Tao Jin
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View article: Serum alpha-1-microglobulin as a predictor of multiple complications in type 2 diabetes mellitus patients
Serum alpha-1-microglobulin as a predictor of multiple complications in type 2 diabetes mellitus patients Open
BACKGROUND Poor glycaemic control in patients with type 2 diabetes mellitus (T2DM) is often accompanied by multiple complications, including diabetic nephropathy (DN), diabetic retinopathy (DR), diabetic peripheral neuropathy (DPN), and ca…
View article: The Stress Hyperglycemia Ratio as a Predictor of Clinical Outcomes in Acute Pancreatitis: A Retrospective Cohort Study
The Stress Hyperglycemia Ratio as a Predictor of Clinical Outcomes in Acute Pancreatitis: A Retrospective Cohort Study Open
Background: The stress hyperglycemia ratio (SHR) has emerged as a promising biomarker for assessing stress-induced hyperglycemia (SH) but has not been evaluated in patients with acute pancreatitis (AP). This study investigates the role of …
View article: Meta-Analysis of the Efficacy and Safety of Umbilical Therapy in Patients with Insomnia
Meta-Analysis of the Efficacy and Safety of Umbilical Therapy in Patients with Insomnia Open
To systematically evaluate the efficacy and safety of umbilical therapy in improving symptoms of insomnia patients. Randomized controlled trials (RCTs) on the application of umbilical therapy in insomnia patients were retrieved from PubMed…
View article: Therapeutic angiogenesis mediated by traditional Chinese Medicine: Advances in cardiovascular disease treatment
Therapeutic angiogenesis mediated by traditional Chinese Medicine: Advances in cardiovascular disease treatment Open
This review highlights angiogenesis as a novel strategy for vascular occlusive diseases and underscores TCM's efficacy through multi-target angiogenic regulation mechanism.However, further research using modern medical technologies is need…
View article: Surgical techniques for modular one-stage emergent pancreaticoduodenectomy for blunt abdominal trauma: experiences from three centres and a review of the literature
Surgical techniques for modular one-stage emergent pancreaticoduodenectomy for blunt abdominal trauma: experiences from three centres and a review of the literature Open
View article: Traditional Chinese medicine Chaiqinchengqi decoction for patients with acute pancreatitis: A randomized clinical trial
Traditional Chinese medicine Chaiqinchengqi decoction for patients with acute pancreatitis: A randomized clinical trial Open
Chaiqinchengqi decoction as an adjunctive therapy significantly reduced the duration of respiratory failure and improved 6-month clinical outcomes of acute pancreatitis in addition to guideline-directed treatments. Further study is needed …
View article: [Clinical Manifestations of Early-Onset Capillary Leak Syndrome in Patients With Multiple Organ Failure Due to Severe Acute Pancreatitis].
[Clinical Manifestations of Early-Onset Capillary Leak Syndrome in Patients With Multiple Organ Failure Due to Severe Acute Pancreatitis]. Open
The CLS model of SAP patients is validated, confirming that CLS is a key factor in the progression from SIRS to MOF. The loss of NAPP is an early and important indicator of CLS persistence and progression to MOF. Additionally, moderate-to-…
View article: The Clinical Characteristics and Outcomes of Acute Pancreatitis Are Different in Elderly Patients: A Single-Center Study over a 6-Year Period
The Clinical Characteristics and Outcomes of Acute Pancreatitis Are Different in Elderly Patients: A Single-Center Study over a 6-Year Period Open
Objectives: This study aims to analyze the clinical characteristics of elderly patients with acute pancreatitis (AP) and investigate the effects of age on the clinical outcomes of AP. Methods: Patients aged ≥ 18 years with AP admitted with…
View article: A comparative study of the application of AJCC 6th and 7th edition gastric cancer staging systems in remnant gastric cancer and the establishment of a prognosis prediction model
A comparative study of the application of AJCC 6th and 7th edition gastric cancer staging systems in remnant gastric cancer and the establishment of a prognosis prediction model Open
Background Remnant gastric cancer (RGC) is a serious complication after gastrectomy that affects the long-term survival rate. At present, there is no international staging system specifically designed for RGC, and clinicians often use the …
View article: Impact of resistance exercise on patients with chronic kidney disease
Impact of resistance exercise on patients with chronic kidney disease Open
Background Chronic kidney disease (CKD) has become an increasingly important public health disease with a high incidence rate and mortality. Although several studies have explored the effectiveness of resistance exercise in improving the p…
View article: Development and validation of a nomogram for Siewert II esophagogastric junction adenocarcinoma: a retrospective analysis
Development and validation of a nomogram for Siewert II esophagogastric junction adenocarcinoma: a retrospective analysis Open
Background: Due to the complex histological type and anatomical structures, there has been considerable debate on the classification of adenocarcinoma of the esophagogastric junction (AEG), especially Siewert II AEG. Furthermore, neither t…
View article: Monocytic HLA-DR Expression in Immune Responses of Acute Pancreatitis and COVID-19
Monocytic HLA-DR Expression in Immune Responses of Acute Pancreatitis and COVID-19 Open
Acute pancreatitis is a common gastrointestinal disease with increasing incidence worldwide. COVID-19 is a potentially life-threatening contagious disease spread throughout the world, caused by severe acute respiratory syndrome coronavirus…
View article: Bacterial lipoproteins shift cellular metabolism to glycolysis in macrophages causing bone erosion
Bacterial lipoproteins shift cellular metabolism to glycolysis in macrophages causing bone erosion Open
Belonging to a group of membrane proteins, bacterial lipoproteins (LPP) are defined by a unique lipid structure at their N-terminus providing the anchor in the bacterial cell membrane. In Gram-positive bacteria, LPP play a key rol…
View article: JMJD3 Is Required for Acute Pancreatitis and Pancreatitis-Associated Lung Injury
JMJD3 Is Required for Acute Pancreatitis and Pancreatitis-Associated Lung Injury Open
Acute pancreatitis (AP) can be complicated by inflammatory disorders of remote organs, such as lung injury, in which Jumonji domain-containing protein 3 (JMJD3) plays a vital role in proinflammatory responses. Currently, we found that JMJD…
View article: Optimising the measurement of intra-bladder pressure in patients with predicted severe acute pancreatitis
Optimising the measurement of intra-bladder pressure in patients with predicted severe acute pancreatitis Open
In predicted SAP patients, measuring IBP at the iliac crest with HoBE15 after instilling 10 mL of NS seems to be appropriate for monitoring IAP.
View article: AGI grade-guided chaiqin chengqi decoction treatment for predicted moderately severe and severe acute pancreatitis (CAP trial): study protocol of a randomised, double-blind, placebo-controlled, parallel-group, pragmatic clinical trial
AGI grade-guided chaiqin chengqi decoction treatment for predicted moderately severe and severe acute pancreatitis (CAP trial): study protocol of a randomised, double-blind, placebo-controlled, parallel-group, pragmatic clinical trial Open
Background Acute pancreatitis (AP) is a common digestive disease with increased incidence globally but without internationally licenced pharmacological therapy. Moderately severe and severe acute pancreatitis (MSAP/SAP) contributes predomi…
View article: Impact of admission and early persistent stress hyperglycaemia on clinical outcomes in acute pancreatitis
Impact of admission and early persistent stress hyperglycaemia on clinical outcomes in acute pancreatitis Open
Background To determine the impact of glucose levels at admission and during first week (early phase) on clinical outcomes in patients with acute pancreatitis (AP) and to investigate the relationship between stress hyperglycaemia (SHG) and…
View article: Safety and efficacy of intravenous hydromorphone patient-controlled analgesia versus intramuscular pethidine in acute pancreatitis: An open-label, randomized controlled trial
Safety and efficacy of intravenous hydromorphone patient-controlled analgesia versus intramuscular pethidine in acute pancreatitis: An open-label, randomized controlled trial Open
Background: Hydromorphone patient-controlled analgesia (PCA) provides satisfactory postoperative pain therapy, but its effect has not been assessed in acute pancreatitis (AP). Aim: To assess the safety and efficacy of intravenous hydromorp…
View article: Optimising fluid requirements after initial resuscitation: A pilot study evaluating mini-fluid challenge and passive leg raising test in patients with predicted severe acute pancreatitis
Optimising fluid requirements after initial resuscitation: A pilot study evaluating mini-fluid challenge and passive leg raising test in patients with predicted severe acute pancreatitis Open
This pilot study found that a protocol for intravenous fluid therapy specifically for the second stage of resuscitation in patients with predicted SAP was safe, feasible, and warrants further investigation.
View article: Transcriptomics and Network Pharmacology Reveal the Protective Effect of Chaiqin Chengqi Decoction on Obesity-Related Alcohol-Induced Acute Pancreatitis via Oxidative Stress and PI3K/Akt Signaling Pathway
Transcriptomics and Network Pharmacology Reveal the Protective Effect of Chaiqin Chengqi Decoction on Obesity-Related Alcohol-Induced Acute Pancreatitis via Oxidative Stress and PI3K/Akt Signaling Pathway Open
Obesity-related acute pancreatitis (AP) is characterized by increasing prevalence worldwide and worse clinical outcomes compared to AP of other etiologies. Chaiqin chengqi decoction (CQCQD), a Chinese herbal formula, has long been used for…
View article: Predicting persistent organ failure on admission in patients with acute pancreatitis: development and validation of a mobile nomogram
Predicting persistent organ failure on admission in patients with acute pancreatitis: development and validation of a mobile nomogram Open
This nomogram can predict POF of AP patients and should be considered for clinical practice and trial allocation.
View article: Extracellular histones cause intestinal epithelium injury and disrupt its barrier function in vitro and in vivo
Extracellular histones cause intestinal epithelium injury and disrupt its barrier function in vitro and in vivo Open
Extracellular histones are cytotoxic to various cells and have been extensively proven a vital mediator of multiple organ injuries. However, the effect of extracellular histones on the intestine remains largely unknown. This study aimed to…
View article: AGI Grade-guided Chaiqin Chengqi Decoction Treatment For Predicted Moderately Severe And Severe Acute Pancreatitis (CAP Trial): Study Protocol of a Randomised, Double-blind, Placebo-controlled, Parallel-group, Pragmatic Clinical Trial
AGI Grade-guided Chaiqin Chengqi Decoction Treatment For Predicted Moderately Severe And Severe Acute Pancreatitis (CAP Trial): Study Protocol of a Randomised, Double-blind, Placebo-controlled, Parallel-group, Pragmatic Clinical Trial Open
Background: Acute pancreatitis (AP) is the common digestive disease with a potentially high risk of mortality. Traditional Chinese medicinal formula chaiqin chengqi decoction (CQCQD) has been used for the management of AP in West China Hos…
View article: Identification of cold tolerance QTLs at the bud burst stage in 211 rice landraces by GWAS
Identification of cold tolerance QTLs at the bud burst stage in 211 rice landraces by GWAS Open
View article: A Mobile Terminal-based Nomogram for Early Predicting Severity of Acute Pancreatitis
A Mobile Terminal-based Nomogram for Early Predicting Severity of Acute Pancreatitis Open
Background: Early prediction of the severity of acute pancreatitis (AP) is important but there is no preferred method in China. We aimed to develop and validate a simple-to-use predictive nomogram for persistent organ failure (POF) on admi…
View article: Stress Hyperglycemia Is Independently Associated with Persistent Organ Failure in Acute Pancreatitis
Stress Hyperglycemia Is Independently Associated with Persistent Organ Failure in Acute Pancreatitis Open
BACKGROUND/AIMS: Stress hyperglycemia is common in critical illness but it has not been clearly studied in patients with acute pancreatitis (AP). This study aimed to investigate the specific blood glucose (BG) level that defines stress hyp…
View article: Depressive males have higher odds of lower urinary tract symptoms suggestive of benign prostatic hyperplasia
Depressive males have higher odds of lower urinary tract symptoms suggestive of benign prostatic hyperplasia Open
Lower urinary tract symptoms suggestive of benign prostate hyperplasia (LUTS/BPH) and depression are both increasing in Chinese aging males. However, the relationship still remains unknown. To explore their relationship, a retrospective co…
View article: Chaiqin chengqi decoction ameliorates acute pancreatitis in mice via inhibition of neuron activation-mediated acinar cell SP/NK1R signaling pathways
Chaiqin chengqi decoction ameliorates acute pancreatitis in mice via inhibition of neuron activation-mediated acinar cell SP/NK1R signaling pathways Open
CQCQD ameliorated cerulein-induced AP and its associated pain via inhibiting neuron activation-mediated pancreatic acinar cell SP-NK1R signaling pathways and its active compounds baicalin, emodin, and magnolol contributed to this effect.
View article: Additional file 2 of Identification of cold tolerance QTLs at the bud burst stage in 211 rice landraces by GWAS
Additional file 2 of Identification of cold tolerance QTLs at the bud burst stage in 211 rice landraces by GWAS Open
Additional file 2: Table S2. SR of the 211 rice varieties
View article: Additional file 1 of Identification of cold tolerance QTLs at the bud burst stage in 211 rice landraces by GWAS
Additional file 1 of Identification of cold tolerance QTLs at the bud burst stage in 211 rice landraces by GWAS Open
Additional file 1: Table S1. Geographical distribution and indica or japonica type of 211 rice varieties