Thomas P. Forbes
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View article: Determining the effect of bismuth oxide on the microstructure and electrical response of cold‐sintered ZnO varistors
Determining the effect of bismuth oxide on the microstructure and electrical response of cold‐sintered ZnO varistors Open
Microstructure homogeneity and grain size reduction are needed to ensure the current uniformity and reliability required in metal oxide varistors for DC circuit breakers. Cold sintering (CS)–a low‐temperature digestive liquid and high‐pres…
View article: Evaluating Contaminant Effects and Blend Ratios on the Alkaline Hydrolysis of Polyester Textile Streams
Evaluating Contaminant Effects and Blend Ratios on the Alkaline Hydrolysis of Polyester Textile Streams Open
The increasing amounts of discarded textiles represent a potentially valuable resource that could be reclaimed, for example, by chemical techniques. This work underscores the significance of utilizing chemical recycling techniques for mult…
View article: Personalized medicine: a quality by design approach to printable tablet production
Personalized medicine: a quality by design approach to printable tablet production Open
On-demand personalized medicine printing enabled customizable dose and tailored taper regimen tablet production with atline verification and inline quality assurance for patient safety.
View article: A point-of-need framework for illicit drug identification with high-resolution mass spectrometry
A point-of-need framework for illicit drug identification with high-resolution mass spectrometry Open
The continually evolving drug landscape, with novel synthetic drugs and unique compositions, necessitates the need to advance technologies, data analysis methods, and data accessibility for compound detection and identification. Providing …
View article: In-line Thermal Desorption and Dielectric Barrier Discharge Ionization for Rapid Mass Spectrometry Detection of Explosives
In-line Thermal Desorption and Dielectric Barrier Discharge Ionization for Rapid Mass Spectrometry Detection of Explosives Open
Thermal desorption (TD) of wipe-based samples was coupled with an in-line dielectric barrier discharge ionization (DBDI) source and rugged compact time-of-flight mass spectrometer (MS) for the detection of explosives, propellants, and post…
View article: Quality by Design Considerations for Drop-on-Demand Point-of-Care Pharmaceutical Manufacturing of Precision Medicine
Quality by Design Considerations for Drop-on-Demand Point-of-Care Pharmaceutical Manufacturing of Precision Medicine Open
Distributed and point-of-care (POC) manufacturing facilities enable an agile pharmaceutical production paradigm that can respond to localized needs, providing personalized and precision medicine. These capabilities are critical for narrow …
View article: Quality by Design Considerations for Drop-on-Demand Point-of-Care Pharmaceutical Manufacturing of Precision Medicine
Quality by Design Considerations for Drop-on-Demand Point-of-Care Pharmaceutical Manufacturing of Precision Medicine Open
Distributed and point-of-care (POC) manufacturing facilities enable an agile pharmaceutical production paradigm that can respond to localized needs, providing personalized and precision medicine. These capabilities are critical for narrow …
View article: Rapid Chemical Screening of Microplastics and Nanoplastics by Thermal Desorption and Pyrolysis Mass Spectrometry with Unsupervised Fuzzy Clustering
Rapid Chemical Screening of Microplastics and Nanoplastics by Thermal Desorption and Pyrolysis Mass Spectrometry with Unsupervised Fuzzy Clustering Open
The transport and chemical identification of microplastics and nanoplastics (MNPs) are critical to the concerns over plastic accumulation in the environment. Chemically and physically transient MNP species present unique challenges for iso…
View article: Rapid chemical screening of microplastics and nanoplastics by thermal desorption and pyrolysis mass spectrometry with unsupervised fuzzy clustering
Rapid chemical screening of microplastics and nanoplastics by thermal desorption and pyrolysis mass spectrometry with unsupervised fuzzy clustering Open
The transport and chemical identification of microplastics and nanoplastics (MNPs) are critical to the concerns over plastic accumulation in the environment. Chemically and physically transient MNP species present unique challenges for iso…
View article: Rapid chemical screening of microplastics and nanoplastics by thermal desorption and pyrolysis mass spectrometry with unsupervised fuzzy clustering
Rapid chemical screening of microplastics and nanoplastics by thermal desorption and pyrolysis mass spectrometry with unsupervised fuzzy clustering Open
The transport and chemical identification of microplastics and nanoplastics (MNPs) are critical to the concerns over plastic accumulation in the environment. Transient MNP species present unique challenges for isolation and analysis due to…
View article: Unsupervised pharmaceutical polymorph identification and multicomponent particle mapping of ToF-SIMS data by non-negative matrix factorization
Unsupervised pharmaceutical polymorph identification and multicomponent particle mapping of ToF-SIMS data by non-negative matrix factorization Open
Crystal polymorphism of pharmaceutical compounds directly impacts resulting physicochemical characteristics, a critical aspect in active pharmaceutical ingredient (API) production. Tools to characterize and chemically map these polymorphs …
View article: Rapid, Presumptive Identification of Seed-Based Toxins using Direct Analysis in Real Time Mass Spectrometry (DART-MS) and its Variants
Rapid, Presumptive Identification of Seed-Based Toxins using Direct Analysis in Real Time Mass Spectrometry (DART-MS) and its Variants Open
Detection of seed-based toxins is a need for forensic chemists when suspected poisonings occur. The evidence that is found is often physically unidentifiable, as the seeds are mashed to extract the toxins. This work investigates potential …
View article: Rapid, Presumptive Identification of Seed-Based Toxins using Direct Analysis in Real Time Mass Spectrometry (DART-MS) and its Variants
Rapid, Presumptive Identification of Seed-Based Toxins using Direct Analysis in Real Time Mass Spectrometry (DART-MS) and its Variants Open
Detection of seed-based toxins is a need for forensic chemists when suspected poisonings occur. The evidence that is found is often physically unidentifiable, as the seeds are mashed to extract the toxins. This work investigates potential …
View article: Confined DART-MS for Rapid Chemical Analysis of Electronic Cigarette Aerosols and Spiked Drugs
Confined DART-MS for Rapid Chemical Analysis of Electronic Cigarette Aerosols and Spiked Drugs Open
A confined direct analysis in a real time mass spectrometry (DART-MS) system and method were developed for coupling directly with commercial electronic cigarettes for rapid analysis without sample preparation. The system consisted of a con…
View article: DART-MS Spectral Similarity of Infrared Thermally Desorbed Solid Particulate and Solution Cast Propellant Samples
DART-MS Spectral Similarity of Infrared Thermally Desorbed Solid Particulate and Solution Cast Propellant Samples Open
Security and forensic applications employ test and reference materials to develop, calibrate, and validate analytical instrumentation such as mass spectrometry for the trace detection and chemical analysis of target analytes. An emerging c…
View article: Front Cover: Inorganic oxidizer detection from propellants, pyrotechnics, and homemade explosive powders using gradient elution moving boundary electrophoresis
Front Cover: Inorganic oxidizer detection from propellants, pyrotechnics, and homemade explosive powders using gradient elution moving boundary electrophoresis Open
DOI: 10.1002/elps.202000279 The cover picture shows separation and detection of anions from inorganic-based propellants, pyrotechnics, and explosive samples by gradient elution moving boundary electrophoresis (GEMBE). The GEMBE design incl…
View article: Open port sampling interface mass spectrometry of wipe-based explosives, oxidizers, and narcotics for trace contraband detection
Open port sampling interface mass spectrometry of wipe-based explosives, oxidizers, and narcotics for trace contraband detection Open
The solid–liquid extraction capabilities of open port sampling interface mass spectrometry enabled rapid and sensitive detection of military-grade explosives, homemade explosive oxidizers, and narcotics, critical to screening applications.
View article: Forensic applications of DART-MS: A review of recent literature
Forensic applications of DART-MS: A review of recent literature Open
View article: Trace detection and chemical analysis of homemade fuel-oxidizer mixture explosives: Emerging challenges and perspectives
Trace detection and chemical analysis of homemade fuel-oxidizer mixture explosives: Emerging challenges and perspectives Open
View article: Emerging techniques for the detection of pyrotechnic residues from seized postal packages containing fireworks
Emerging techniques for the detection of pyrotechnic residues from seized postal packages containing fireworks Open
High volume screening of parcels with the aim to trace the illegal distribution and selling of fireworks using postal services is challenging. Inspection services have limited manpower and means to perform extensive visual inspection. In t…
View article: Optimization of confined direct analysis in real time mass spectrometry (DART-MS)
Optimization of confined direct analysis in real time mass spectrometry (DART-MS) Open
Developing an understanding of confined DART-MS analysis.
View article: Separation and Detection of Trace Fentanyl from Complex Mixtures Using Gradient Elution Moving Boundary Electrophoresis
Separation and Detection of Trace Fentanyl from Complex Mixtures Using Gradient Elution Moving Boundary Electrophoresis Open
The current opioid epidemic remains an ongoing challenge, exacerbated by the extreme potency of synthetic opioids (e.g., fentanyl and fentanyl analogues), leading to an increase in adulterated heroin-related deaths. The increasing prevalen…
View article: Discriminative potential of ion mobility spectrometry for the detection of fentanyl and fentanyl analogues relative to confounding environmental interferents
Discriminative potential of ion mobility spectrometry for the detection of fentanyl and fentanyl analogues relative to confounding environmental interferents Open
Receiver operating characteristic (ROC) curve framework was employed to investigate the trace detection of fentanyl and fifteen fentanyl-related compounds relative to environmental background interferents.
View article: Forensic Analysis and Differentiation of Black Powder and Black Powder Substitute Chemical Signatures by Infrared Thermal Desorption–DART-MS
Forensic Analysis and Differentiation of Black Powder and Black Powder Substitute Chemical Signatures by Infrared Thermal Desorption–DART-MS Open
The trace detection and forensic analysis of black powders and black powder substitutes, directly from wipe-based sample collections, was demonstrated using infrared thermal desorption (IRTD) coupled with direct analysis in real time mass …
View article: Detection of Nonvolatile Inorganic Oxidizer-Based Explosives from Wipe Collections by Infrared Thermal Desorption—Direct Analysis in Real Time Mass Spectrometry
Detection of Nonvolatile Inorganic Oxidizer-Based Explosives from Wipe Collections by Infrared Thermal Desorption—Direct Analysis in Real Time Mass Spectrometry Open
Infrared thermal desorption (IRTD) was coupled with direct analysis in real time mass spectrometry (DART-MS) for the detection of both inorganic and organic explosives from wipe collected samples. This platform generated discrete and rapid…
View article: Recent advances in ambient mass spectrometry of trace explosives
Recent advances in ambient mass spectrometry of trace explosives Open
This review aims to showcase and critically discuss advances in ambient mass spectrometry for the trace detection of explosives.
View article: Enhanced aerodynamic reach of vapor and aerosol sampling for real-time mass spectrometric detection using Venturi-assisted entrainment and ionization
Enhanced aerodynamic reach of vapor and aerosol sampling for real-time mass spectrometric detection using Venturi-assisted entrainment and ionization Open
View article: DART-MS analysis of inorganic explosives using high temperature thermal desorption
DART-MS analysis of inorganic explosives using high temperature thermal desorption Open
Coupling resistive heating thermal desorption and direct analysis in real time demonstrated trace mass spectrometric detection of inorganic oxidizer explosives.
View article: Broad spectrum infrared thermal desorption of wipe-based explosive and narcotic samples for trace mass spectrometric detection
Broad spectrum infrared thermal desorption of wipe-based explosive and narcotic samples for trace mass spectrometric detection Open
Implementation of infrared emission enabled rapid heating rates of wipe-collected trace analytes for efficient thermal desorption and mass spectrometric detection.
View article: Rapid analysis of trace drugs and metabolites using a thermal desorption DART-MS configuration
Rapid analysis of trace drugs and metabolites using a thermal desorption DART-MS configuration Open
The need to analyze trace narcotic samples rapidly for screening or confirmatory purposes is of increasing interest to the forensic, homeland security, and criminal justice sectors.