Thulani Maphosa
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View article: Tuberculosis preventive treatment uptake among patients initiating antiretroviral therapy in Malawi: Children left behind
Tuberculosis preventive treatment uptake among patients initiating antiretroviral therapy in Malawi: Children left behind Open
Background: Tuberculosis preventive treatment (TPT) is recommended for people living with HIV (PLHIV) to reduce the tuberculosis (TB) incidence in regions with a high prevalence of TB. We evaluated the uptake and completion of TPT among ne…
View article: Impact of an optimized care model for advanced HIV disease: a non-randomized cluster study in Malawi
Impact of an optimized care model for advanced HIV disease: a non-randomized cluster study in Malawi Open
View article: Clinical impact and cost-effectiveness of the WHO-recommended advanced HIV disease package of care
Clinical impact and cost-effectiveness of the WHO-recommended advanced HIV disease package of care Open
For the Chichewa translation of the abstract see Supplementary Materials section.
View article: HIV viral suppression after enhanced adherence counselling in children on dolutegravir-based regimens in Malawi
HIV viral suppression after enhanced adherence counselling in children on dolutegravir-based regimens in Malawi Open
Background: Viral suppression (VS) rates in children on antiretroviral therapy (ART) are lower than in adults. We described the effect of enhanced adherence counselling (EAC) on VS among children with high HIV viral load accessing dolutegr…
View article: Barriers and facilitators to implementing six monthly multi-month dispensing of antiretroviral therapy in two urban HIV clinics during the COVID-19 Era in Malawi
Barriers and facilitators to implementing six monthly multi-month dispensing of antiretroviral therapy in two urban HIV clinics during the COVID-19 Era in Malawi Open
Following the COVID-19 pandemic, the Malawi Government released a policy that promoted the scale-up of six-monthly multi-month dispensing (6-MMD) of antiretroviral therapy (ART) to people living with HIV in order to decrease congestion at …
View article: Examining teen club attendance and viral load suppression among adolescents under differentiated HIV care in Malawi: a sub-optimal scenario
Examining teen club attendance and viral load suppression among adolescents under differentiated HIV care in Malawi: a sub-optimal scenario Open
Even amongst adolescents enrolled in teen clubs, teen club attendance is low and high HIV viremia prevails. A continual focus on adolescents is needed to promote consistent teen club attendance and consistent ART adherence among the adoles…
View article: Improving HIV testing and retention among adolescents and youths: Lessons from a quasi-experimental study of the Red-Carpet Program in Malawi
Improving HIV testing and retention among adolescents and youths: Lessons from a quasi-experimental study of the Red-Carpet Program in Malawi Open
Adolescents and youth living with HIV (AYLHIV) often face significant challenges in HIV care. Elizabeth Glaser Pediatric AIDS Foundation in Malawi implemented the Red-Carpet Program (RCP) to provide fast-tracked services for AYLHIV in care…
View article: Influence of the SARS-COV2 pandemic on access to healthcare services among people living with HIV and its subsequent effects on antiretroviral therapy uptake in Malawi
Influence of the SARS-COV2 pandemic on access to healthcare services among people living with HIV and its subsequent effects on antiretroviral therapy uptake in Malawi Open
The global disruption caused by the SARS-CoV-2 pandemic profoundly affected healthcare systems, particularly impacting People Living with Human Immunodeficiency Virus (PLHIV). This study investigated the repercussions of SARS-CoV-2 infecti…
View article: Unlocking the potential: exploring the impact of dolutegravir treatment on body mass index improvement in underweight adults with HIV in Malawi
Unlocking the potential: exploring the impact of dolutegravir treatment on body mass index improvement in underweight adults with HIV in Malawi Open
View article: Enhancing SARS-CoV-2 surveillance in Malawi using telephone syndromic surveillance from July 2020 to April 2022
Enhancing SARS-CoV-2 surveillance in Malawi using telephone syndromic surveillance from July 2020 to April 2022 Open
Introduction Monitoring the SARS-CoV-2 pandemic in low-resource countries such as Malawi requires cost-effective surveillance strategies. This study explored the potential utility of phone-based syndromic surveillance in terms of its reach…
View article: Early Effects of Scaling Up Dolutegravir-Based ARV Regimens Among Children Living with HIV in Malawi
Early Effects of Scaling Up Dolutegravir-Based ARV Regimens Among Children Living with HIV in Malawi Open
View article: Understanding health systems challenges in providing Advanced HIV Disease (AHD) care in a hub and spoke model: a qualitative analysis to improve AHD care program in Malawi
Understanding health systems challenges in providing Advanced HIV Disease (AHD) care in a hub and spoke model: a qualitative analysis to improve AHD care program in Malawi Open
Background Despite tremendous progress in antiretroviral therapy (ART) and access to ART, many patients have advanced human immunodeficiency virus (HIV) disease (AHD). Patients on AHD, whether initiating ART or providing care after disenga…
View article: Factors associated with COVID-19 vaccine receipt among mobile phone users in Malawi: Findings from a national mobile-based syndromic surveillance survey, July 2021-April 2022
Factors associated with COVID-19 vaccine receipt among mobile phone users in Malawi: Findings from a national mobile-based syndromic surveillance survey, July 2021-April 2022 Open
Malawi recommended COVID-19 vaccines for adults aged ≥18 years in March 2021. We assessed factors associated with receiving COVID-19 vaccines in Malawi as part of a telephone-based syndromic surveillance survey. We conducted telephone-base…
View article: Characteristics of TPT initiation and completion among people living with HIV
Characteristics of TPT initiation and completion among people living with HIV Open
BACKGROUND: TB preventive treatment (TPT) reduces morbidity and mortality among people living with HIV (PLHIV). Despite the successful scale-up of TPT in Malawi, monitoring and evaluation have been suboptimal. We utilized the Malawi Popula…
View article: Understanding gender differences of people with HIV newly diagnosed or returning to care with advanced HIV disease in Malawi: a qualitative study
Understanding gender differences of people with HIV newly diagnosed or returning to care with advanced HIV disease in Malawi: a qualitative study Open
Background Despite tremendous progress in improving antiretroviral therapy (ART) access, advanced HIV disease (AHD) still remains a challenge globally. Reasons for delayed presentation to care and ART adherence may be affected by gender. W…
View article: Safety of Janssen Ad26.COV.S and Astra Zeneca AZD1222 COVID-19 Vaccines among Mobile Phone Users in Malawi: Findings from a National Mobile-Based Syndromic Surveillance Survey, July 2021 to December 2021
Safety of Janssen Ad26.COV.S and Astra Zeneca AZD1222 COVID-19 Vaccines among Mobile Phone Users in Malawi: Findings from a National Mobile-Based Syndromic Surveillance Survey, July 2021 to December 2021 Open
The safety profiles of the Ad26.COV2.S and AZD1222 COVID-19 vaccines have not been described in the general population in Malawi. We present self-reported adverse events (AE) following the receipt of these vaccines in Malawi as part of a n…
View article: Understanding health systems challenges in providing Advanced HIV Disease (AHD) care in a hub and spoke model: A qualitative analysis to improve AHD care program in Malawi.
Understanding health systems challenges in providing Advanced HIV Disease (AHD) care in a hub and spoke model: A qualitative analysis to improve AHD care program in Malawi. Open
Background Despite tremendous progress in improving antiretroviral therapy (ART) and access to ART, many patients have advanced HIV disease (AHD). AHD patients, whether initiating ART or representing care after disengagement, have an incre…
View article: Acceptability and usability of a paediatric HIV screening tool in high-volume outpatient settings in Malawi, perspectives from caregivers and healthcare workers
Acceptability and usability of a paediatric HIV screening tool in high-volume outpatient settings in Malawi, perspectives from caregivers and healthcare workers Open
Background Using an HIV pretest screening tool to identify children most at risk for HIV infection may be a more efficient and cost-effective approach to identify children living with HIV in resource-limited settings. These tools seek to r…
View article: Protocol to implement a syndromic surveillance survey of COVID-19 in Malawi
Protocol to implement a syndromic surveillance survey of COVID-19 in Malawi Open
View article: Isoniazid-associated pellagra during mass scale-up of tuberculosis preventive therapy: a case-control study
Isoniazid-associated pellagra during mass scale-up of tuberculosis preventive therapy: a case-control study Open
View article: Unsafe disposal of faeces and its correlates among children under three years in Eswatini
Unsafe disposal of faeces and its correlates among children under three years in Eswatini Open
Background. It has long been established that human excreta contain over 50 pathogens that are transmitted via the faecal route, yet the common practice of unsafe disposal of children's faeces still persists in developing countries. Object…
View article: Implementation of Integrated Disease Surveillance and Response (IDSR) in Swaziland
Implementation of Integrated Disease Surveillance and Response (IDSR) in Swaziland Open
Objective: To strengthen public health surveillance and monitor implementation of Integrated Disease Surveillance and Response in the Kingdom of Swaziland.Introduction: Swaziland adopted the Integrated Disease Surveillance and Response (ID…
View article: Morbidity patterns associated with seasonal influenza A/H1N1in Swaziland
Morbidity patterns associated with seasonal influenza A/H1N1in Swaziland Open
ObjectiveTo establish morbidity patterns of influenza A/H1N1 in Swaziland from 10th July to 15th August 2017.IntroductionInfluenza infection is caused by the influenza virus, a single-stranded RNA virus belonging to the Orthomyxoviridae fa…
View article: Active case-finding and enhanced data collection to identify neglected tropical diseases
Active case-finding and enhanced data collection to identify neglected tropical diseases Open
ObjectiveTo strengthen public health surveillance to monitor neglected tropical diseases (NTDs) like leprosy as a control measure to avert disabilities in the Kingdom of Swaziland.IntroductionLeprosy is a chronic infectious disease caused …
View article: Evaluating the sensitivity of a passive diarrheal disease surveillance system during a post-drought
Evaluating the sensitivity of a passive diarrheal disease surveillance system during a post-drought Open
ObjectiveTo evaluate the difference in sensitivity between passive and active diarrheal and malnutrition disease surveillance system post-drought period in SwazilandIntroductionOver the past decade Swaziland has experienced recurring droug…