Tilman Walker
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View article: Development of a simple clinical score to estimate in-hospital adverse event risk after elective hip arthroplasty: a retrospective cohort study in a high-risk population
Development of a simple clinical score to estimate in-hospital adverse event risk after elective hip arthroplasty: a retrospective cohort study in a high-risk population Open
Introduction Patients undergoing total hip arthroplasty (THA) in tertiary centres often present with complex comorbidities that increase the risk of perioperative adverse events (AE). While fast-track and outpatient protocols are expanding…
View article: Osteogenic and angiogenic potential of molybdenum-containing mesoporous bioactive glass nanoparticles: An ionic approach to bone tissue engineering
Osteogenic and angiogenic potential of molybdenum-containing mesoporous bioactive glass nanoparticles: An ionic approach to bone tissue engineering Open
Biomaterials intended for application in bone tissue engineering (BTE) ideally stimulate osteogenesis and angiogenesis simultaneously, as both mechanisms are of critical importance for successful bone regeneration. Mesoporous bioactive gla…
View article: Boric acid and Molybdenum trioxide synergistically stimulate osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells
Boric acid and Molybdenum trioxide synergistically stimulate osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells Open
The combination of B and Mo might be beneficial for BTE applications since the limited osteogenic properties of B can be compensated by Mo. Furthermore, since B is known to be pro-angiogenic, the combination of both substances may synergis…
View article: Femoral revision in total hip arthroplasty using a cementless modular stem: clinical and radiological results with a 8-year follow-up
Femoral revision in total hip arthroplasty using a cementless modular stem: clinical and radiological results with a 8-year follow-up Open
Introduction Modular femoral components allow for patient-specific restoration of hip joint geometry and the reconstruction of extensive bone defects in revision total hip arthroplasty (THA); however, potential problems of modular implants…
View article: Impact of Comorbidities and Previous Surgery on Mid-Term Results of Revision Total Knee Arthroplasty for Periprosthetic Joint Infection
Impact of Comorbidities and Previous Surgery on Mid-Term Results of Revision Total Knee Arthroplasty for Periprosthetic Joint Infection Open
(1) Background: In the treatment of periprosthetic joint infection (PJI), the individual host status and previous surgical procedures appear to have a relevant influence on success rates and clinical outcome of knee revision surgery. Curre…
View article: Fixed‐bearing is superior to mobile‐bearing in lateral unicompartmental knee replacement: a retrospective matched‐pairs analysis
Fixed‐bearing is superior to mobile‐bearing in lateral unicompartmental knee replacement: a retrospective matched‐pairs analysis Open
Purpose Due to low incidence of isolated lateral osteoarthritis (OA), there are limited data on whether a fixed‐bearing (FB) or a mobile‐bearing (MB) design is superior for lateral unicompartmental knee replacement (UKR). The aim of this m…
View article: Clinical and Functional Results of Cementless Unicompartmental Knee Arthroplasty with a Minimum Follow Up of 5 Years—A Consecutive Cohort of 201 Patients
Clinical and Functional Results of Cementless Unicompartmental Knee Arthroplasty with a Minimum Follow Up of 5 Years—A Consecutive Cohort of 201 Patients Open
The number of unicompartmental knee replacements (UKR) is increasing. Alongside various advantages, the revision rate of cemented UKR is higher compared to total knee arthroplasty (TKR). In contrast, cementless fixation shows reduced revis…
View article: Physical Activity of Young Patients following Minimally Invasive Lateral Unicompartmental Knee Replacement
Physical Activity of Young Patients following Minimally Invasive Lateral Unicompartmental Knee Replacement Open
Unicompartmental knee replacement (UKR) has increased in popularity in recent years, especially in young patients with high demands on their athletic ability. To date, there are no data available on the physical activity of young patients …
View article: Mobile bearing versus fixed bearing medial unicompartmental knee replacement: an independent two center matched-pairs analysis
Mobile bearing versus fixed bearing medial unicompartmental knee replacement: an independent two center matched-pairs analysis Open
Introduction The aim of the present study was to compare clinical outcome between patients following fixed-bearing (FB) or mobile-bearing (MB) unicompartmental knee replacement (UKR) for antero-medial knee osteoarthrosis (OA) at two indepe…
View article: Infiltration Profile of Regulatory T Cells in Osteoarthritis-Related Pain and Disability
Infiltration Profile of Regulatory T Cells in Osteoarthritis-Related Pain and Disability Open
Emerging evidence indicates that regulatory T cells (Treg) intervene in the inflammatory processes that drive osteoarthritis (OA). However, whether polarized Tregs affect clinical features of the disease in the short- or long-term, and if …
View article: Bearing Thickness Is Not a Predictive Factor for Damage and Penetration in Oxford Unicompartmental Knee Arthroplasty—A Retrieval Analysis
Bearing Thickness Is Not a Predictive Factor for Damage and Penetration in Oxford Unicompartmental Knee Arthroplasty—A Retrieval Analysis Open
The medial Oxford unicompartmental knee arthroplasty (OUKA) shows good survivorship, as well as clinical results. Aseptic loosening, however, remains one of the main reasons for revision and polyethylene debris is known to cause aseptic lo…
View article: T Helper Cell Infiltration in Osteoarthritis-Related Knee Pain and Disability
T Helper Cell Infiltration in Osteoarthritis-Related Knee Pain and Disability Open
Despite the growing body of literature demonstrating a crucial role of T helper cell (Th) responses in the pathogenesis of osteoarthritis (OA), only few clinical studies have assessed interactions between Th cells and OA—related symptoms. …
View article: What Is the Long-term (27- to 32-year) Survivorship of an Uncemented Tapered Titanium Femoral Component and Survival in Patients Younger Than 50 Years?
What Is the Long-term (27- to 32-year) Survivorship of an Uncemented Tapered Titanium Femoral Component and Survival in Patients Younger Than 50 Years? Open
Background Uncemented femoral components in primary THA are in widespread use, especially in patients younger than 50 years, but few studies have evaluated their survival into the late third and early fourth decade. Questions/purposes We e…
View article: Significance of MEF2C and RUNX3 Regulation for Endochondral Differentiation of Human Mesenchymal Progenitor Cells
Significance of MEF2C and RUNX3 Regulation for Endochondral Differentiation of Human Mesenchymal Progenitor Cells Open
Guiding progenitor cell development between chondral versus endochondral pathways is still an unachieved task of cartilage neogenesis, and human mesenchymal progenitor cell (MPC) chondrogenesis is considered as a valuable model to better u…
View article: Synovial Cytokines Significantly Correlate with Osteoarthritis-Related Knee Pain and Disability: Inflammatory Mediators of Potential Clinical Relevance
Synovial Cytokines Significantly Correlate with Osteoarthritis-Related Knee Pain and Disability: Inflammatory Mediators of Potential Clinical Relevance Open
The aim of this study was to identify inflammatory mediators of potential clinical relevance in synovial fluid (SF) samples of patients with knee osteoarthritis (OA). Therefore, radiographic OA severity, knee pain and function of 34 OA pat…
View article: Cementless unicompartmental knee replacement allows early return to normal activity
Cementless unicompartmental knee replacement allows early return to normal activity Open
Patients recover rapidly after cementless OUKR with a return to sports rate of 100% and patients are able to participate in high impact sports disciplines.
View article: Results after Cementless Medial Oxford Unicompartmental Knee Replacement - Incidence of Radiolucent Lines
Results after Cementless Medial Oxford Unicompartmental Knee Replacement - Incidence of Radiolucent Lines Open
After cementless implantation RL were limited to the tibia, partial and never progressive. During short term follow-up the incidence of RL decreased significantly. RL seem to have no influence on clinical outcome and revision.