Thomas Vanassche
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View article: Epidemiology of Venous Thromboembolism in Belgium: A Cohort Study
Epidemiology of Venous Thromboembolism in Belgium: A Cohort Study Open
Venous thromboembolism (VTE) is a significant contributor to global morbidity and mortality. Although management strategies and the distribution of risk factors have evolved, contemporary epidemiologic data are limited and have not been pr…
View article: Risk factors associated with gastrointestinal bleeding in patients with cardiovascular disease (INTERBLEED): a case control study
Risk factors associated with gastrointestinal bleeding in patients with cardiovascular disease (INTERBLEED): a case control study Open
Aims This study aimed to identify and quantify the importance of risk factors for gastrointestinal (GI) bleeding in patients with CV disease. Methods and results We conducted a case-control study in 9 countries in Asia, America, Europe, an…
View article: Prevalence, awareness and therapeutic control of hypertension in Belgium: an opportunistic screening of nearly 6,000 participants during the May Measurement Month campaigns 2017–23
Prevalence, awareness and therapeutic control of hypertension in Belgium: an opportunistic screening of nearly 6,000 participants during the May Measurement Month campaigns 2017–23 Open
Despite the limited representativeness of the sample, these data suggest that the 'rule of halves' for hypertension no longer holds true in Belgium and that therapeutic control of hypertension is still suboptimal.
View article: <scp>ISUOG</scp>/<scp>ESGO</scp> Consensus Statement on ultrasound‐guided biopsy in gynecological oncology
<span>ISUOG</span>/<span>ESGO</span> Consensus Statement on ultrasound‐guided biopsy in gynecological oncology Open
The International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) with the European Society of Gynaecological Oncology (ESGO) jointly developed clinically relevant and evidence‐based statements on performing ultrasound‐guided bi…
View article: Retinal vessel analysis to assess microvascular function in the healthy eye: A systematic review on the response to acute physiological and pathological stressors
Retinal vessel analysis to assess microvascular function in the healthy eye: A systematic review on the response to acute physiological and pathological stressors Open
The retina allows noninvasive in vivo assessment of the microcirculation. Autoregulation of the retinal microvasculature meets the changing requirements of local metabolic demand and maintains adequate blood flow. Analysis of the retinal v…
View article: Dual guided heparin monitoring with anti-Xa and APTT during micro-axial flow pump support for cardiogenic shock
Dual guided heparin monitoring with anti-Xa and APTT during micro-axial flow pump support for cardiogenic shock Open
Background Precise management of unfractionated heparin (UFH) is key to avoid coagulopathic complications in patients on percutaneous mechanical circulatory support (pMCS) for cardiogenic shock (CS). While the activated partial thromboplas…
View article: Corrigendum: Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure
Corrigendum: Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure Open
[This corrects the article DOI: 10.3389/fcvm.2022.1024044.].
View article: Human genetics implicate thromboembolism in the pathogenesis of long COVID in individuals of European ancestry
Human genetics implicate thromboembolism in the pathogenesis of long COVID in individuals of European ancestry Open
SARS-CoV-2 infection can result in long COVID, characterized by post-acute symptoms from multiple organs. Current hypotheses on mechanisms underlying long COVID include persistent inflammation and thromboembolism; however, compelling evide…
View article: Management of edoxaban therapy in patients undergoing emergency/urgent procedures: a subanalysis of the global, prospective, observational, multinational EMIT-AF/VTE programme
Management of edoxaban therapy in patients undergoing emergency/urgent procedures: a subanalysis of the global, prospective, observational, multinational EMIT-AF/VTE programme Open
Background Physicians are often unable to follow recommendations for preprocedural oral anticoagulant interruption before emergency/urgent (unplanned) procedures, which may lead to a higher incidence of adverse outcomes in these patients c…
View article: The current landscape of factor XI inhibitors
The current landscape of factor XI inhibitors Open
Anticoagulant therapy has always been tightly connected with bleeding risk, as two sides of the same coin. New insights in thrombosis and hemostasis prompted the development of intrinsic pathway inhibitors that promise to uncouple thrombos…
View article: Heparin monitoring in ImpellaTM-supported cardiogenic shock patients: the benefit of parallel dual testing
Heparin monitoring in ImpellaTM-supported cardiogenic shock patients: the benefit of parallel dual testing Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Fonds Wetenschappelijk Onderzoek Flanders. Background Coagulopathic complications often jeopardize the outcome of critically …
View article: Anti-Xa/APTT discrepancy in heparinized ImpellaTM-supported cardiogenic shock patients can predict mortality
Anti-Xa/APTT discrepancy in heparinized ImpellaTM-supported cardiogenic shock patients can predict mortality Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Fonds Wetenschappelijk Onderzoek Flanders. Background Meticulous management of unfractionated heparin (UFH) is important to a…
View article: Thrombophilia Testing: from Genetic Predisposition to Discrimination
Thrombophilia Testing: from Genetic Predisposition to Discrimination Open
Received: 21 December 2023 Accepted after revision: 05 March 2024 Accepted Manuscript online:09 March 2024
View article: Periprocedural Edoxaban Management and Clinical Outcomes in Patients Undergoing Transcatheter Cardiovascular Procedures in the EMIT-AF/VTE Program
Periprocedural Edoxaban Management and Clinical Outcomes in Patients Undergoing Transcatheter Cardiovascular Procedures in the EMIT-AF/VTE Program Open
Annually, 10% of patients with atrial fibrillation (AF) or venous thromboembolism (VTE) treated with non-vitamin K oral anticoagulants undergo diagnostic or therapeutic procedures. This subanalysis of the multicenter, prospective, observat…
View article: The Relevance of Arterial Blood Pressure in the Management of Glaucoma Progression: A Systematic Review
The Relevance of Arterial Blood Pressure in the Management of Glaucoma Progression: A Systematic Review Open
BACKGROUND Glaucoma is one of the leading causes of global blindness and is expected to co-occur more frequently with vascular morbidities in the upcoming years, as both are aging-related diseases. Yet, the pathogenesis of glaucoma is not …
View article: Effectiveness and safety of bempedoic acid in routine clinical practice: 1-year follow-up snapshot of the MILOS German cohort
Effectiveness and safety of bempedoic acid in routine clinical practice: 1-year follow-up snapshot of the MILOS German cohort Open
Background Low-density lipoprotein cholesterol (LDL-C) has an established role in the development of atherosclerotic cardiovascular disease. The 2019 ESC/EAS dyslipidaemia guidelines recommended more intensive treatment goals, however, man…
View article: Urinary proteomics signature of malignancy post heart transplantation is associated with mortality risk
Urinary proteomics signature of malignancy post heart transplantation is associated with mortality risk Open
Background Heart transplant recipients are at an increased risk of malignancy that has an adverse impact on outcomes. The surveillance of malignancy after heart transplantation is cumbersome and involves multidisciplinary efforts. Purpose …
View article: OC 46.1 Absolute Quantitative Proteomics for Occult Cancer Screening in Patient with Unprovoked Venous Thromboembolism: Results from the Prospective PLATO-VTE Study
OC 46.1 Absolute Quantitative Proteomics for Occult Cancer Screening in Patient with Unprovoked Venous Thromboembolism: Results from the Prospective PLATO-VTE Study Open
Background: Coagulopathy with associated bleeding and venous thromboembolism (VTE) is a major cause of early morbidity and mortality in patients with acute leukemia.However, the mechanisms leading to bleeding and VTE have not been fully el…
View article: Peptidylarginine deiminase 4 and ADAMTS13 activity in <i>Staphylococcus</i> <i>aureus</i> bacteraemia
Peptidylarginine deiminase 4 and ADAMTS13 activity in <i>Staphylococcus</i> <i>aureus</i> bacteraemia Open
Staphylococcus aureus infection is associated with increased levels of neutrophil extracellular traps (NETs) and von Willebrand factor (VWF), and with reduced activity of ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin ty…
View article: OC 06.2 Emicizumab for Acquired Hemophilia A - A Case Series
OC 06.2 Emicizumab for Acquired Hemophilia A - A Case Series Open
FVIII levels ≤0.20 IU/mL, showed a Mim8 dose dependent interference increase with the largest fold increase (2.4 to 4.5, ADVATE ® ) at low FVIII levels (0.05 IU/mL).More interference by Mim8 was observed in SHL products.As FVIII levels inc…