T.P.S. Powell
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View article: The regulation of intracellular Mg2+ in guinea‐pig heart, studied with Mg(2+)‐selective microelectrodes and fluorochromes
The regulation of intracellular Mg2+ in guinea‐pig heart, studied with Mg(2+)‐selective microelectrodes and fluorochromes Open
Because of the reported presence of a Na(+)−Mg2+ exchanger in guinea‐pig but not in ferret myocardium, the Mg2+ extrusion mechanism in guinea‐pig myocardium has been reinvestigated using Mg(2+)‐ and Na(+)− selective microelectrodes and the…
View article: Mitochondrial import of cytochrome c oxidase subunit VIIa in Saccharomyces cerevisiae. Identification of sequences required for mitochondrial localization in vivo.
Mitochondrial import of cytochrome c oxidase subunit VIIa in Saccharomyces cerevisiae. Identification of sequences required for mitochondrial localization in vivo. Open
Subunit VIIa of yeast cytochrome c oxidase is a small (59 amino acids) protein of the inner mitochondrial membrane that lacks a cleavable amino-terminal presequence. To identify regions within this polypeptide that are essential for its im…
View article: A quantitative study of the neurofibrillary tangles and the choline acetyltransferase activity in the cerebral cortex and the amygdala in Alzheimer's disease.
A quantitative study of the neurofibrillary tangles and the choline acetyltransferase activity in the cerebral cortex and the amygdala in Alzheimer's disease. Open
A quantitative study has been made of the number of neurofibrillary tangles and of the choline acetyltransferase activity in several sites in the cerebral hemispheres of eight patients who had had Alzheimer's disease. The neurofibrillary t…
View article: The dementia of Alzheimer's disease: an update.
The dementia of Alzheimer's disease: an update. Open
Matters ArisingBiopterins in arginase, dihydropteridine reductase and phenylalanine hydroxylase deficiency Sir: We have reported a child with arginase deficiency who had a disturbance of central monoamine metabolism which resembled that se…
View article: Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease.
Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease. Open
The numbers and distribution of the neurofibrillary tangles and neuritic plaques have been determined in several areas of the neocortex in brains affected by various degrees of severity of Alzheimer disease. The homotypical cortex of the "…
View article: The functional organization of the isthmo‐optic nucleus in the pigeon
The functional organization of the isthmo‐optic nucleus in the pigeon Open
1. Extracellular single unit records were taken from the isthmo‐optic nucleus of the pigeon, locating the nucleus by the antidromic field potential resulting from electrical stimulation of the isthmo‐optic tract. 2. Visual receptive fields…
View article: Projection from low‐threshold muscle afferents of hand and forearm to area 3a of baboon's cortex
Projection from low‐threshold muscle afferents of hand and forearm to area 3a of baboon's cortex Open
1. The precentral and postcentral banks of the Rolandic fissure of the arm area of the baboon's cortex have been probed to their depths with extracellular micro‐electrodes under nitrous oxide and oxygen anaesthesia, supplemented by minimal…
View article: The connexions of the amygdala
The connexions of the amygdala Open
Fetal wastage is still high in the pregnancies of patients with systemic lupus erythematosus (SLE). We examined retrospectively the cases of 38 patients with inactive SLE in whom pregnancy was either desired or had already been obtained. T…
View article: THE PROJECTION OF THE MIDLINE AND INTRALAMINAR NUCLEI OF THE THALAMUS OF THE RABBIT
THE PROJECTION OF THE MIDLINE AND INTRALAMINAR NUCLEI OF THE THALAMUS OF THE RABBIT Open
studies haveindicated that thenuclei ofthemidline andinternal medullary laminaofthethalamus together constitute a functionally distinct systemwhichmay beofconsiderable importance in themaintenance and control ofnormalcerebral activity. Sin…