Tim Chang
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View article: Label-Free Analysis of Red Blood Cell Storage Lesions Using Imaging Flow Cytometry
Label-Free Analysis of Red Blood Cell Storage Lesions Using Imaging Flow Cytometry Open
Deleterious changes, collectively termed as storage lesions, alter the characteristics of red blood cell (RBC) morphology during in vitro storage. Due to gradual loss of cellular membrane, RBCs lose their original biconcave disk shape and …
View article: Label-Free Analysis of Red Blood Cell Storage Lesions Using Imaging Flow Cytometry
Label-Free Analysis of Red Blood Cell Storage Lesions Using Imaging Flow Cytometry Open
Deleterious changes, collectively termed as storage lesions, alter the characteristics of red blood cell (RBC) morphology during in vitro storage. Due to gradual loss of cellular membrane, RBCs lose their original biconcave disk shape and …
View article: Query-aware Multi-modal based Ranking Relevance in Video Search
Query-aware Multi-modal based Ranking Relevance in Video Search Open
Relevance ranking system plays a crucial role in video search on streaming platforms. Most relevance ranking methods focus on text modality, incapable of fully exploiting cross-modal cues present in video. Recent multi-modal models have de…
View article: ORANGE: Text-video Retrieval via Watch-time-aware Heterogeneous Graph Contrastive Learning
ORANGE: Text-video Retrieval via Watch-time-aware Heterogeneous Graph Contrastive Learning Open
Yucheng Lin, Tim Chang, Yaning Chang, Jianqiang Ma, Donghui Li, Ting Peng, Zang Li, Zhiyi Zhou, Feng Wang. Proceedings of the 2023 Conference on Empirical Methods in Natural Language Processing: Industry Track. 2023.
View article: Phenotypic analysis of erythrocytes in sickle cell disease using imaging flow cytometry
Phenotypic analysis of erythrocytes in sickle cell disease using imaging flow cytometry Open
The morphology and other phenotypic characteristics of erythrocytes in sickle cell disease (SCD) have been analyzed for decades in patient evaluation. This involves a variety of techniques, including microscopic analysis of stained blood f…
View article: Ultra-Low-Dose CT: An Effective Follow-Up Imaging Modality for Ureterolithiasis
Ultra-Low-Dose CT: An Effective Follow-Up Imaging Modality for Ureterolithiasis Open
Background and Purpose: Classically, abdominal X-ray (KUB), ultrasound, or a combination of both have been routinely used for ureteral stone surveillance after initial diagnosis. More recently, ultra-low-dose CT (ULD CT) has emerged as a C…
View article: Label‐Free Analysis of Red Blood Cell Storage Lesions Using Imaging Flow Cytometry
Label‐Free Analysis of Red Blood Cell Storage Lesions Using Imaging Flow Cytometry Open
Deleterious changes, collectively termed as storage lesions, alter the characteristics of red blood cell (RBC) morphology during in vitro storage. Due to gradual loss of cellular membrane, RBCs lose their original biconcave disk shape and …
View article: Multidimensional analysis of Gammaherpesvirus RNA expression reveals unexpected heterogeneity of gene expression
Multidimensional analysis of Gammaherpesvirus RNA expression reveals unexpected heterogeneity of gene expression Open
Virus-host interactions are frequently studied in bulk cell populations, obscuring cell-to-cell variation. Here we investigate endogenous herpesvirus gene expression at the single-cell level, combining a sensitive and robust fluorescent in…
View article: General methods for quantitative interpretation of results of digital variable-volume assays
General methods for quantitative interpretation of results of digital variable-volume assays Open
In digital assays, devices typically require precisely controlled volumes since variation can cause biases in concentration estimates. Here, we develop methods to correct bias when compartment volumes are variable.
View article: Multidimensional analysis of Gammaherpesvirus RNA expression reveals unexpected heterogeneity of gene expression
Multidimensional analysis of Gammaherpesvirus RNA expression reveals unexpected heterogeneity of gene expression Open
Virus-host interactions are frequently studied in bulk cell populations, obscuring cell-to-cell variation. Here we investigate endogenous herpesvirus gene expression at the single-cell level, combining a sensitive and robust fluorescent in…
View article: An open-chamber flow-focusing device for focal stimulation of micropatterned cells
An open-chamber flow-focusing device for focal stimulation of micropatterned cells Open
Microfluidic devices can deliver soluble factors to cell and tissue culture microenvironments with precise spatiotemporal control. However, enclosed microfluidic environments often have drawbacks such as the need for continuous culture med…