Tieying Hou
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View article: 169 Use of fine needle aspiration supernatant from lung carcinoma for PCR sequencing: does the collecting medium make a difference?
169 Use of fine needle aspiration supernatant from lung carcinoma for PCR sequencing: does the collecting medium make a difference? Open
Introduction/Objective The emergence of personalized treatment and molecular sequencing has transformed the management of advanced non-small-cell lung carcinoma (NSCLC). Cytologic samples are a reliable source of DNA for molecular testing,…
View article: Late Recurrence/Metastasis of Acinic Cell Carcinoma After 10 Years of Resection: A Case Series and Literature Review
Late Recurrence/Metastasis of Acinic Cell Carcinoma After 10 Years of Resection: A Case Series and Literature Review Open
Background: Acinic cell carcinoma (AciCC) is a relatively rare malignancy of the salivary glands, predominantly affecting the parotid gland. Recent studies report that the local recurrence rate for AciCC ranges from 5% to 17%, while metast…
View article: Low Uptake of Primary HPV Screening: One-Year Experience with the BD Onclarity™ Assay
Low Uptake of Primary HPV Screening: One-Year Experience with the BD Onclarity™ Assay Open
View article: Repurposing Etalocib suppresses multidrug-resistant Staphylococcus aureus by disrupting the bacterial membrane
Repurposing Etalocib suppresses multidrug-resistant Staphylococcus aureus by disrupting the bacterial membrane Open
View article: Repurposing AZD-5991 for inhibiting growth and biofilm formation of Staphylococcus aureus by disrupting the cell membrane and targeting FabI
Repurposing AZD-5991 for inhibiting growth and biofilm formation of Staphylococcus aureus by disrupting the cell membrane and targeting FabI Open
View article: Remote Recurrence/Metastasis of Acinic Cell Carcinoma: a Case Series and Literature Review
Remote Recurrence/Metastasis of Acinic Cell Carcinoma: a Case Series and Literature Review Open
Background:Acinic cell carcinoma (ACC) is a relatively indolent salivary gland tumor with recurrence usually occurring within the first five years after the primary resection. Delayed recurrence/metastasis after more than 10 years is rare …
View article: Non‐Invasive Follicular Thyroid Neoplasm With Papillary‐Like Nuclear Features (<scp>NIFTPs</scp>)
Non‐Invasive Follicular Thyroid Neoplasm With Papillary‐Like Nuclear Features (<span>NIFTPs</span>) Open
Over the past few years, follicular‐patterned thyroid nodules with nuclear features of papillary thyroid carcinoma (PTC) have been further subclassified based on molecular profiling, histologic features, and clinical behavior. Non‐invasive…
View article: Repurposing AZD-5991 for inhibiting growth and biofilm formation of <i>Staphylococcus aureus</i> by disrupting the cell membrane and targeting FabI
Repurposing AZD-5991 for inhibiting growth and biofilm formation of <i>Staphylococcus aureus</i> by disrupting the cell membrane and targeting FabI Open
Staphylococcus aureus infections have already become a major threat to public health worldwide. Drug resistance and biofilm formation are two critical factors that significantly affect the efficacy of the antimicrobial treatment of S. aure…
View article: Cytomorphology and clinicopathologic correlation of TFE3‐rearranged renal cell carcinoma
Cytomorphology and clinicopathologic correlation of TFE3‐rearranged renal cell carcinoma Open
Background TFE3 ‐rearranged renal cell carcinoma ( TFE3 ‐rRCC) harbors gene fusions involving TFE3 with one of many different partner genes. Because of their diverse morphologies, the differential diagnosis is broad and challenging. Public…
View article: Inhibition of Growth and Biofilm Formation in Staphylococcus aureus by LLY-507
Inhibition of Growth and Biofilm Formation in Staphylococcus aureus by LLY-507 Open
The emergence of methicillin-resistant Staphylococcus aureus (MRSA) as a prevalent antibiotic-resistant pathogen underscores the urgent need for novel antibacterial agents. This study investigates the potential of LLY-507 against gram-posi…
View article: Antibacterial activity and mechanisms of D-3263 against Staphylococcus aureus
Antibacterial activity and mechanisms of D-3263 against Staphylococcus aureus Open
Multi-drug-resistant Staphylococcus aureus infections necessitate novel antibiotic development. D-3263, a transient receptor potential melastatin member 8 (TRPM8) agonist, has potential antineoplastic properties. Here, we reported the anti…
View article: Invasive Fungal Infections of the Head and Neck: A Tertiary Hospital Experience
Invasive Fungal Infections of the Head and Neck: A Tertiary Hospital Experience Open
From the existing millions of fungal species, only a few cause disease. In this study, we investigated invasive fungal infections in the head and neck (H&N) over a 19-year period (2005 to 2024) at a large academic healthcare system. Among …
View article: Invasive Fungal Infections of the Head & Neck: A Tertiary Hospital Experience
Invasive Fungal Infections of the Head & Neck: A Tertiary Hospital Experience Open
From the existing millions of fungal species only a few cause disease. In this study, we investigated invasive fungal infections in the head and neck over a 19-year period (2005 to 2024) at a large academic healthcare system. Among 413 cas…
View article: Metastatic germ cell tumors in serous cavities and cerebrospinal fluid: A single‐center experience
Metastatic germ cell tumors in serous cavities and cerebrospinal fluid: A single‐center experience Open
Background Metastatic germ cell tumors (GCTs) involving body cavity effusions and cerebrospinal fluid (CSF) are rare. Diagnosis is challenging because of limited morphological and clinicopathological information in the literature. Methods …
View article: Head and neck Cytopathology: Options for high-risk HPV testing in head and neck FNA specimens, a concise review
Head and neck Cytopathology: Options for high-risk HPV testing in head and neck FNA specimens, a concise review Open
High-risk human papillomavirus (HR-HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) is a unique form of head and neck cancer with distinct biology and better prognosis than conventional SCC. Many patients with HR-HPV positive …
View article: Developing Cell Surface Target Discovery Pipeline in Metastatic Thymic Epithelial Tumors (mTET)
Developing Cell Surface Target Discovery Pipeline in Metastatic Thymic Epithelial Tumors (mTET) Open
View article: AB025. Evaluation of potential therapeutic immunohistochemical targets with experimental or FDA-approved therapies in thymic epithelial tumor microarrays
AB025. Evaluation of potential therapeutic immunohistochemical targets with experimental or FDA-approved therapies in thymic epithelial tumor microarrays Open
Background:\nThymus epithelial tumors (TETs) are rare malignancies of the anterior mediastinum. The current standard of care for metastatic TETs is a combination of platinum-based chemotherapy. Here, we have evaluated the experimental and …
View article: Inflammatory pseudotumor of frontal sinus mimicking an aggressive malignancy: a rare case with diagnostic challenge on fine needle aspiration
Inflammatory pseudotumor of frontal sinus mimicking an aggressive malignancy: a rare case with diagnostic challenge on fine needle aspiration Open
Introduction/Objective Inflammatory pseudotumor (IPT) of sinonasal tract is a rare disease that sometimes mimicks malignancy in radiographic findings. Diagnosis of IPT on fine needle aspiration (FNA) is challenging due to limited cellulari…
View article: Fine needle aspiration cytology of metastatic tumors to the thyroid: a 20-years single institution retrospective study
Fine needle aspiration cytology of metastatic tumors to the thyroid: a 20-years single institution retrospective study Open
Introduction/Objective Metastases to the thyroid are rare and represent approximately 2% to 3% of all thyroid malignancies. In this study we aim to report our institution experience with these tumors over the last twenty years. Methods/Cas…
View article: Pleomorphic Adenoma With Cystic Change, Extensive Squamous Metaplasia and Positive Block-Like p16 Staining Pattern: A Sheep In Wolf’s Clothing
Pleomorphic Adenoma With Cystic Change, Extensive Squamous Metaplasia and Positive Block-Like p16 Staining Pattern: A Sheep In Wolf’s Clothing Open
Introduction/Objective Pleomorphic adenoma, the most common benign salivary gland neoplasm may show squamous metaplasia in up to 25% of cases, and less frequent cystic change. We report an unusual case of pleomorphic adenoma with cystic ch…
View article: EP03.04-02 Evaluation of Potential Therapeutic Targets with Experimental or FDA-approved Therapies in Thymic Tumor Microarrays
EP03.04-02 Evaluation of Potential Therapeutic Targets with Experimental or FDA-approved Therapies in Thymic Tumor Microarrays Open
View article: SiGra: single-cell spatial elucidation through an image-augmented graph transformer
SiGra: single-cell spatial elucidation through an image-augmented graph transformer Open
View article: Amyloid Deposition in the Upper Aerodigestive Tract, A Single Institute Experience
Amyloid Deposition in the Upper Aerodigestive Tract, A Single Institute Experience Open
Objectives: The purpose of this study is to evaluate clinical information, laboratory results, and pathologic findings of patients with amyloidosis involving larynx, oral cavity, and pharynx from our institute. Methods: A total of 39 speci…
View article: Histology shift in esophageal cancer between biopsies and resections after neoadjuvant therapy: a pilot study
Histology shift in esophageal cancer between biopsies and resections after neoadjuvant therapy: a pilot study Open
Background Preoperative neoadjuvant therapy followed by resection is the mainstay treatment for locally advanced esophageal adenocarcinoma (EAC). We recently observed the histology shift from predominant EAC in the biopsy to neuroendocrine…
View article: Multifocal C-cell Hyperplasia and Marked Hypercalcitoninemia in a Diabetic Patient Treated With Glucagon-Like Peptide-1 Agonist With Concurrent Multinodular Goiter and Hyperparathyroidism
Multifocal C-cell Hyperplasia and Marked Hypercalcitoninemia in a Diabetic Patient Treated With Glucagon-Like Peptide-1 Agonist With Concurrent Multinodular Goiter and Hyperparathyroidism Open
View article: Embryonal rhabdomyosarcoma of oropharynx in a 65-year-old male with indolent clinical presentation and unusual morphology
Embryonal rhabdomyosarcoma of oropharynx in a 65-year-old male with indolent clinical presentation and unusual morphology Open
Introduction/Objective Embryonal rhabdomyosarcoma (ERMS) is a malignant primitive mesenchymal tumor which commonly affects children and adolescence. Although head and neck area is a common location for ERMS, oropharynx is rarely involved. …
View article: Morphologic Changes in the Thymus Following Chemotherapy for Anterior Mediastinal Germ Cell Tumors: A Study of 91 Cases Emphasizing Pseudoneoplastic Features
Morphologic Changes in the Thymus Following Chemotherapy for Anterior Mediastinal Germ Cell Tumors: A Study of 91 Cases Emphasizing Pseudoneoplastic Features Open
Context.— The interpretation of postchemotherapy resections of anterior mediastinal germ cell tumors plays a critical role in determining future patient management and prognosis. Treatment-related changes in the thymus may mimic residual t…
View article: Isolated Kaposi sarcoma of the upper aerodigestive tract in immunocompetent individuals, an underrecognized entity with favorable prognosis
Isolated Kaposi sarcoma of the upper aerodigestive tract in immunocompetent individuals, an underrecognized entity with favorable prognosis Open
Kaposi sarcoma (KS) is a rare vascular neoplasm that most commonly arises in the setting of immunosuppression, in areas with high prevalence of Human Herpesvirus-8 infection, and when both situations coexist. Most cases affect the skin, is…
View article: Mass-forming chronic invasive fungal sinusitis; an uncommon mimicker of head & neck malignancy
Mass-forming chronic invasive fungal sinusitis; an uncommon mimicker of head & neck malignancy Open
Introduction/Objective Invasive fungal sinusitis is a progressive infection affecting the nasal cavity and associated sinus spaces. Acute forms affect immunocompromised patients with debilitating systemic diseases while chronic forms usual…
View article: Amyloid deposition in oral cavity and larynx, a single institute experience
Amyloid deposition in oral cavity and larynx, a single institute experience Open
Introduction/Objective Amyloidosis is characterized by extracellular accumulation of insoluble amyloid fibril. Amyloid deposition in the head and neck area is rare. Methods/Case Report In this study, we reviewed 34 specimens from 26 patien…