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View article: Monkeypox virus induces ferroptosis to facilitate viral replication and promotes inflammatory responses
Monkeypox virus induces ferroptosis to facilitate viral replication and promotes inflammatory responses Open
Ferroptosis is an iron-dependent form of programmed cell death, which is characterized by iron overload and accumulation of lipid peroxidation. As a newly identified type of cell death, its involvement in poxvirus infection and pathogenesi…
View article: Long‐Lasting Protection and Dose Optimization of MPXV Polyvalent Mpox mRNA Vaccines Against Lethal Vaccinia Virus Challenge in Mice
Long‐Lasting Protection and Dose Optimization of MPXV Polyvalent Mpox mRNA Vaccines Against Lethal Vaccinia Virus Challenge in Mice Open
The outbreak of clade II monkeypox virus (MPXV) and the additional outbreak in Central Africa of clade I virus from 2023 have attracted worldwide attention. The development of a scalable and effective vaccine against the ongoing epidemic o…
View article: Polyvalent mpox mRNA vaccines elicit robust immune responses and confer potent protection against vaccinia virus
Polyvalent mpox mRNA vaccines elicit robust immune responses and confer potent protection against vaccinia virus Open
The 2022 mpox outbreak led the World Health Organization (WHO) to declare it a public health emergency of international concern (PHEIC). There is a need to develop more effective and safer mpox virus (MPXV)-specific vaccines in response to…