Tianzhi Zhang
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View article: Pathological complete response in advanced intrahepatic cholangiocarcinoma was achieved through tri-modal therapy: A case report and review of literature
Pathological complete response in advanced intrahepatic cholangiocarcinoma was achieved through tri-modal therapy: A case report and review of literature Open
BACKGROUND Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with limited treatment options and a poor prognosis, particularly in unresectable or metastatic cases. Tri-modal strategies combining systemic chemotherapy, targe…
View article: Text-Image Feature Fine-Grained Learning for Joint Multimodal Aspect-Based Sentiment Analysis
Text-Image Feature Fine-Grained Learning for Joint Multimodal Aspect-Based Sentiment Analysis Open
View article: Reconceptualizing the Teaching of the Five-Paragraph Essay Through Concept-Based Language Instruction to English as a Second Language Writers
Reconceptualizing the Teaching of the Five-Paragraph Essay Through Concept-Based Language Instruction to English as a Second Language Writers Open
This case study reports a pedagogical approach informed by Concept-Based Language Instruction, which aimed to orient English as a second language learners to a systematic conceptual understanding of rhetorical skills in five-paragraph essa…
View article: HnRNPR-mediated UPF3B mRNA splicing drives hepatocellular carcinoma metastasis
HnRNPR-mediated UPF3B mRNA splicing drives hepatocellular carcinoma metastasis Open
View article: Overexpression of KLHL22 correlates with poor prognosis in patients with triple-negative breast cancer
Overexpression of KLHL22 correlates with poor prognosis in patients with triple-negative breast cancer Open
The present study concludes that KLHL22 may serve as a biomarker for poor prognosis in patients with TNBC.
View article: Comparative Response of Arbuscular Mycorrhizal Fungi versus Endophytic Fungi in Tangor Citrus: Photosynthetic Efficiency and P-Acquisition Traits
Comparative Response of Arbuscular Mycorrhizal Fungi versus Endophytic Fungi in Tangor Citrus: Photosynthetic Efficiency and P-Acquisition Traits Open
Citrus plants are prone to phosphorus (P) deficiency, especially in acidic soil, making them more dependent on root-associated endophytic fungi for growth and development. Beni-Madonna, a hybrid of Citrus nanko × C. amakusa, is a citrus kn…
View article: Comprehensive analysis of 33 human cancers reveals clinical implications and immunotherapeutic value of the solute carrier family 35 member A2
Comprehensive analysis of 33 human cancers reveals clinical implications and immunotherapeutic value of the solute carrier family 35 member A2 Open
Background Solute carrier family 35 member A2 (SLC35A2), which belongs to the SLC35 solute carrier family of human nucleoside sugar transporters, has shown regulatory roles in various tumors and neoplasms. However, the function of SLC35A2 …
View article: Ectopic esophageal sebaceous glands: a case report
Ectopic esophageal sebaceous glands: a case report Open
View article: Clinicopathologic Characteristics of Differentiated Thyroid Carcinoma in Children and Adolescents
Clinicopathologic Characteristics of Differentiated Thyroid Carcinoma in Children and Adolescents Open
Objective: To investigate the clinicopathologic features of differentiated thyroid carcinoma in children and adolescents. Methods: The clinical data of 7 children and adolescents with differentiated thyroid carcinoma were retrospectively a…
View article: Histopathologic and Immunohistochemical Analysis of 66 Cases of Gastrointestinal Stromal Tumor
Histopathologic and Immunohistochemical Analysis of 66 Cases of Gastrointestinal Stromal Tumor Open
Background and Objective: To investigate the histopathological characteristics and immunohistochemistry of gastrointestinal stromal tumors (GIST). Immunohistochemistry (IHC) refers to the expression and meaning of CD117, DOG-1, CD34. Metho…
View article: The UPF3B Splice Variant Modulated by HnRNPR Promotes Invasion and Metastasis of Hepatocellular Carcinoma via Inhibiting the CDH1/Hippo Pathway
The UPF3B Splice Variant Modulated by HnRNPR Promotes Invasion and Metastasis of Hepatocellular Carcinoma via Inhibiting the CDH1/Hippo Pathway Open
View article: Geochronology, geochemistry, and Sr–Nd–Hf isotopes of the Cretaceous igneous rocks in the Zhilingtou area, SE China, and their geological significance
Geochronology, geochemistry, and Sr–Nd–Hf isotopes of the Cretaceous igneous rocks in the Zhilingtou area, SE China, and their geological significance Open
The Zhilingtou deposit is one of the typical porphyry Mo deposits in South China. Disseminated and veinlet Mo ores occur in the roof pendant of the granite porphyry or the contact between the granite porphyry and the Badu Group gneisses, a…
View article: Carrier-free multifunctional nanomedicine for intraperitoneal disseminated ovarian cancer therapy
Carrier-free multifunctional nanomedicine for intraperitoneal disseminated ovarian cancer therapy Open
View article: Carrier-Free Multifunctional Nanomedicine For Intraperitoneal Disseminated Ovarian Cancer Therapy
Carrier-Free Multifunctional Nanomedicine For Intraperitoneal Disseminated Ovarian Cancer Therapy Open
Background: Ovarian cancer is the most lethal gynecological cancer which is characterized by extensive peritoneal implantation metastasis and malignant ascites. Despite advances in diagnosis and treatment in recent years, the five-year sur…
View article: Effect Evaluation of “Organ System-Centered” Course in Clinical Teaching
Effect Evaluation of “Organ System-Centered” Course in Clinical Teaching Open
Objective: To evaluate the effect of applying the integrated teaching method of clinical medical courses centered on organ system in clinical teaching. Methods: 120 clinical medical students of grade 2019 in our school were selected as the…
View article: Tubular Carcinoma of the Breast: A Clinicopathological Analysis of Two Cases
Tubular Carcinoma of the Breast: A Clinicopathological Analysis of Two Cases Open
Tubular Carcinoma (TC) of the breast, also known as tubular carcinoma or well-differentiated adenocarcinoma, is defined as a special type of breast cancer consisting of well-differentiated tubular structures with excellent prognosis by WHO…
View article: METTL16 promotes cell proliferation by up‐regulating cyclin D1 expression in gastric cancer
METTL16 promotes cell proliferation by up‐regulating cyclin D1 expression in gastric cancer Open
N6‐methyladenosine (m6A) is a well‐known modification of RNA. However, as a key m6A methyltransferase, METTL16 has not been thoroughly studied in gastric cancer (GC). Here, the biological role of METTL16 in GC and its underlying mechanism …
View article: Which Way to Choose for the Treatment of Metastatic Prostate Cancer: A Case Report and Literature Review
Which Way to Choose for the Treatment of Metastatic Prostate Cancer: A Case Report and Literature Review Open
Background Prostate cancer (PCa) is the second most common cancer among males in the world and the majority of patients will eventually progress to the metastatic phase. How to choose an effective way for the treatment of metastatic PCa, e…
View article: LGALS3 Is a Poor Prognostic Factor in Diffusely Infiltrating Gliomas and Is Closely Correlated With CD163+ Tumor-Associated Macrophages
LGALS3 Is a Poor Prognostic Factor in Diffusely Infiltrating Gliomas and Is Closely Correlated With CD163+ Tumor-Associated Macrophages Open
Background: Glioma, the most common brain tumor, is a heterogeneous group of glia-derived tumors, the majority of which have characteristics of diffuse infiltration and immunosuppression. The LGALS protein family is a large class of…