Yuying Li
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View article: Large Strain Extrusion Machining of 7075 Aluminum Alloy with Micro-Textured Tools and Analysis of Chip Morphology and Microstructure
Large Strain Extrusion Machining of 7075 Aluminum Alloy with Micro-Textured Tools and Analysis of Chip Morphology and Microstructure Open
Large Strain Extrusion Machining (LSEM) is an intensive plastic deformation process evolved from conventional machining, enabling effective control over chip morphology and grain refinement. This process often generates high cutting temper…
View article: Verbenalin attenuates renal tubular epithelial ferroptosis in ischemia–reperfusion injury induced AKI by regulating the HIF-1α/HO-1 signaling pathway
Verbenalin attenuates renal tubular epithelial ferroptosis in ischemia–reperfusion injury induced AKI by regulating the HIF-1α/HO-1 signaling pathway Open
View article: Micro-Textured Tool Extrusion Cutting of 7075 Aluminum Alloy and Analysis of Chip Morphology and Microstructure
Micro-Textured Tool Extrusion Cutting of 7075 Aluminum Alloy and Analysis of Chip Morphology and Microstructure Open
Extrusion cutting is an intensive plastic deformation process developed from conventional cutting. To address issues such as high cutting temperatures and friction instability during machining, this study proposes integrating microtextured…
View article: Joint Transcriptomic Analysis of the Effect of Iron Concentration on Piglet Liver and Functional Validation of Iron Regulatory Genes
Joint Transcriptomic Analysis of the Effect of Iron Concentration on Piglet Liver and Functional Validation of Iron Regulatory Genes Open
Iron plays a key role in oxygen transport, hematopoiesis, and hypoxia adaptation. This study aimed to explore the dynamic response mechanism of the iron regulatory network and key genes in Duroc piglets. Eighteen weaned piglets were random…
View article: Parallel Time-Frequency Multi-Scale Attention with Dynamic Convolution for Environmental Sound Classification
Parallel Time-Frequency Multi-Scale Attention with Dynamic Convolution for Environmental Sound Classification Open
Convolutional neural network (CNN) models are widely used for environmental sound classification (ESC). However, 2-D convolutions assume translation invariance along both time and frequency axes, while in practice the frequency dimension i…
View article: Cryo-EM structure of the full-length LGR4-RSPOs complex and a targeting nanobody for anti-obesity therapy
Cryo-EM structure of the full-length LGR4-RSPOs complex and a targeting nanobody for anti-obesity therapy Open
View article: Mechanism of <i>Lysobacter enzymogenes</i> resistance toward fungi induced by fungal-derived signal α-terpinene
Mechanism of <i>Lysobacter enzymogenes</i> resistance toward fungi induced by fungal-derived signal α-terpinene Open
Bacterial-fungal interactions (BFI) are critical drivers of ecosystem functions, and their molecular mechanisms remain incompletely understood. Chemical signals are crucial mediators of microbial communication, but the signaling mechanisms…
View article: Metal-organic framework-mediated antioxidant enzyme delivery in disease treatment
Metal-organic framework-mediated antioxidant enzyme delivery in disease treatment Open
View article: The systemic inflammatory response index as a risk factor for all-cause and cardiovascular mortality among individuals with coronary artery disease: evidence from the cohort study of NHANES 1999–2018
The systemic inflammatory response index as a risk factor for all-cause and cardiovascular mortality among individuals with coronary artery disease: evidence from the cohort study of NHANES 1999–2018 Open
SIRI was independently associated with all-cause and CVD mortality, and the dose-response relationship was J-shaped. SIRI might serve as a valid predictor for all-cause and CVD mortality both in the short and long terms.
View article: Efficacy and safety of shensong yangxin capsules for persistent atrial fibrillation: a Systematic Review and meta-analysis of randomized controlled trials
Efficacy and safety of shensong yangxin capsules for persistent atrial fibrillation: a Systematic Review and meta-analysis of randomized controlled trials Open
Background Shensong Yangxin (SSYX), a standardized Chinese preparation, is widely utilized in arrhythmia treatment. This research sought to assess the clinical advantages of SSYX for persistent atrial fibrillation (PsAF). Methods We search…
View article: Feeding Behavior and Ecological Significance of Craspedacusta sowerbii in a Freshwater Reservoir: Insights from Prey Composition and Trophic Interactions
Feeding Behavior and Ecological Significance of Craspedacusta sowerbii in a Freshwater Reservoir: Insights from Prey Composition and Trophic Interactions Open
This study investigates the feeding behavior and ecological role of Craspedacusta sowerbii in the Danjiangkou Reservoir, a crucial freshwater source in central China. Through in situ cultivation, microscopic examination, and amplicon seque…
View article: Species and functional composition of cecal microbiota and resistance gene diversity in different Yunnan native chicken breeds: A metagenomic analysis
Species and functional composition of cecal microbiota and resistance gene diversity in different Yunnan native chicken breeds: A metagenomic analysis Open
View article: PABPC4 Inhibits SADS-CoV Replication by Degrading the Nucleocapsid Protein Through Selective Autophagy
PABPC4 Inhibits SADS-CoV Replication by Degrading the Nucleocapsid Protein Through Selective Autophagy Open
Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a novel enteric coronavirus that causes severe clinical diarrhea and intestinal pathological injury in pigs. Selective autophagy is an important mechanism of host defense against viru…
View article: <i>Faecalibacterium prausnitzii</i> Suppresses Mitophagy to Alleviate Muscle Atrophy in Chronic Renal Failure With Protein‐Energy Wasting
<i>Faecalibacterium prausnitzii</i> Suppresses Mitophagy to Alleviate Muscle Atrophy in Chronic Renal Failure With Protein‐Energy Wasting Open
Protein‐energy wasting (PEW) facilitates major adverse clinical outcomes in chronic renal failure (CRF), with current therapies not suitable for all patients. Faecalibacterium prausnitzii ( F. prausnitzii ) can alleviate chronic kidney dis…
View article: Erratum to the ‘Long non-coding RNAs-sphingolipid metabolism nexus: Potential targets for cancer treatment’ Pharmacol. Res. 210 (December) (2024) 107539
Erratum to the ‘Long non-coding RNAs-sphingolipid metabolism nexus: Potential targets for cancer treatment’ Pharmacol. Res. 210 (December) (2024) 107539 Open
View article: Aspartate Metabolism‐Driven Gut Microbiota Dynamics and RIP‐Dependent Mitochondrial Function Counteract Oxidative Stress
Aspartate Metabolism‐Driven Gut Microbiota Dynamics and RIP‐Dependent Mitochondrial Function Counteract Oxidative Stress Open
Aspartate (Asp) metabolism‐mediated antioxidant functions have important implications for neonatal growth and intestinal health; however, the antioxidant mechanisms through which Asp regulates the gut microbiota and influences RIP activati…
View article: Structural insights into the LGR4-RSPO2-ZNRF3 complexes regulating WNT/β-catenin signaling
Structural insights into the LGR4-RSPO2-ZNRF3 complexes regulating WNT/β-catenin signaling Open
View article: Amino acid metabolism-mediated immune cell fate and function in pigs
Amino acid metabolism-mediated immune cell fate and function in pigs Open
Amino acids are fundamental to sustaining life. They are crucial for intracellular processes, such as energy metabolism, biosynthesis of nucleotides, and maintenance of oxidative homeostasis. These processes ensure the proper functioning o…
View article: Electrocatalytic Conversion of Co2 to Methane: A First-Principles Study of Transition Metal-Embedded C5n2 Monolayers
Electrocatalytic Conversion of Co2 to Methane: A First-Principles Study of Transition Metal-Embedded C5n2 Monolayers Open
View article: Association of remnant cholesterol with insulin resistance and type 2 diabetes: mediation analyses from NHANES 1999–2020
Association of remnant cholesterol with insulin resistance and type 2 diabetes: mediation analyses from NHANES 1999–2020 Open
View article: Long non-coding RNAs-sphingolipid metabolism nexus: Potential targets for cancer treatment
Long non-coding RNAs-sphingolipid metabolism nexus: Potential targets for cancer treatment Open
Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators of cancer pathogenesis, influencing various cellular processes and contributing to tumorigenesis. Sphingolipid metabolism has garnered interest as a potential target for can…
View article: Tertiary Lymphoid Structure in Dental Pulp: The Role in Combating Bacterial Infections
Tertiary Lymphoid Structure in Dental Pulp: The Role in Combating Bacterial Infections Open
Tertiary lymphoid structure (TLS) is associated with various pathologies, including those of cancers and chronic infections. Depending on the organ, multiple factors regulate the formation of TLS. However, the role of TLS in immune respons…
View article: Effect of neurointerventional therapy combined with tirofiban on neurological function and electroencephalographic indices in patients with cerebral infarction
Effect of neurointerventional therapy combined with tirofiban on neurological function and electroencephalographic indices in patients with cerebral infarction Open
View article: Deer antler stem cells immortalization by modulation of hTERT and the small extracellular vesicles characters
Deer antler stem cells immortalization by modulation of hTERT and the small extracellular vesicles characters Open
Background Deer antler stem cells (AnSCs) exhibit properties of both embryonic and mesenchymal stem cells, with superior self-renewal and proliferation, which drive rapid antler growth and regeneration. AnSCs and their derived small extrac…
View article: Efficacy of short-term Peg-IFN α-2b treatment in chronic hepatitis B patients with ultra-low HBsAg levels: a retrospective cohort study
Efficacy of short-term Peg-IFN α-2b treatment in chronic hepatitis B patients with ultra-low HBsAg levels: a retrospective cohort study Open
Our findings confirm that a 24-week course of Peg-IFN α-2b yields robust efficacy in CHB patients with ultra-low HBsAg levels. Prolonging treatment beyond the 24-week threshold is deemed unnecessary. Both baseline HBsAg level and the prese…
View article: A comprehensive survey of the application of swarm intelligent optimization algorithm in photovoltaic energy storage systems
A comprehensive survey of the application of swarm intelligent optimization algorithm in photovoltaic energy storage systems Open
With the rapid development of renewable energy, photovoltaic energy storage systems (PV-ESS) play an important role in improving energy efficiency, ensuring grid stability and promoting energy transition. As an important part of the micro-…
View article: Epidemiological and evolutionary analysis of canine circovirus from 1996 to 2023
Epidemiological and evolutionary analysis of canine circovirus from 1996 to 2023 Open
Background Canine circovirus (CanineCV), a non-enveloped virus with a circular DNA genome, has been identified in various avian and mammalian species, including domestic and wild canids. This study aimed to comprehensively analyze the prev…
View article: The causal relationship between anti-diabetic drugs and gastrointestinal disorders: a drug-targeted mendelian randomization study
The causal relationship between anti-diabetic drugs and gastrointestinal disorders: a drug-targeted mendelian randomization study Open
View article: Author response: Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation
Author response: Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation Open
View article: Immune cell patterns before and after neoadjuvant immune checkpoint blockade combined with chemoradiotherapy in locally advanced esophageal squamous cell carcinoma
Immune cell patterns before and after neoadjuvant immune checkpoint blockade combined with chemoradiotherapy in locally advanced esophageal squamous cell carcinoma Open