Tiegui Nan
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View article: Hinokiflavone alleviates high-fat diet-induced erectile dysfunction via the EGFR/PI3K/Akt/eNOS signaling pathway
Hinokiflavone alleviates high-fat diet-induced erectile dysfunction via the EGFR/PI3K/Akt/eNOS signaling pathway Open
Background Erectile dysfunction (ED) is a significant health issue affecting the global male population, with a complex and multifaceted etiology. High-fat diet (HFD) is known to impair endothelial function and promote the development of E…
View article: Daidzin from Pueraria thomsonii regulate root plasticity and cell proliferation
Daidzin from Pueraria thomsonii regulate root plasticity and cell proliferation Open
View article: The Immune Regulation of Melanin From <i>Gallus gallus domesticus</i> Brisson Against Cyclophosphamide‐Induced Immunosuppression
The Immune Regulation of Melanin From <i>Gallus gallus domesticus</i> Brisson Against Cyclophosphamide‐Induced Immunosuppression Open
Black‐bone silky fowl ( Gallus gallus domesticus Brisson), medicinal food homology, utilizes to enhance human immunity. However, it remains unclear whether Black‐bone silky fowl melanin (BSFM), one of its bioactive components, could affect…
View article: Climate change impacts on spatiotemporal variability of soybean water demands in North China Plain
Climate change impacts on spatiotemporal variability of soybean water demands in North China Plain Open
Climate change has been acknowledged as one of the greatest challenges for agricultural production and water management globally. This study investigates the trends and spatial distribution of the water demands of soybean (Glycine max (L.)…
View article: Indigenous lignocellulose-degrading consortium efficiently degrade Traditional Chinese medicine residues
Indigenous lignocellulose-degrading consortium efficiently degrade Traditional Chinese medicine residues Open
View article: Characteristics and functions of volatile organic compounds in the tripartite symbiotic system of <i>Gastrodia elata-Armillaria gallica-Rahnella aceris</i> HPDA25
Characteristics and functions of volatile organic compounds in the tripartite symbiotic system of <i>Gastrodia elata-Armillaria gallica-Rahnella aceris</i> HPDA25 Open
Tripartite interactions among plants, fungi, and bacteria are critical for maintaining plant growth and fitness, and volatile organic compounds (VOCs) play a significant role in these interactions. However, the functions of VOCs within the…
View article: Blocking TSP1 Ameliorates Diabetes Mellitus-Induced Erectile Dysfunction by Inhibiting the TGF-β/SMAD Pathway
Blocking TSP1 Ameliorates Diabetes Mellitus-Induced Erectile Dysfunction by Inhibiting the TGF-β/SMAD Pathway Open
TSP1 expression is increased in the CC of DMED rats. HG-induced TSP1 secretion via autocrine signaling from CCSMCs and/or paracrine signaling from CCFs to accelerate penile fibrosis. LSKL, an antagonist of TSP1, could improve erectile dysf…
View article: Genome-wide identification of Glycyrrhiza uralensis Fisch. MAPK gene family and expression analysis under salt stress relieved by Bacillus subtilis
Genome-wide identification of Glycyrrhiza uralensis Fisch. MAPK gene family and expression analysis under salt stress relieved by Bacillus subtilis Open
Introduction: Research on Glycyrrhiza uralensis , a nonhalophyte that thrives in saline–alkaline soil and a traditional Chinese medicinal component, is focused on improving its ability to tolerate salt stress to increase its productivity a…
View article: Genome-wide identification of Glycyrrhiza uralensis Fisch. WRKY Gene family and expression analysis under salt stress
Genome-wide identification of Glycyrrhiza uralensis Fisch. WRKY Gene family and expression analysis under salt stress Open
WRKY is one of the largest transcription factor families in higher plants, playing a crucial role in plant growth, development, and responses to environmental stresses by binding to the W-box motif in the target gene promoters. Glycyrrhiza…
View article: Comparisons of wild and cultivated American ginseng (<i>Panax quinquefolius</i> L.) genomes provide insights into changes in root growth and metabolism during domestication
Comparisons of wild and cultivated American ginseng (<i>Panax quinquefolius</i> L.) genomes provide insights into changes in root growth and metabolism during domestication Open
American ginseng (Panax quinquefolius L.) originated in the forests of North America and was introduced to China over 40 years ago. Cultivated P. quinquefolius in China had fewer lateral roots and significantly decreased ginsenoside Rg1 co…
View article: An evaluation of Astragali Radix with different growth patterns and years, based on a new multidimensional comparison method
An evaluation of Astragali Radix with different growth patterns and years, based on a new multidimensional comparison method Open
Introduction With the depletion of wild Astragali Radix (WA) resources, imitated-wild Astragali Radix (IWA) and cultivated Astragali Radix (CA) have become the main products of Astragali Radix. However, the quality differences of three gro…
View article: Identification and Classification of Coix seed Storage Years Based on Hyperspectral Imaging Technology Combined with Deep Learning
Identification and Classification of Coix seed Storage Years Based on Hyperspectral Imaging Technology Combined with Deep Learning Open
Developing a fast and non-destructive methodology to identify the storage years of Coix seed is important in safeguarding consumer well-being. This study employed the utilization of hyperspectral imaging (HSI) in conjunction with conventio…
View article: New Evidence for Artemisia absinthium as an Alternative to Classical Antibiotics: Chemical Analysis of Phenolic Compounds, Screening for Antimicrobial Activity
New Evidence for Artemisia absinthium as an Alternative to Classical Antibiotics: Chemical Analysis of Phenolic Compounds, Screening for Antimicrobial Activity Open
Artemisia absinthium, an important herb of the Artemisia genus, was evaluated in this study for its potential as an alternative to classical antibiotics. The antimicrobial activity of methanol extracts of A. absinthium (MEAA) was evaluated…
View article: Rapid and Nondestructive Identification of Origin and Index Component Contents of Tiegun Yam Based on Hyperspectral Imaging and Chemometric Method
Rapid and Nondestructive Identification of Origin and Index Component Contents of Tiegun Yam Based on Hyperspectral Imaging and Chemometric Method Open
Tiegun yam is a typical food and medicine agricultural product, which has the effects of nourishing the kidney and benefitting the lungs. The quality and price of Tiegun yam are affected by its origin, and counterfeiting and adulteration a…
View article: Transcriptome analysis highlights the role of ferroptosis in palmitic acid–induced endothelial dysfunction
Transcriptome analysis highlights the role of ferroptosis in palmitic acid–induced endothelial dysfunction Open
Background Palmitic acid (PA) has a lipotoxic effect on blood vessels, leading to endothelial dysfunction and cell death. The underlying mechanisms are not yet fully understood. Aim We sought to investigate the effects of PA on endothelial…
View article: Prediction of chemical indicators for quality of Zanthoxylum spices from multi-regions using hyperspectral imaging combined with chemometrics
Prediction of chemical indicators for quality of Zanthoxylum spices from multi-regions using hyperspectral imaging combined with chemometrics Open
Fruits of Zanthoxylum bungeanum Maxim (Red “Huajiao,” RHJ) and Z. schinifolium Sieb. et Zucc. (Green “Huajiao,” GHJ) are famous spices around the world. Antioxidant capability (AOC), total alkylamides content (TALC) and volatile oil conten…
View article: Nutrient content prediction and geographical origin identification of red raspberry fruits by combining hyperspectral imaging with chemometrics
Nutrient content prediction and geographical origin identification of red raspberry fruits by combining hyperspectral imaging with chemometrics Open
The geographical origin and the important nutrient contents greatly affect the quality of red raspberry (RRB, Rubus idaeus L.), a popular fruit with various health benefits. In this study, a chemometrics-assisted hyperspectral imaging (HSI…
View article: A Mycorrhizal Bacteria Strain Isolated From Polyporus umbellatus Exhibits Broad-Spectrum Antifungal Activity
A Mycorrhizal Bacteria Strain Isolated From Polyporus umbellatus Exhibits Broad-Spectrum Antifungal Activity Open
The microbes in the rhizosphere (or mycorrhizosphere) could promote plant growth, however, it is unclear whether mycorrhizosphere microbes could fight multiple fungal pathogens. In this study, twenty-one bacterial strains distributed in 6 …
View article: Rapid Identification of Fupenzi (Rubus chingii Hu) and Its Adulteration by AuNP Visualization
Rapid Identification of Fupenzi (Rubus chingii Hu) and Its Adulteration by AuNP Visualization Open
Fupenzi (Rubus chingii Hu) is a dried and immature fruit in East China, which has effects of nourishing kidneys, solidifying essence, and otherwise. Because Fupenzi was often adulterated and replaced with inferior things, this paper had re…
View article: Practical Protocol for Comprehensively Evaluating Sulfur-Fumigation of Baizhi Based on Metabolomics, Pharmacology, and Cytotoxicity
Practical Protocol for Comprehensively Evaluating Sulfur-Fumigation of Baizhi Based on Metabolomics, Pharmacology, and Cytotoxicity Open
Sulfur Angelicae Dahuricae Radix (Baizhi) is a common medicinal herb in Asian countries. A practical protocol combining metabolomics, pharmacology, and cytotoxicity was developed to comprehensively evaluate the influence of sulfur-fumigati…
View article: Skimmed Bovine Milk-Derived Extracellular Vesicles Isolated via “Salting-Out”: Characterizations and Potential Functions as Nanocarriers
Skimmed Bovine Milk-Derived Extracellular Vesicles Isolated via “Salting-Out”: Characterizations and Potential Functions as Nanocarriers Open
Bovine milk-derived extracellular vesicles (BM-EVs) are recognized as promising nanoscale delivery vectors owing to their large availability. However, few isolation methods can achieve high purity and yield simultaneously. Therefore, we de…
View article: Chemical Profiling and Bioactivity Reveal the Pharmaceutical Properties of Two Species of <i>Radix Puerariae</i>
Chemical Profiling and Bioactivity Reveal the Pharmaceutical Properties of Two Species of <i>Radix Puerariae</i> Open
View article: Pharmacokinetics and Metabolites of Glycosides and Lignans of the Stem Bark of <i>Magnolia officinalis</i> in Functional Dyspepsia and Normal Rats Using LC-MS/MS
Pharmacokinetics and Metabolites of Glycosides and Lignans of the Stem Bark of <i>Magnolia officinalis</i> in Functional Dyspepsia and Normal Rats Using LC-MS/MS Open
View article: Development of an Enzyme-Linked Immunosorbent Assay Method for the Detection of Rhein in <i>Rheum officinale</i>
Development of an Enzyme-Linked Immunosorbent Assay Method for the Detection of Rhein in <i>Rheum officinale</i> Open
Rhein is an important quality-control marker of Rheum officinale . The aim of this study was to develop an indirect competitive enzyme-linked immunosorbent assay (icELISA) for rhein detection, which acts as a powerful tool for quality cont…
View article: Metabolome and transcriptome analyses reveal quality change in the orange-rooted Salvia miltiorrhiza (Danshen) from cultivated field
Metabolome and transcriptome analyses reveal quality change in the orange-rooted Salvia miltiorrhiza (Danshen) from cultivated field Open
View article: MOESM3 of Metabolome and transcriptome analyses reveal quality change in the orange-rooted Salvia miltiorrhiza (Danshen) from cultivated field
MOESM3 of Metabolome and transcriptome analyses reveal quality change in the orange-rooted Salvia miltiorrhiza (Danshen) from cultivated field Open
Additional file 3. Gene sequences of 104 significantly differentially expressed genes in normal and orange Danshen (with padjâ <â 0.05).
View article: The Gastrodia elata genome provides insights into plant adaptation to heterotrophy
The Gastrodia elata genome provides insights into plant adaptation to heterotrophy Open
View article: Cellular and Subcellular Immunohistochemical Localization and Quantification of Cadmium Ions in Wheat (Triticum aestivum)
Cellular and Subcellular Immunohistochemical Localization and Quantification of Cadmium Ions in Wheat (Triticum aestivum) Open
The distribution of metallic ions in plant tissues is associated with their toxicity and is important for understanding mechanisms of toxicity tolerance. A quantitative histochemical method can help advance knowledge of cellular and subcel…