Tianyi Xia
YOU?
Author Swipe
View article: Predicting tumor micronecrosis in hepatocellular carcinoma using pretreatment contrast-enhanced CT radiomics model: a multi-center study
Predicting tumor micronecrosis in hepatocellular carcinoma using pretreatment contrast-enhanced CT radiomics model: a multi-center study Open
Tumor micronecrosis is a validated malignancy biomarker with poor prognosis in hepatocellular carcinoma (HCC), but currently lacks reliable preoperative detection methods. We developed a radiomics model for predicting tumor micronecrosis u…
View article: DynPerturb:Dynamic Perturbation Modeling for Spatiotemporal Single-Cell Systems
DynPerturb:Dynamic Perturbation Modeling for Spatiotemporal Single-Cell Systems Open
Perturbation responses in multicellular systems are inherently spatiotemporal, governed by temporal dynamics, perturbation intensity, and tissue context. However, existing approaches rarely capture explicit spatiotemporal perturbation dyna…
View article: Anatomical resection is associated with reduced early recurrences in HCC: A machine learning analysis
Anatomical resection is associated with reduced early recurrences in HCC: A machine learning analysis Open
Causal forest modeling enables the detection of HTEs of AR in patients with HCC based on multiple clinical-radiological characteristics. Radiological tumor size ≤5 cm and non-smooth tumor margins were identified as significant modifiers an…
View article: BioLLM: A standardized framework for integrating and benchmarking single-cell foundation models
BioLLM: A standardized framework for integrating and benchmarking single-cell foundation models Open
View article: A radiomics-based model for predicting lymph nodes metastasis of pancreatic ductal adenocarcinoma: a multicenter study
A radiomics-based model for predicting lymph nodes metastasis of pancreatic ductal adenocarcinoma: a multicenter study Open
View article: Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges
Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges Open
Intervertebral disc degeneration (IVDD), a major cause of low back pain, poses significant global health and socioeconomic challenges. Current therapies have limited effectiveness in reversing degeneration, which underscores the need for a…
View article: Causal Relationship Between Cerebrospinal Fluid Metabolites and Intervertebral Disc Disease: A Bidirectional Mendelian Randomization Study
Causal Relationship Between Cerebrospinal Fluid Metabolites and Intervertebral Disc Disease: A Bidirectional Mendelian Randomization Study Open
Background: Intervertebral disc degeneration (IVDD) is caused by an imbalance between the catabolic and anabolic processes within intervertebral disc tissue. Several studies have suggested a potential association between cerebrospinal flui…
View article: UniCell: Towards a Unified Solution for Cell Annotation, Nomenclature Harmonization, Atlas Construction in Single-Cell Transcriptomics
UniCell: Towards a Unified Solution for Cell Annotation, Nomenclature Harmonization, Atlas Construction in Single-Cell Transcriptomics Open
Standardizing cell type annotations across single-cell RNA-seq datasets remains a major challenge due to inconsistencies in nomenclature, variation in annotation granularity, and the presence of rare or previously unseen populations. We pr…
View article: Supplementary figure1 from Predicting c-KIT Inhibitor Efficacy in Patient-Derived Models of Sinonasal Mucosal Melanomas through Integrated Histogram Analysis of Whole-Tumor DKI, IVIM, and DCE-MRI
Supplementary figure1 from Predicting c-KIT Inhibitor Efficacy in Patient-Derived Models of Sinonasal Mucosal Melanomas through Integrated Histogram Analysis of Whole-Tumor DKI, IVIM, and DCE-MRI Open
Supplementary figure
View article: Data from Predicting c-KIT Inhibitor Efficacy in Patient-Derived Models of Sinonasal Mucosal Melanomas through Integrated Histogram Analysis of Whole-Tumor DKI, IVIM, and DCE-MRI
Data from Predicting c-KIT Inhibitor Efficacy in Patient-Derived Models of Sinonasal Mucosal Melanomas through Integrated Histogram Analysis of Whole-Tumor DKI, IVIM, and DCE-MRI Open
Purpose:To evaluate whole-tumor histogram analysis of diffusion kurtosis imaging (DKI), intravoxel incoherent motion (IVIM), and dynamic contrast-enhanced MRI (DCE-MRI) in predicting the efficacy of imatinib, a c-KIT inhibitor, for treatin…
View article: Supplementary Table1 from Predicting c-KIT Inhibitor Efficacy in Patient-Derived Models of Sinonasal Mucosal Melanomas through Integrated Histogram Analysis of Whole-Tumor DKI, IVIM, and DCE-MRI
Supplementary Table1 from Predicting c-KIT Inhibitor Efficacy in Patient-Derived Models of Sinonasal Mucosal Melanomas through Integrated Histogram Analysis of Whole-Tumor DKI, IVIM, and DCE-MRI Open
Supplementary Tables
View article: Exploring the role of gut microbiota in intervertebral disc degeneration: insights from bidirectional Mendelian randomization analysis
Exploring the role of gut microbiota in intervertebral disc degeneration: insights from bidirectional Mendelian randomization analysis Open
We used a bidirectional Mendelian randomization approach to identify various gut microbiota associated with IVDD. Our findings lay the foundation for further exploration of the pathogenesis and treatment strategies of gut microbiota and IV…
View article: Stereopy: modeling comparative and spatiotemporal cellular heterogeneity via multi-sample spatial transcriptomics
Stereopy: modeling comparative and spatiotemporal cellular heterogeneity via multi-sample spatial transcriptomics Open
Understanding complex biological systems requires tracing cellular dynamic changes across conditions, time, and space. However, integrating multi-sample data in a unified way to explore cellular heterogeneity remains challenging. Here, we …
View article: Proinflammatory macrophages release CXCL5 to regulate T cell function and limit effects of αPD-1 in steatosis-driven liver cancer
Proinflammatory macrophages release CXCL5 to regulate T cell function and limit effects of αPD-1 in steatosis-driven liver cancer Open
In this study, we investigated the role of CXCL5 in the progression from steatosis to liver cancer. We uncovered a novel inhibitory role of CXCL5 in T cell recruitment, with implications for NAC-targeted therapy and immune checkpoint syner…
View article: Attitudes of radiologists and interns toward the adoption of GPT-like technologies: a National Survey Study in China
Attitudes of radiologists and interns toward the adoption of GPT-like technologies: a National Survey Study in China Open
Objectives To investigate the attitudes of Chinese radiologists or interns towards generative pre-trained (GPT)-like technologies. Methods A prospective survey was distributed to 1339 Chinese radiologists or interns via an online platform …
View article: Identification of PANoptosis associated lncRNAs associated with clinical prognosis and immune infiltration microenvironment in colon adenocarcinoma
Identification of PANoptosis associated lncRNAs associated with clinical prognosis and immune infiltration microenvironment in colon adenocarcinoma Open
View article: TRACE Model: Predicting Treatment Response to Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma
TRACE Model: Predicting Treatment Response to Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma Open
The TRACE model exhibited favorable predictive capability for six-month TACE response, and holds potential as a marker for long-term survival outcomes.
View article: PCLCD: Patch-Based Contrastive Learning for Remote Sensing Image Change Detection
PCLCD: Patch-Based Contrastive Learning for Remote Sensing Image Change Detection Open
Current remote sensing change detection (CD) remains a challenging task due to severe pseudo-change interference and insufficient local feature modeling in complex scenarios. To address these issues, we propose a novel patch-based contrast…
View article: A study on site selection of coal mine emergency material reserve based on genetic algorithm
A study on site selection of coal mine emergency material reserve based on genetic algorithm Open
Coal mine accidents often lead to economic losses and casualties. Establishing a coal mine emergency reserve can help rescue materials reach the accidental coal mine site more quickly, so the site selection of the emergency reserve is cruc…
View article: Genetic Insights into the Causal Role of Plasma Proteins and Blood Pressure in White Matter Hyperintensities and Therapeutic Target Discovery
Genetic Insights into the Causal Role of Plasma Proteins and Blood Pressure in White Matter Hyperintensities and Therapeutic Target Discovery Open
View article: Causal impacts of 731 immunocyte phenotypes on colorectal cancer-evidence from a bidirectional two-sample Mendelian randomization
Causal impacts of 731 immunocyte phenotypes on colorectal cancer-evidence from a bidirectional two-sample Mendelian randomization Open
Colorectal cancer is one of the most common and lethal malignancies, and various factors have been confirmed to contribute to its occurrence. However, the causal role of immune cell-specific changes in the development of colorectal cancer …
View article: BioLLM: A Standardized Framework for Integrating and Benchmarking Single-Cell Foundation Models
BioLLM: A Standardized Framework for Integrating and Benchmarking Single-Cell Foundation Models Open
The application and evaluation of single cell foundational models (scFMs) present significant challenges stemming from the heterogeneity of architectural frameworks and coding standards. To address these issues, we introduce BioLLM, a fram…
View article: Safety Management of Ultra-high Voltage Substation Equipment Operation
Safety Management of Ultra-high Voltage Substation Equipment Operation Open
Ultra-high voltage substation plays an important role in the modern power system. It is the transmission hub of power, connecting large power plants and end users. With the continuous expansion of power grid scale and the improvement of vo…
View article: A novel risk stratification approach and molecular subgroup characterization based on coagulation related genes in colon adenocarcinoma
A novel risk stratification approach and molecular subgroup characterization based on coagulation related genes in colon adenocarcinoma Open
Colon adenocarcinoma (COAD) represents a significant health concern within the population. Advancing our understanding of COAD is imperative for early detection, enabling personalized treatment interventions, and facilitating the developme…
View article: ST-GEARS: Advancing 3D downstream research through accurate spatial information recovery
ST-GEARS: Advancing 3D downstream research through accurate spatial information recovery Open
Three-dimensional Spatial Transcriptomics has revolutionized our understanding of tissue regionalization, organogenesis, and development. However, existing approaches overlook either spatial information or experiment-induced distortions, l…
View article: Three-dimension transcriptomics maps of whole mouse embryo during organogenesis
Three-dimension transcriptomics maps of whole mouse embryo during organogenesis Open
Understanding mammalian development heavily relies on classical animal models like the house mouse (Mus musculus). Advanced spatial transcriptomics has enabled biologists to break new ground in studies of molecular dynamics and cellular pa…
View article: Signal enhancement ratio of multi-phase contrast-enhanced MRI: an imaging biomarker for survival in pancreatic adenocarcinoma
Signal enhancement ratio of multi-phase contrast-enhanced MRI: an imaging biomarker for survival in pancreatic adenocarcinoma Open
Objectives To evaluate signal enhancement ratio (SER) for tissue characterization and prognosis stratification in pancreatic adenocarcinoma (PDAC), with quantitative histopathological analysis (QHA) as the reference standard. Methods This …
View article: Four-dimensional flow magnetic resonance imaging for noninvasive diagnosis of clinically significant portal hypertension and high-risk gastroesophageal varices in patients with cirrhosis
Four-dimensional flow magnetic resonance imaging for noninvasive diagnosis of clinically significant portal hypertension and high-risk gastroesophageal varices in patients with cirrhosis Open
Introduction: Noninvasive diagnoses of clinically significant portal hypertension (CSPH) and high-risk gastroesophageal varices are clinically relevant but challenging. Four-dimensional (4D) flow magnetic resonance imaging (MRI) provides c…
View article: Corrigendum to ‘Predicting post-resection recurrence by integrating imaging-based surrogates of distinct vascular patterns of hepatocellular carcinoma’ (JHEP Reports 5 [2023] 100806)
Corrigendum to ‘Predicting post-resection recurrence by integrating imaging-based surrogates of distinct vascular patterns of hepatocellular carcinoma’ (JHEP Reports 5 [2023] 100806) Open
View article: Estimating Heterogeneous Treatment Effects of Anatomical Resection in Hepatocellular Carcinoma: A Causal Machine Learning Analysis
Estimating Heterogeneous Treatment Effects of Anatomical Resection in Hepatocellular Carcinoma: A Causal Machine Learning Analysis Open