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View article: Changes in patient characteristics and procedural measures over a 10-year period in aortic valve-in-valve procedures for degenerated surgical bioprostheses
Changes in patient characteristics and procedural measures over a 10-year period in aortic valve-in-valve procedures for degenerated surgical bioprostheses Open
Objectives Aortic valve-in-valve procedures for treatment of degenerated surgical bioprostheses are an established therapy. In this study, we evaluated how the risk profiles, procedural approaches, and early outcomes for patients in these …
View article: Percutaneous Cannulation for Minimally Invasive Heart Valve Surgery: Results from a Multicenter Registry
Percutaneous Cannulation for Minimally Invasive Heart Valve Surgery: Results from a Multicenter Registry Open
Objective To avoid potential groin incision associated complications and further streamline surgery percutaneous femoral cannulation using different vascular closure devices (VCDs) has emerged to establish cardiopulmonary bypass during min…
View article: Complicated acute type A aortic dissection and severe aortic atherosclerosis predict early mortality after frozen elephant trunk procedure
Complicated acute type A aortic dissection and severe aortic atherosclerosis predict early mortality after frozen elephant trunk procedure Open
OBJECTIVES To analyse risk factors for early mortality and long-term survival including secondary distal aortic interventions in patients undergoing frozen elephant trunk surgery. METHODS A retrospective single-centre study was conducted, …
View article: Preoperative Mechanical Ventilation Prior to Surgical Repair for Type A Aortic Dissection: Incidence, Risk, and Outcomes
Preoperative Mechanical Ventilation Prior to Surgical Repair for Type A Aortic Dissection: Incidence, Risk, and Outcomes Open
Objectives: Several conditions associated with type A aortic dissection may require preoperative invasive mechanical ventilation (IMV). The current literature lacks data on this subset of patients’ prevalence and postoperative outcomes. Th…
View article: Extent of coronary artery disease and clinical outcomes with ticagrelor monotherapy versus aspirin after coronary artery bypass grafting: insights from the TiCAB trial
Extent of coronary artery disease and clinical outcomes with ticagrelor monotherapy versus aspirin after coronary artery bypass grafting: insights from the TiCAB trial Open
OBJECTIVES Patients with extensive coronary artery disease (CAD) have a higher risk of cardiovascular events. This post hoc analysis of the Ticagrelor in CABG (TiCAB) trial examined the association of ticagrelor monotherapy versus aspirin …
View article: Coronary artery bypass grafting using both internal mammary arteries—a safe concept for surgical training
Coronary artery bypass grafting using both internal mammary arteries—a safe concept for surgical training Open
OBJECTIVES In our centre, a bilateral internal mammary artery first approach is established from day 1 of surgical training. We herein aimed to investigate safety and clinical efficacy of this training concept. METHODS All patients undergo…
View article: Extent of surgical repair and outcomes after surgery for type A aortic dissection
Extent of surgical repair and outcomes after surgery for type A aortic dissection Open
Background Acute Stanford type A aortic dissection is a severe emergency condition that, if left untreated, is associated with a high mortality rate. The extent of surgical repair may impact the outcomes of these patients. Method Patients …
View article: Ascending aortic replacement versus aortic root replacement in patients with type A aortic dissection involving the aortic root
Ascending aortic replacement versus aortic root replacement in patients with type A aortic dissection involving the aortic root Open
Background: Extensive surgical resection of the thoracic aorta in patients with type A aortic dissection (TAAD) is thought to reduce the risk of late aortic wall degeneration and the need for repeat aortic operations. Objectives: We evalua…
View article: Carotid artery dissection and neurological complications after surgery for type 1 aortic dissection
Carotid artery dissection and neurological complications after surgery for type 1 aortic dissection Open
Background Data on the prognostic impact of type A aortic dissection involving the common carotid arteries (CCAs) are scarce. Methods Data on the status of the CCAs were available in 1106 patients who underwent surgery for acute DeBakey ty…
View article: The David Versus the Bentall Procedure for Acute Type A Aortic Dissection
The David Versus the Bentall Procedure for Acute Type A Aortic Dissection Open
Background: Type A aortic dissection (TAAD) is a life-threatening condition which requires prompt diagnosis and surgical treatment. When TAAD involves the aortic root, aortic valve-sparing or Bentall procedures are the main surgical treatm…
View article: Malperfusion syndrome in patients undergoing repair for acute type A aortic dissection: Presentation, mortality, and utility of the Penn classification
Malperfusion syndrome in patients undergoing repair for acute type A aortic dissection: Presentation, mortality, and utility of the Penn classification Open
Nearly one half of the examined cohort presented with signs of malperfusion syndrome predominantly attributable to local involvement. More than one third of patients with local malperfusion syndrome had a multivessel involvement. Furthermo…
View article: Survival after surgery for acute type A aortic dissection in octogenarians
Survival after surgery for acute type A aortic dissection in octogenarians Open
Provided a thoughtful patient selection, surgery may provide a survival benefit in patients aged ≥ 80 years with ATAAD that, when compared to younger patients and the general population, may last up to 5 years after the procedure. These fi…
View article: Late diagnosis of Marfan syndrome is associated with unplanned aortic surgery and cardiovascular death
Late diagnosis of Marfan syndrome is associated with unplanned aortic surgery and cardiovascular death Open
Late diagnosis of MFS is associated with delayed surgery and death.
View article: Role of gender in short- and long-term outcomes after surgery for type A aortic dissection: analysis of a multicentre European registry
Role of gender in short- and long-term outcomes after surgery for type A aortic dissection: analysis of a multicentre European registry Open
OBJECTIVES Gender difference in the outcome after type A aortic dissection (TAAD) surgery remains an issue of ongoing debate. In this study, we aimed to evaluate the impact of gender on the short- and long-term outcome after surgery for TA…
View article: Aortic arch surgery for DeBakey type 1 aortic dissection in patients aged 60 years or younger
Aortic arch surgery for DeBakey type 1 aortic dissection in patients aged 60 years or younger Open
Background Extended aortic repair is considered a key issue for the long-term durability of surgery for DeBakey type 1 aortic dissection. The risk of aortic degeneration may be higher in young patients due to their long life expectancy. Th…
View article: Late diagnosis of Marfan syndrome is associated with unplanned aortic surgery and cardiovascular death
Late diagnosis of Marfan syndrome is associated with unplanned aortic surgery and cardiovascular death Open
Background Marfan syndrome (MFS) guidelines recommend optimal pharmacological therapy (OPT) and replacement of the ascending aorta (RAA) at 5.0cm diameters to prevent acute type A aortic dissection (ATAAD) and death. The effect of early MF…
View article: Transcatheter aortic valve implantation in patients with significant septal hypertrophy
Transcatheter aortic valve implantation in patients with significant septal hypertrophy Open
Background Previous reports suggest septal hypertrophy with an interventricular septum depth (IVSD) ≥ 14 mm may adversely affect outcomes after transcatheter aortic valve implantation (TAVI) due to suboptimal valve placement, valve migrati…
View article: Intravascular Lithotripsy-Assisted Transfemoral Transcatheter Aortic Valve Implantation in Patients with Severe Iliofemoral Calcifications: Expanding Transfemoral Indications
Intravascular Lithotripsy-Assisted Transfemoral Transcatheter Aortic Valve Implantation in Patients with Severe Iliofemoral Calcifications: Expanding Transfemoral Indications Open
(1) Background: Transfemoral transcatheter aortic valve implantation (TAVI) has become the standard treatment for most patients with severe symptomatic aortic stenosis. Intravascular lithotripsy may facilitate transfemoral TAVI (IVL-TAVI) …
View article: Baseline risk factors of in-hospital mortality after surgery for acute type A aortic dissection: an ERTAAD study
Baseline risk factors of in-hospital mortality after surgery for acute type A aortic dissection: an ERTAAD study Open
Background Surgery for type A aortic dissection (TAAD) is associated with high risk of mortality. Current risk scoring methods have a limited predictive accuracy. Methods Subjects were patients who underwent surgery for acute TAAD at 18 Eu…
View article: In memoriam: Prof. Dr. rer. nat. Jeanette Erdmann
In memoriam: Prof. Dr. rer. nat. Jeanette Erdmann Open
Prof. Dr. Jeanette Erdmann, a distinguished cardiovascular geneticist who served as Professor at the Institute of Cardiogenetics at the University of Lübeck and at the German Center for Cardiovascular Research (DZHK), passed away suddenly …
View article: Impact of age versus comorbidities on outcomes after transcatheter aortic valve implantation: validating the guideline-recommended age cut-off
Impact of age versus comorbidities on outcomes after transcatheter aortic valve implantation: validating the guideline-recommended age cut-off Open
Background Transcatheter aortic valve implantation (TAVI) has become the most common treatment for patients with severe aortic stenosis (AS) in Europe and North America. Current European guidelines recommend transfemoral TAVI for patients …
View article: Preoperative arterial lactate and outcome after surgery for type A aortic dissection: The ERTAAD multicenter study
Preoperative arterial lactate and outcome after surgery for type A aortic dissection: The ERTAAD multicenter study Open
Hyperlactatemia significantly increased the risk of mortality after surgery for acute TAAD and should be considered in the clinical assessment of these critically ill patients.
View article: Valve-in-valve procedures for degenerated surgical and transcatheter aortic valve bioprostheses using a latest-generation self-expanding intra-annular transcatheter heart valve
Valve-in-valve procedures for degenerated surgical and transcatheter aortic valve bioprostheses using a latest-generation self-expanding intra-annular transcatheter heart valve Open
Background Valve-in-valve (ViV) transfemoral transcatheter aortic valve implantation (TAVI) for failing aortic surgical bioprostheses or transcatheter heart valves (THV) has demonstrated a reasonable clinical and hemodynamic efficacy. Trad…
View article: Analysing debranching techniques in Frozen Elephant Trunk procedures: a narrative literature review
Analysing debranching techniques in Frozen Elephant Trunk procedures: a narrative literature review Open
There is an improved numeric outcome of different debranching techniques with proximalization of the distal anastomosis, but without reaching statistical significance. This review shows marked heterogeneity across included studies and high…
View article: Interinstitutional analysis of the outcome after surgery for type A aortic dissection
Interinstitutional analysis of the outcome after surgery for type A aortic dissection Open
View article: Temporal changes of patient characteristics over 12 years in a single-center transcatheter aortic valve implantation cohort
Temporal changes of patient characteristics over 12 years in a single-center transcatheter aortic valve implantation cohort Open
View article: Prognostic impact and diagnostic value of invasively derived hemodynamic measures in patients with severe aortic stenosis undergoing TAVI
Prognostic impact and diagnostic value of invasively derived hemodynamic measures in patients with severe aortic stenosis undergoing TAVI Open
View article: Outcome after Surgery for Iatrogenic Acute Type A Aortic Dissection
Outcome after Surgery for Iatrogenic Acute Type A Aortic Dissection Open
(1) Background: Acute Stanford type A aortic dissection (TAAD) may complicate the outcome of cardiovascular procedures. Data on the outcome after surgery for iatrogenic acute TAAD is scarce. (2) Methods: The European Registry of Type A Aor…
View article: Risk factors for impaired neurological outcome after thoracic aortic surgery
Risk factors for impaired neurological outcome after thoracic aortic surgery Open
Identified independent risk factors for all strokes were advanced age, ATAD, arch surgery, concomitant CABG, and high ECC time. Hemodynamic and embolic strokes show distinct risk profiles.
View article: Expanding the clinical spectrum of COL2A1 related disorders by a mass like phenotype
Expanding the clinical spectrum of COL2A1 related disorders by a mass like phenotype Open
MASS phenotype is a connective tissue disorder clinically overlapping with Marfan syndrome and caused by pathogenic variants in FBN1 . We report four patients from three families presenting with a MASS-like phenotype consisting of tall sta…