meeting abstract.
View article: French guidelines on <scp>TIPS</scp>: Indications and modalities
French guidelines on <span>TIPS</span>: Indications and modalities Open
Transjugular intrahepatic portosystemic shunt (TIPS) has become essential in the treatment or prevention of portal hypertension‐related complications. In the early 1990s, the primary indication was refractory bleeding. It is now proposed f…
View article: Recipient age influences survival after liver transplant: Results of the French national cohort 2007–2017
Recipient age influences survival after liver transplant: Results of the French national cohort 2007–2017 Open
Background In recent years, age at liver transplantation (LT) has markedly increased. In the context of organ shortage, we investigated the impact of recipient age on post‐transplantation mortality. Methods All adult patients who received …
View article: Prolonged latency of the Gustatory Evoked Potentials for sucrose solution in subjects living with obesity compared with normal-weight subjects
Prolonged latency of the Gustatory Evoked Potentials for sucrose solution in subjects living with obesity compared with normal-weight subjects Open
Objectives A difference in cortical treatment of taste information could alter food intake promoting the development of obesity. The main purpose was to compare, in subjects living with obesity (OB) and normal-weight subjects (NW), the cha…
View article: Hypothalamic Glucose Hypersensitivity-Induced Insulin Secretion in the Obese Zücker Rat Is Reversed by Central Ghrelin Treatment
Hypothalamic Glucose Hypersensitivity-Induced Insulin Secretion in the Obese Zücker Rat Is Reversed by Central Ghrelin Treatment Open
Aims: Part of hypothalamic (mediobasal hypothalamus [MBH]) neurons detect changes in blood glucose levels that in turn coordinate the vagal control of insulin secretion. This control cascade requires the production of mitocho…
View article: Taste of Fat and Obesity: Different Hypotheses and Our Point of View
Taste of Fat and Obesity: Different Hypotheses and Our Point of View Open
Obesity results from a temporary or prolonged positive energy balance due to an alteration in the homeostatic feedback of energy balance. Food, with its discriminative and hedonic qualities, is a key element of reward-based energy intake. …
View article: Perception des acides gras et potentiels évoqués gustatifs : application dans l’obésité
Perception des acides gras et potentiels évoqués gustatifs : application dans l’obésité Open
View article: Safety, Efficacy, and Outcomes of N-Butyl Cyanoacrylate Glue Injection through the Endoscopic or Radiologic Route for Variceal Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis
Safety, Efficacy, and Outcomes of N-Butyl Cyanoacrylate Glue Injection through the Endoscopic or Radiologic Route for Variceal Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis Open
We performed a systematic review and meta-analysis of published studies to assess the efficacy, safety, and outcomes of N-butyl cyanoacrylate (NBCA) injection for the treatment of variceal gastrointestinal bleeding (GIB). The MEDLINE/PubMe…
View article: Efficacy, safety and outcomes of transcatheter arterial embolization with N-butyl cyanoacrylate glue for non-variceal gastrointestinal bleeding: A systematic review and meta-analysis
Efficacy, safety and outcomes of transcatheter arterial embolization with N-butyl cyanoacrylate glue for non-variceal gastrointestinal bleeding: A systematic review and meta-analysis Open
View article: Syndrome de renutrition inappropriée
Syndrome de renutrition inappropriée Open
View article: Specific Norovirus Interaction with Lewis x and Lewis a on Human Intestinal Inflammatory Mucosa during Refractory Inflammatory Bowel Disease
Specific Norovirus Interaction with Lewis x and Lewis a on Human Intestinal Inflammatory Mucosa during Refractory Inflammatory Bowel Disease Open
Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are progressive diseases affecting millions of people each year. Flare-ups during IBD result in severe mucosal alterations of the small intestine…
View article: Specific norovirus interaction with Lewis x and Lewis a on human intestinal inflammatory mucosa during refractory inflammatory bowel disease
Specific norovirus interaction with Lewis x and Lewis a on human intestinal inflammatory mucosa during refractory inflammatory bowel disease Open
Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), is related to immunological and microbial factors with the possible implication of enteric viruses. We characterize the interaction between …
View article: Nutrition and physical activity: French intergroup clinical practice guidelines for diagnosis, treatment and follow-up (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, ACHBT, AFC, SFP-APA, SFNCM, AFSOS)
Nutrition and physical activity: French intergroup clinical practice guidelines for diagnosis, treatment and follow-up (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, ACHBT, AFC, SFP-APA, SFNCM, AFSOS) Open
This document is a summary of the French intergroup guidelines regarding the nutrition and physical activity (PA) management in digestive oncology. This collaborative work was produced under the auspices of all French medical and surgical …
View article: Hemodialysis Affects Wanting and Spontaneous Intake of Protein-Rich Foods in Chronic Kidney Disease Patients
Hemodialysis Affects Wanting and Spontaneous Intake of Protein-Rich Foods in Chronic Kidney Disease Patients Open
View article: Personality types in individuals with type 1 and type 2 diabetes
Personality types in individuals with type 1 and type 2 diabetes Open
Objective The Type A personality, characterized by impatience, strong career ambition and competitiveness, is associated with greater sensitivity to external stress. Type 1 diabetes (T1D) is an auto-immune disease, which is potentially inf…
View article: Differential Cerebral Gustatory Responses to Sucrose, Aspartame, and Stevia Using Gustatory Evoked Potentials in Humans
Differential Cerebral Gustatory Responses to Sucrose, Aspartame, and Stevia Using Gustatory Evoked Potentials in Humans Open
Aspartame and Stevia are widely substituted for sugar. Little is known about cerebral activation in response to low-caloric sweeteners in comparison with high-caloric sugar, whereas these molecules lead to different metabolic effects. We a…
View article: Proof of concept: Effect of GLP-1 agonist on food hedonic responses and taste sensitivity in poor controlled type 2 diabetic patients
Proof of concept: Effect of GLP-1 agonist on food hedonic responses and taste sensitivity in poor controlled type 2 diabetic patients Open
View article: Phospholipid profiles and hepatocellular carcinoma risk and prognosis in cirrhotic patients
Phospholipid profiles and hepatocellular carcinoma risk and prognosis in cirrhotic patients Open
This study identified phospholipid profiles related to HCC risk in liver cirrhotic patients and showed for the first time the potential of some phospholipids in predicting HCC patient mortality.
View article: Hyperphagia in short bowel patients: Fat-free mass is a strong predictor
Hyperphagia in short bowel patients: Fat-free mass is a strong predictor Open
View article: Wanting and spontaneous intake for protein-rich foods immediately after hemodialysis in chronic kidney disease patients
Wanting and spontaneous intake for protein-rich foods immediately after hemodialysis in chronic kidney disease patients Open
Communication orale de 32 diapositives dans conférence organisée par la Société de Physiologie et de Biologie Intégrative.
View article: Cerebral gustatory activation in response to free fatty acids using gustatory evoked potentials in humans
Cerebral gustatory activation in response to free fatty acids using gustatory evoked potentials in humans Open
View article: Mitochondrial Dynamin-Related Protein 1 (DRP1) translocation in response to cerebral glucose is impaired in a rat model of early alteration in hypothalamic glucose sensing
Mitochondrial Dynamin-Related Protein 1 (DRP1) translocation in response to cerebral glucose is impaired in a rat model of early alteration in hypothalamic glucose sensing Open
A hypothalamic alteration of DRP1-induced fission and mROS signaling in response to glucose was observed in HGS-induced IS of rats exposed to a 3 week HFHS diet. Early hypothalamic modifications of the neuronal activity could participate i…
View article: Prognostic Impact of 3-HM Concentration in Patients with Alcoholic or Viral Cirrhosis
Prognostic Impact of 3-HM Concentration in Patients with Alcoholic or Viral Cirrhosis Open
View article: A new method to calculate external mechanical work using force-platform data in ecological situations in humans: Application to Parkinson's disease
A new method to calculate external mechanical work using force-platform data in ecological situations in humans: Application to Parkinson's disease Open
View article: Preference for Sucrose Solutions Modulates Taste Cortical Activity in Humans
Preference for Sucrose Solutions Modulates Taste Cortical Activity in Humans Open
High time resolution is required to reliably measure neuronal activity in the gustatory cortex in response to taste stimuli. Hedonic aspects of gustatory processing have never been explored using gustatory evoked potentials (GEPs), a high-…
View article: Prandial States Modify the Reactivity of the Gustatory Cortex Using Gustatory Evoked Potentials in Humans
Prandial States Modify the Reactivity of the Gustatory Cortex Using Gustatory Evoked Potentials in Humans Open
Previous functional Magnetic Resonance Imaging studies evaluated the role of satiety on cortical taste area activity and highlighted decreased activation in the orbito-frontal cortex when food was eaten until satiation. The modulation of o…