Thomas Beck
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View article: Brain-Derived Neurotrophic Factor Protects against Ischemic Cell Damage in Rat Hippocampus
Brain-Derived Neurotrophic Factor Protects against Ischemic Cell Damage in Rat Hippocampus Open
The neuroprotective action of brain-derived neurotrophic factor (BDNF) was evaluated in a rat model of transient forebrain ischemia. A continuous intraventricular infusion of BDNF for 7 days starting immediately before the onset of ischemi…
View article: Time Course of Hippocampal Glucose Utilization and Persistence of Parvalbumin Immunoreactive Neurons after Ibotenic Acid—Induced Lesions of the Rat Dentate Area
Time Course of Hippocampal Glucose Utilization and Persistence of Parvalbumin Immunoreactive Neurons after Ibotenic Acid—Induced Lesions of the Rat Dentate Area Open
The effects of ibotenic acid induced lesions of the dentate gyrus on hippocampal glucose utilization and parvalbumin-positive neurons were evaluated in male Wistar rats. Ibotenic acid was injected in the right dorsal dentate gyrus. Quantif…
View article: The effects of two 21-aminosteroids on overt infarct size 48 hours after middle cerebral artery occlusion in the rat
The effects of two 21-aminosteroids on overt infarct size 48 hours after middle cerebral artery occlusion in the rat Open
The lipid peroxidation inhibitors U74006F (21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]-16 alpha-methylpregna-1,4,9]-(11)-triene-3, 20-dione) and U74512E (21-[4-(3-ethylamino-2-pyridinyl)-1-piperazinyl]-16 alpha-methylpregna-…
View article: The effects of dizocilpine (MK-801), phencyclidine, and nimodipine on infarct size 48 h after middle cerebral artery occlusion in the rat
The effects of dizocilpine (MK-801), phencyclidine, and nimodipine on infarct size 48 h after middle cerebral artery occlusion in the rat Open
The effects of the calcium channel blocker nimodipine and the non-competitive NMDA-antagonists MK-801 and phencyclidine (PCP) on infarct size 48 h after occlusion of the middle cerebral artery (MCA-O) were evaluated in the rat. Nimodipine …
View article: Glucose Utilization in Rat Hippocampus after Long-Term Recovery from Ischemia
Glucose Utilization in Rat Hippocampus after Long-Term Recovery from Ischemia Open
The influence on hippocampal glucose utilization of a transient 10-min forebrain ischemia was quantified in male Wistar rats after 2 and 3 weeks as well as after 3 months by application of the [ 14 C]2-deoxyglucose technique. Ischemia was …
View article: Effects of Cerebroprotective Agents on Cerebral Blood Flow and on Postischemic Energy Metabolism in the Rat Brain
Effects of Cerebroprotective Agents on Cerebral Blood Flow and on Postischemic Energy Metabolism in the Rat Brain Open
Male Wistar rats were subjected to forebrain ischemia of 10 min duration by clamping both common carotid arteries and simultaneously lowering systemic blood pressure to 40 mm Hg by exsanguination. Recovery was achieved by removing the arte…