Tianna Grant
YOU?
Author Swipe
View article: A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling
A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling Open
Altered myeloid inflammation and lymphopenia are hallmarks of severe infections. We identified the upregulated EN-RAGE gene program in airway and blood myeloid cells from patients with acute lung injury from SARS-CoV-2 or other causes acro…
View article: A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling
A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling Open
Summary Altered myeloid inflammation and lymphopenia are hallmarks of severe infections, including SARS-CoV-2. Here, we identified a gene program, defined by correlation with EN-RAGE ( S100A12 ) gene expression, which was up-regulated in p…
View article: Nurturing diversity and inclusion in AI in Biomedicine through a virtual summer program for high school students
Nurturing diversity and inclusion in AI in Biomedicine through a virtual summer program for high school students Open
Artificial Intelligence (AI) has the power to improve our lives through a wide variety of applications, many of which fall into the healthcare space; however, a lack of diversity is contributing to limitations in how broadly AI can help pe…
View article: Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19 Open
Type I interferon autoantibodies in patients with COVID-19 are associated with poor interferon responses and increased LAIR1 abundance in leukocytes.
View article: Sex disparate gut microbiome and metabolome perturbations precede disease progression in a mouse model of Rett syndrome
Sex disparate gut microbiome and metabolome perturbations precede disease progression in a mouse model of Rett syndrome Open
Rett syndrome (RTT) is a severe regressive neurodevelopmental disorder in girls, characterized by multisystem complications including gut dysbiosis and altered metabolism. While RTT is known to be caused by mutations in the X-linked gene M…
View article: Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19
Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19 Open
Type I interferon (IFN-I) neutralizing autoantibodies have been found in some critical COVID-19 patients; however, their prevalence and longitudinal dynamics across the disease severity scale, and functional effects on circulating leukocyt…
View article: Nurturing diversity and inclusion in AI in Biomedicine through a virtual summer program for high school students
Nurturing diversity and inclusion in AI in Biomedicine through a virtual summer program for high school students Open
Artificial Intelligence (AI) has the power to improve our lives through a wide variety of applications, many of which fall into the healthcare space; however, a lack of diversity is contributing to flawed systems that perpetuate gender and…