Tian Jian Lu
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View article: MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis
MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis Open
Cancer metastasis is governed by physical cues at the cell‐matrix interface, with matrix stiffness, ligand density, and topography established as key determinants. Here, a fourth critical factor in cancer metastasis, the architecture of th…
View article: HMMR mediates progression of nasopharyngeal carcinoma by inhibiting FAM83D ubiquitination and activating beta-catenin signaling pathway
HMMR mediates progression of nasopharyngeal carcinoma by inhibiting FAM83D ubiquitination and activating beta-catenin signaling pathway Open
The hyaluronan-mediated motility receptor (HMMR) is widely expressed across various species and plays a crucial role in cancer progression. However, its role in nasopharyngeal carcinoma (NPC) remains unexplored. Here, we identified a novel…
View article: Stably biased gap flow between two flapping and stationary short cantilevers in close proximity
Stably biased gap flow between two flapping and stationary short cantilevers in close proximity Open
View article: Traction-regulated persistence governs durotaxis across cell types
Traction-regulated persistence governs durotaxis across cell types Open
Cell migration toward stiffer or softer environments (durotaxis) underlies processes from development to cancer metastasis, yet the underlying mechanism and its universality remain unclear. To resolve this, we investigated how traction for…
View article: Modeling the laser irradiation induced carbonate loss in dental enamel for dental caries prevention
Modeling the laser irradiation induced carbonate loss in dental enamel for dental caries prevention Open
View article: Interesting Aromaticity of Franck–Condon Excited States of Cyclo[16]Carbon
Interesting Aromaticity of Franck–Condon Excited States of Cyclo[16]Carbon Open
Inspired by the realization of cyclo[16]carbon (C 16 ) and driven by curiosity about its properties in excited states, a comprehensive theoretical study was conducted on the aromatic characteristics in the Franck–Condon states of C 16 . Th…
View article: Achieving excellent optical molecules by screening superalkali-doped cyclo[2n]carbon, M3O@C2n (M = Li, Na, and K, n = 5-10)
Achieving excellent optical molecules by screening superalkali-doped cyclo[2n]carbon, M3O@C2n (M = Li, Na, and K, n = 5-10) Open
Using cyclo[2n]carbon (C2n, n = 5-10) that have been experimentally characterized as electron acceptor and superalkali clusters M3O (M = Li, Na, and K) with excess electrons as electron source, we designed nonlinear optical (NLO) electride…
View article: WITHDRAWN: Reshaping women’s health communication: A content analysis of health education videos by Obstetrics and Gynecology KOLs on Xiaohongshu
WITHDRAWN: Reshaping women’s health communication: A content analysis of health education videos by Obstetrics and Gynecology KOLs on Xiaohongshu Open
The full text of this preprint has been withdrawn by the authors due to author disagreement with the posting of the preprint. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corr…
View article: WITHDRAWN: Reshaping women’s health communication: A content analysis of health education videos by Obstetrics and Gynecology KOLs on Xiaohongshu
WITHDRAWN: Reshaping women’s health communication: A content analysis of health education videos by Obstetrics and Gynecology KOLs on Xiaohongshu Open
Background This study investigates the communication strategies adopted by Key Opinion Leaders (KOLs) in the fields of obstetrics and gynecology to share knowledge about women’s reproductive health and examines their impacts on user engage…
View article: Obtaining (BN)4C10 with excellent optoelectronic properties by screening boron-nitrogen analogues of cyclo[18]carbon, (BN)nC(18-2n) (n = 1–9)
Obtaining (BN)4C10 with excellent optoelectronic properties by screening boron-nitrogen analogues of cyclo[18]carbon, (BN)nC(18-2n) (n = 1–9) Open
The geometric structures as well as electronic, nonlinear optical, and photophysical properties of boron-nitrogen (B-N) analogues of cyclo[18]carbon (C18), (BN)nC(18-2n) (n = 1–9), were comprehensively studied using density functional theo…
View article: Performance Enhancement of Disk-Shaped Flat Loop Heat Pipe
Performance Enhancement of Disk-Shaped Flat Loop Heat Pipe Open
View article: The Past and Present of Schizophrenia
The Past and Present of Schizophrenia Open
Schizophrenia is a severe mental disorder and one of the most challenging psychiatric diseases to treat clinically. Modern medical treatment for schizophrenia primarily relies on antipsychotic medications, but issues such as side effects a…
View article: Note about network decomposition by maximum flow
Note about network decomposition by maximum flow Open
The goal of this paper is to establish a decomposition of the network based on the maximum flow problem.
View article: Friction welding of 42CrMo medium carbon steel and 36Mn2V alloy steel: Effects of forging pressure and post-weld heat treatment on microstructure and mechanical properties
Friction welding of 42CrMo medium carbon steel and 36Mn2V alloy steel: Effects of forging pressure and post-weld heat treatment on microstructure and mechanical properties Open
42CrMo medium carbon steel and 36Mn2V alloy steel were successfully jointed using continuous drive friction welding. The effects of forging pressure and post-weld heat treatment on microstructure and mechanical properties of joints were in…
View article: Cross-scale mechanobiological regulation of cylindrical compressible liquid inclusion via coating
Cross-scale mechanobiological regulation of cylindrical compressible liquid inclusion via coating Open
The double-bag theory in modern anatomy suggests that structures with coatings are commonly found in human body at various length scales, such as osteocyte processes covered by pericellular matrix and bones covered by muscle tissue. To und…
View article: Dual‐Scale Spiral Material for Balancing High Load Bearing and Sound Absorption
Dual‐Scale Spiral Material for Balancing High Load Bearing and Sound Absorption Open
Porous materials with sound absorption and load‐bearing capabilities are in demand in engineering fields like aviation and rail transportation. However, achieving both properties simultaneously is challenging due to the trade‐off between i…
View article: Programmable and Reversible Integrin‐Mediated Cell Adhesion Reveals Hysteresis in Actin Kinetics that Alters Subsequent Mechanotransduction (Adv. Sci. 35/2023)
Programmable and Reversible Integrin‐Mediated Cell Adhesion Reveals Hysteresis in Actin Kinetics that Alters Subsequent Mechanotransduction (Adv. Sci. 35/2023) Open
Mechanotransduction Article number 2302421 reports that cyclical adhesion can alter stem cell perception of extracellular microenvironment stiffness and thereby controls their mechanosensing and fate commitment. Min Lin and co‐workers demo…
View article: Double Aromaticity of Franck-Condon Excited States of Cyclo[16]carbon
Double Aromaticity of Franck-Condon Excited States of Cyclo[16]carbon Open
Excited-state aromaticity of molecular rings is a very interesting and meaningful topic. Inspired by the recent realization of cyclo[16]carbon (C16) with double anti-aromaticity characteristics of singlet ground state (S0 state), here we d…
View article: Programmable and Reversible Integrin‐Mediated Cell Adhesion Reveals Hysteresis in Actin Kinetics that Alters Subsequent Mechanotransduction
Programmable and Reversible Integrin‐Mediated Cell Adhesion Reveals Hysteresis in Actin Kinetics that Alters Subsequent Mechanotransduction Open
Dynamically evolving adhesions between cells and extracellular matrix (ECM) transmit time‐varying signals that control cytoskeletal dynamics and cell fate. Dynamic cell adhesion and ECM stiffness regulate cellular mechanosensing cooperativ…
View article: Crashworthiness of Foam-Filled Cylindrical Sandwich Shells with Corrugated Cores
Crashworthiness of Foam-Filled Cylindrical Sandwich Shells with Corrugated Cores Open
Inspired by material hybrid design, novel hybrid sandwich shells were developed by filling a corrugated cylindrical structure with aluminum foam to achieve higher energy absorption performance. The crushing behavior of the foam-filled corr…
View article: Numerical study of heat transfer and load-bearing performances of corrugated sandwich structure with open-cell metal foam
Numerical study of heat transfer and load-bearing performances of corrugated sandwich structure with open-cell metal foam Open
Critical engineering applications require lightweight components that can effectively dissipate heat and provide sufficient load-bearing capacity. Examples of such applications include the jet blast deflector (JBD) on an aircraft carrier a…
View article: CCDC 2128752: Experimental Crystal Structure Determination
CCDC 2128752: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Deep subwavelength hybrid metamaterial for low-frequency underwater sound absorption by quasi-Helmholtz resonance
Deep subwavelength hybrid metamaterial for low-frequency underwater sound absorption by quasi-Helmholtz resonance Open
We proposed an acoustic metamaterial with deep subwavelength thickness for low-frequency underwater sound absorption. The proposed hybrid metamaterial has a perforated facesheet, a fluid-filled square honeycomb core with inside rubber coat…
View article: Programmable integrin and N-cadherin adhesive interactions modulate mechanosensing of mesenchymal stem cells by cofilin phosphorylation
Programmable integrin and N-cadherin adhesive interactions modulate mechanosensing of mesenchymal stem cells by cofilin phosphorylation Open
View article: Dynamic response of UHMWPE plates under combined shock and fragment loading
Dynamic response of UHMWPE plates under combined shock and fragment loading Open
Ultra-high molecular weight polyethylene (UHMWPE) fiber composite has been extensively used to construct lightweight protective structures against ballistic impacts, yet little is known about its performance when subjected to combined blas…
View article: Grating‐like anechoic layer for broadband underwater sound absorption
Grating‐like anechoic layer for broadband underwater sound absorption Open
To address the challenging task of effective sound absorption in the low and broad frequency band for underwater structures, we propose a novel grating‐like anechoic layer by filling rubber blocks and an air backing layer into metallic gra…
View article: Acoustic radiation force on a long cylinder, and potential sound transduction by tomato trichomes
Acoustic radiation force on a long cylinder, and potential sound transduction by tomato trichomes Open
View article: CCDC 2150888: Experimental Crystal Structure Determination
CCDC 2150888: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Directed cell migration towards softer environments
Directed cell migration towards softer environments Open
View article: Localization of elastic waves in one-dimensional detuned phononic crystals with flexoelectric effect
Localization of elastic waves in one-dimensional detuned phononic crystals with flexoelectric effect Open
Although forbidden band effect in perfectly periodic phononic crystals (PC) is very attractive, random disordered (i.e. detuning) phenomenon is inevitable in engineering processing, thus exploring the effect of detuning on the wave charact…