Tianzheng Yu
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View article: Mitochondrial Dysfunction in Sickle Cell Trait Carriers With Exertional Collapse
Mitochondrial Dysfunction in Sickle Cell Trait Carriers With Exertional Collapse Open
Sickle cell trait (SCT) increases the risk of sudden death and exertional rhabdomyolysis (ER) in athletes and Service Members (SMs) during intense exercise. Exertional injuries in SCT carriers can result in exercise collapse associated wit…
View article: Collaborative Impact of Curcumin, Astaxanthin, and Nicotinamide Riboside on Sustaining Mitochondrial Integrity and Alleviating Heat-Induced Oxidative Stress
Collaborative Impact of Curcumin, Astaxanthin, and Nicotinamide Riboside on Sustaining Mitochondrial Integrity and Alleviating Heat-Induced Oxidative Stress Open
View article: Dose-Dependent Effects of Radiation on Mitochondrial Morphology and Clonogenic Cell Survival in Human Microvascular Endothelial Cells
Dose-Dependent Effects of Radiation on Mitochondrial Morphology and Clonogenic Cell Survival in Human Microvascular Endothelial Cells Open
To better understand radiation-induced organ dysfunction at both high and low doses, it is critical to understand how endothelial cells (ECs) respond to radiation. The impact of irradiation (IR) on ECs varies depending on the dose administ…
View article: <scp>5‐Hydroxymethylfurfural</scp> reduces skeletal muscle superoxide production and modifies force production in rats exposed to hypobaric hypoxia
<span>5‐Hydroxymethylfurfural</span> reduces skeletal muscle superoxide production and modifies force production in rats exposed to hypobaric hypoxia Open
Decreased blood‐tissue oxygenation at high altitude (HA) increases mitochondrial oxidant production and reduces exercise capacity. 5‐Hydroxymethylfurfural (5‐HMF) is an antioxidant that increases hemoglobin's binding affinity for oxygen. F…
View article: Mitochondrial Fission as a Therapeutic Target for Metabolic Diseases: Insights into Antioxidant Strategies
Mitochondrial Fission as a Therapeutic Target for Metabolic Diseases: Insights into Antioxidant Strategies Open
Mitochondrial fission is a crucial process in maintaining metabolic homeostasis in normal physiology and under conditions of stress. Its dysregulation has been associated with several metabolic diseases, including, but not limited to, obes…
View article: BJN volume 129 issue 6 Cover and Back matter
BJN volume 129 issue 6 Cover and Back matter Open
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View article: Acute heat stress-indued apoptosis in mouse skeletal muscle is not associated with alteration of glutamine homeostasis
Acute heat stress-indued apoptosis in mouse skeletal muscle is not associated with alteration of glutamine homeostasis Open
We previously demonstrated that exposing mice to heat causes functional and ultrastructural mitochondrial alterations and apoptosis in skeletal muscle. Emerging evidence indicates that glutamine (Gln) deprivation may increase cell suscepti…
View article: IL-18 binding protein (IL-18BP) as a novel radiation countermeasure after radiation exposure in mice
IL-18 binding protein (IL-18BP) as a novel radiation countermeasure after radiation exposure in mice Open
View article: Glutamine depletion disrupts mitochondrial integrity and impairs C2C12 myoblast proliferation, differentiation, and the heat-shock response
Glutamine depletion disrupts mitochondrial integrity and impairs C2C12 myoblast proliferation, differentiation, and the heat-shock response Open
View article: Mouse liver is more resistant than skeletal muscle to heat-induced apoptosis
Mouse liver is more resistant than skeletal muscle to heat-induced apoptosis Open
View article: Curcumin Ameliorates Heat-Induced Injury through NADPH Oxidase–Dependent Redox Signaling and Mitochondrial Preservation in C2C12 Myoblasts and Mouse Skeletal Muscle
Curcumin Ameliorates Heat-Induced Injury through NADPH Oxidase–Dependent Redox Signaling and Mitochondrial Preservation in C2C12 Myoblasts and Mouse Skeletal Muscle Open
View article: Association of Telomere Length, a Cellular Aging Marker, with Depression, PTSD and Hostility
Association of Telomere Length, a Cellular Aging Marker, with Depression, PTSD and Hostility Open
Depression, PTSD, and hostility are common mental conditions that are associated with aging. A growing body of research has highlighted the possible effects of depression, PTSD, and hostility on aging and telomere length (TL), a cellular a…
View article: Role of dynamin‐related protein 1‐mediated mitochondrial fission in resistance of mouse C2C12 myoblasts to heat injury
Role of dynamin‐related protein 1‐mediated mitochondrial fission in resistance of mouse C2C12 myoblasts to heat injury Open
Key points Understanding how skeletal muscles respond to high temperatures may help develop strategies for improving exercise tolerance and preventing heat injury. Mitochondria regulate cell survival by constantly changing their morphology…
View article: Decreasing mitochondrial fission diminishes vascular smooth muscle cell migration and ameliorates intimal hyperplasia
Decreasing mitochondrial fission diminishes vascular smooth muscle cell migration and ameliorates intimal hyperplasia Open
Mitochondrial fission is an integral process in cell migration, and controlling mitochondrial fission can limit VSMC migration and the pathological intimal hyperplasia by altering mitochondrial energetics and ROS levels.
View article: Morphological control of mitochondrial bioenergetics
Morphological control of mitochondrial bioenergetics Open
The major function of mitochondria is production and supply of cellular energy. Mitochondria are highly dynamic organelles undergoing frequent shape changes via fission and fusion. Many studies have elucidated the molecular components medi…