Tiange Wu
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View article: YY1 enhances HIF-1α stability in tumor-associated macrophages to suppress anti-tumor immunity of prostate cancer in mice
YY1 enhances HIF-1α stability in tumor-associated macrophages to suppress anti-tumor immunity of prostate cancer in mice Open
View article: Remote ischemia precondition protects against renal IRI through apoptosis associated vesicles carrying MIF protein via modulating DUSP6/JNK signaling axis
Remote ischemia precondition protects against renal IRI through apoptosis associated vesicles carrying MIF protein via modulating DUSP6/JNK signaling axis Open
View article: A unified eIF1A<sup>+</sup>luminal cells-centered hypoxic and “cold” tumor microenvironment promotes PCa progression among different subtypes
A unified eIF1A<sup>+</sup>luminal cells-centered hypoxic and “cold” tumor microenvironment promotes PCa progression among different subtypes Open
PCa is a malignancy with high heterogeneity arises from both tumor microenvironment (TME) and histological subtypes. To achieve superior clinical efficacy, it is imperative to identify unified progression drivers within such heterogeneity …
View article: Matrix Metalloproteinase-9 is associated with tumor microenvironment remodeling of bladder cancer
Matrix Metalloproteinase-9 is associated with tumor microenvironment remodeling of bladder cancer Open
View article: YY1 Enhances the Stability of HIF-1α Protein by Interacting with NUSAP1 in Macrophages within the Prostate Cancer Microenvironment
YY1 Enhances the Stability of HIF-1α Protein by Interacting with NUSAP1 in Macrophages within the Prostate Cancer Microenvironment Open
Immune checkpoint therapy for prostate cancer (PCa) has failed in clinical trials; however, the precise underlying mechanisms involved remain elusive. PCa, a classic "immune-cold” tumor, is characterized by an immunosuppressive tumor micro…
View article: MDK promotes M2 macrophage polarization to remodel the tumour microenvironment in clear cell renal cell carcinoma
MDK promotes M2 macrophage polarization to remodel the tumour microenvironment in clear cell renal cell carcinoma Open
View article: Correction: Endoplasmic reticulum stress-related genes as prognostic and immunogenic biomarkers in prostate cancer
Correction: Endoplasmic reticulum stress-related genes as prognostic and immunogenic biomarkers in prostate cancer Open
View article: Endoplasmic reticulum stress-related genes as prognostic and immunogenic biomarkers in prostate cancer
Endoplasmic reticulum stress-related genes as prognostic and immunogenic biomarkers in prostate cancer Open
Background The metastasis and aggressive nature of prostate cancer (PCa) has become a major malignancy related threat that concerns men’s health. The efficacy of immune monotherapy against PCa is questionable due to its lymphocyte-suppress…
View article: YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6
YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6 Open
Background Tumor-associated macrophages are mainly polarized into the M2 phenotype, remodeling the tumor microenvironment and promoting tumor progression by secreting various cytokines. Methods Tissue microarray consisting of prostate canc…
View article: Current status and perspectives of non-coding RNA and phase separation interactions
Current status and perspectives of non-coding RNA and phase separation interactions Open
Phase separation refers to a phenomenon in which different components of a cell collide and fuse with each other to form droplets such that some components are encapsulated within the droplet and some are blocked outside. It is prevalent i…
View article: Development of genomic instability-associated long non-coding RNA signature: A prognostic risk model of clear cell renal cell carcinoma
Development of genomic instability-associated long non-coding RNA signature: A prognostic risk model of clear cell renal cell carcinoma Open
Purpose Renal clear cell carcinoma (ccRCC) is the most lethal of all pathological subtypes of renal cell carcinoma (RCC). Genomic instability was recently reported to be related to the occurrence and development of kidney cancer. The biolo…
View article: Identification and validation of RB1 as an immune-related prognostic signature based on tumor mutation burdens in bladder cancer
Identification and validation of RB1 as an immune-related prognostic signature based on tumor mutation burdens in bladder cancer Open
Bladder cancer (BCa) is one of the most common malignant tumors in the urinary system. Developing effective prognostic gene and exploring the immune cells that affect the prognosis of tumor are required. Full transcriptome data ( n = 433),…
View article: Curative Effect and Survival Assessment Comparing Gemcitabine and Cisplatin Versus Methotrexate, Vinblastine, Doxorubicin and Cisplatin as Neoadjuvant Therapy for Bladder Cancer: A Systematic Review and Meta-Analysis
Curative Effect and Survival Assessment Comparing Gemcitabine and Cisplatin Versus Methotrexate, Vinblastine, Doxorubicin and Cisplatin as Neoadjuvant Therapy for Bladder Cancer: A Systematic Review and Meta-Analysis Open
Background Neoadjuvant chemotherapy has been accepted as an effective curative treatment for muscle-invasive bladder cancer patients and has resulted in better survival outcomes than radical cystectomy or a cisplatin-based regimen. In the …
View article: High Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio Are Associated With Sarcopenia Risk in Hospitalized Renal Cell Carcinoma Patients
High Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio Are Associated With Sarcopenia Risk in Hospitalized Renal Cell Carcinoma Patients Open
Purpose This study aimed i) to identify the best cutoff points of neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) that predict sarcopenia and ii) to illustrate the association between sarcopenia risk and NLR or PLR in…
View article: Development and Verification of a Prostate Cancer Prognostic Signature Based on an Immunogenomic Landscape Analysis
Development and Verification of a Prostate Cancer Prognostic Signature Based on an Immunogenomic Landscape Analysis Open
Purpose Prostate cancer (PCa) has a high incidence among older men. Until now, there are no immunological markers available to predict PCa patients’ survival. Therefore, it is necessary to explore the immunological characteristics of PCa. …
View article: Relationship Between Pre-operative Blood Glucose Level and Length of Hospital Stay in Patients With Renal Cell Carcinoma Undergoing Laparoscopic Nephrectomy
Relationship Between Pre-operative Blood Glucose Level and Length of Hospital Stay in Patients With Renal Cell Carcinoma Undergoing Laparoscopic Nephrectomy Open
Purpose: The aim of this study was to assess the effect of pre-operative blood glucose (POBG) levels on the length of stay (LOS) in patients with renal cell carcinoma (RCC) undergoing laparoscopic nephrectomy. Methods: We collected clinica…
View article: Clinical patterns and the evolution of relapsing polychondritis based on organ involvement: a Chinese retrospective cohort study
Clinical patterns and the evolution of relapsing polychondritis based on organ involvement: a Chinese retrospective cohort study Open
Background Relapsing polychondritis (RPC) is a rare autoimmune disease and its early diagnosis remains challenging. Defining the clinical patterns and disease course may help early recognition of RPC. Results Sixty-six males and 60 females…
View article: Identification of RB1 Gene as a Immune-Related Prognostic Signature Based on Tumor Mutation Burdens in Bladder Cancer
Identification of RB1 Gene as a Immune-Related Prognostic Signature Based on Tumor Mutation Burdens in Bladder Cancer Open
Background: Bladder cancer (BC) is known as the eleventh most common malignant tumor all over the world, for either males or females. Developing effective regimens targeting more promising biomarkers aiming for better prognosis are require…
View article: Development of a Novel Immune-Related Prognostic Signature for Prostate Cancer
Development of a Novel Immune-Related Prognostic Signature for Prostate Cancer Open
Purpose: Prostate cancer (PCa) has a high incidence in older men. In the field of tumor immunology therapy, there are no strong characteristics to predict the survival of PCa in tumor immunology. Therefore, it is necessary to explore the c…
View article: The Alterations in Methylene Blue/Light-Treated Frozen Plasma Proteins Revealed by Proteomics
The Alterations in Methylene Blue/Light-Treated Frozen Plasma Proteins Revealed by Proteomics Open
Introduction: The aim of this study was to investigate the modified proteins in methylene blue/light-treated frozen plasma (MB-FP) compared with fresh frozen plasma (FFP) in order to gain a better application of MB/light-trea…
View article: Can Mechanical Injury Really Trigger Relapsing Polychondritis? The First Report From A Large Case Series
Can Mechanical Injury Really Trigger Relapsing Polychondritis? The First Report From A Large Case Series Open
Objectives The triggers of relapsing polychondritis (RPC) are not fully characterized. This study was performed to explore the association between mechanical injuries and RPC. Methods The history of mechanical injuries of 127 RPC patients …
View article: Clinical patterns and the evolution of relapsing polychondritis based on organ involvement: a Chinese retrospective cohort study
Clinical patterns and the evolution of relapsing polychondritis based on organ involvement: a Chinese retrospective cohort study Open
Background Relapsing polychondritis(RPC) is a rare autoimmune disease and its early diagnosis pose a challenge to medical committee. Defining the clinical patterns and disease course may help early recognition of RPC. Results Sixty-six mal…
View article: Framework, Procedure, and Tools for Comprehensive Evaluation of Sustainable Stormwater Management: A Review
Framework, Procedure, and Tools for Comprehensive Evaluation of Sustainable Stormwater Management: A Review Open
To better evaluate and enhance the performance and benefit of sustainable stormwater management (SSWM) in developing countries, this study proposes a comprehensive evaluation framework based on thorough literature review. This framework re…
View article: Clinical patterns and the evolution of relapsing polychondritis based on organ involvement: a Chinese retrospective cohort study
Clinical patterns and the evolution of relapsing polychondritis based on organ involvement: a Chinese retrospective cohort study Open
BackgroundRelapsing polychondritis(RPC) is a rare autoimmune disease, of which the diagnosis in early stage is challenging. Defining the clinical patterns and disease evolution may help early recognition of this rare disease.ResultsSixty-s…
View article: Clinical patterns and the evolution of relapsing polychondritis based on organ involvement: analysis of 126 Chinese patients
Clinical patterns and the evolution of relapsing polychondritis based on organ involvement: analysis of 126 Chinese patients Open
Objective To explore the clinical patterns of relapsing polychondritis(RPC) to improve clinicians’ comprehensive understanding of the disease. Methods The electronic records of RPC patients that were hospitalized and followed-up by rheumat…
View article: [Hepatitis B complicated with thrombotic thrombocytopenic purpura after interferon treatment: a case report].
[Hepatitis B complicated with thrombotic thrombocytopenic purpura after interferon treatment: a case report]. Open