Tim Eckmanns
YOU?
Author Swipe
View article: Antibiotic consumption patterns in acute care hospitals: an integrated analysis using regression modelling combining data from two surveillance systems, Germany, 2022
Antibiotic consumption patterns in acute care hospitals: an integrated analysis using regression modelling combining data from two surveillance systems, Germany, 2022 Open
BACKGROUND To enhance antibiotic stewardship and effectively address antimicrobial resistance (AMR), better understanding of subnational antibiotic consumption patterns is essential. AIM We aimed to assess antibiotic consumption in Germany…
View article: The burden of bacterial antimicrobial resistance in the WHO Eastern Mediterranean Region 1990–2021: a cross-country systematic analysis with forecasts to 2050
The burden of bacterial antimicrobial resistance in the WHO Eastern Mediterranean Region 1990–2021: a cross-country systematic analysis with forecasts to 2050 Open
Wellcome Trust, and the UK Department of Health and Social Care using aid funding managed by the Fleming Fund.
View article: Nosocomial Outbreak of Ralstonia pickettii Infections Likely Linked to Saline Solutions in Germany from August 2023 to March 2024—Challenges in Medical Product-Related Outbreaks
Nosocomial Outbreak of Ralstonia pickettii Infections Likely Linked to Saline Solutions in Germany from August 2023 to March 2024—Challenges in Medical Product-Related Outbreaks Open
In December 2023, the World Health Organization reported an Australian nosocomial Ralstonia pickettii outbreak caused by contaminated saline solutions, causing bloodstream infections. The Antibiotic Resistance Surveillance, a Germany-wide …
View article: Global policy responses to antimicrobial resistance, 2021–22: a systematic governance analysis of 161 countries and territories
Global policy responses to antimicrobial resistance, 2021–22: a systematic governance analysis of 161 countries and territories Open
The global response to antimicrobial resistance was greatly affected by the income level of the nation, highlighting global disparities in antimicrobial resistance governance capacity. Lower scores in lower-income regions likely reflect sy…
View article: Self-reported acceptability and feasibility of a multimodal intervention to reduce antibiotic prescriptions for urinary tract infections in primary care: a process evaluation of the RedAres trial among general practitioners and medical practice assistants
Self-reported acceptability and feasibility of a multimodal intervention to reduce antibiotic prescriptions for urinary tract infections in primary care: a process evaluation of the RedAres trial among general practitioners and medical practice assistants Open
Background Urinary tract infections are common and lead to frequent and inappropriate antibiotic prescribing in primary care. The RedAres randomized controlled trial has shown to reduce second-line antibiotic use for urinary tract infectio…
View article: Role of vaccines in competitive displacement between SARS-CoV-2 viruses as revealed by the modeling of surveillance data
Role of vaccines in competitive displacement between SARS-CoV-2 viruses as revealed by the modeling of surveillance data Open
View article: Antimicrobial resistance burden landscape in Germany in 2019: a comparative country-level estimation
Antimicrobial resistance burden landscape in Germany in 2019: a comparative country-level estimation Open
Objectives Our aim was to present the most comprehensive set of pre-COVID-19 antimicrobial resistance (AMR) burden estimates for Germany to date, with a focus on regional variations and hotspots. Methods The study estimated deaths and disa…
View article: Letter to the editor: Use of integrated genomic surveillance by local public health authorities: recommendations based on a mixed-methods study of current adoption, applications and success factors, Germany, 2023.
Letter to the editor: Use of integrated genomic surveillance by local public health authorities: recommendations based on a mixed-methods study of current adoption, applications and success factors, Germany, 2023. Open
View article: Kinetic Patterns of Antibiotic Consumption in German Acute Care Hospitals from 2017 to 2023
Kinetic Patterns of Antibiotic Consumption in German Acute Care Hospitals from 2017 to 2023 Open
Background: Antimicrobial consumption (AMC) patterns, besides prescribing behaviors, reflect the changing epidemiology of infectious diseases. Routine surveillance data have been used to investigate the development of AMC from 2017 to 2023…
View article: Changing dynamics of bloodstream infections due to methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium in Germany, 2017–2023: a continued burden of disease approach
Changing dynamics of bloodstream infections due to methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium in Germany, 2017–2023: a continued burden of disease approach Open
View article: Changes in incidence and epidemiology of antimicrobial resistant pathogens before and during the COVID-19 pandemic in Germany, 2015–2022
Changes in incidence and epidemiology of antimicrobial resistant pathogens before and during the COVID-19 pandemic in Germany, 2015–2022 Open
Background Carbapenem-resistant Gram-negative bacteria and methicillin-resistant Staphylococcus aureus (MRSA) are among WHO’s priority pathogens with antimicrobial resistance (AMR). Studies suggest potential impacts of the COVID-19-pandemi…
View article: Quality indicators of long-term care for older people in OECD countries; a rapid scoping review
Quality indicators of long-term care for older people in OECD countries; a rapid scoping review Open
Background The COVID-19 pandemic has exposed the vulnerability of older people living in long-term care facilities (LTCF), highlighting the urgent need for research on the quality of care for this group of the population. There is no unive…
View article: Endocarditis associated with contamination of cardiovascular bioprostheses with Mycobacterium chelonae: a collaborative microbiological study
Endocarditis associated with contamination of cardiovascular bioprostheses with Mycobacterium chelonae: a collaborative microbiological study Open
German Federal Ministry of Education and Research.
View article: Burden and epidemiology of Campylobacter species in acute enteritis cases in Burkina Faso
Burden and epidemiology of Campylobacter species in acute enteritis cases in Burkina Faso Open
This study reveals a significant prevalence of Campylobacter species among patients with acute gastroenteritis, with a particularly high incidence observed in children under 5 years of age. Based on these findings, the implementation of ro…
View article: Genetic diversity of enteric viruses responsible of gastroenteritis in urban and rural Burkina Faso
Genetic diversity of enteric viruses responsible of gastroenteritis in urban and rural Burkina Faso Open
Background Viral gastrointestinal infections remain a major public health concern in developing countries. In Burkina Faso, there are very limited updated data on the circulating viruses and their genetic diversity. Objectives This study i…
View article: Automatisierte Surveillance und Risikovorhersage mit dem Ziel einer risikostratifizierten Infektionskontrolle und -prävention (RISK Prediction for Risk-stratified Infection Control and Prevention)
Automatisierte Surveillance und Risikovorhersage mit dem Ziel einer risikostratifizierten Infektionskontrolle und -prävention (RISK Prediction for Risk-stratified Infection Control and Prevention) Open
View article: The burden and treatment of non-communicable diseases among healthcare workers in sub-Saharan Africa: a multi-country cross-sectional study
The burden and treatment of non-communicable diseases among healthcare workers in sub-Saharan Africa: a multi-country cross-sectional study Open
Introduction Non-communicable diseases (NCDs), the leading cause of death globally, are estimated to overtake communicable diseases in sub-Sahara Africa, where healthcare workers (HCWs) play a crucial role in prevention and treatment, but …
View article: The gut microbiome, resistome, and mycobiome in preterm newborn infants and mouse pups: lack of lasting effects by antimicrobial therapy or probiotic prophylaxis
The gut microbiome, resistome, and mycobiome in preterm newborn infants and mouse pups: lack of lasting effects by antimicrobial therapy or probiotic prophylaxis Open
View article: Follow-up SARS-CoV-2 serological study of a health care worker cohort following COVID-19 booster vaccination
Follow-up SARS-CoV-2 serological study of a health care worker cohort following COVID-19 booster vaccination Open
View article: The percentage of antibiotic resistance in uncomplicated community-acquired urinary tract infections—findings of the RedAres project
The percentage of antibiotic resistance in uncomplicated community-acquired urinary tract infections—findings of the RedAres project Open
For single episodes of uUTI, all of theantibiotics studied can be recommended, at least asfar as their resistance profiles are concerned. Forrecurrent UTI, all but trimethoprim and cotrimoxazolecan be recommended. The second-choice antibio…
View article: Reported antibiotic use among patients in the multicenter ANDEMIA infectious diseases surveillance study in sub-saharan Africa
Reported antibiotic use among patients in the multicenter ANDEMIA infectious diseases surveillance study in sub-saharan Africa Open
Background Exposure to antibiotics has been shown to be one of the drivers of antimicrobial resistance (AMR) and is critical to address when planning and implementing strategies for combatting AMR. However, data on antibiotic use in sub-Sa…
View article: Implementation of the WHO core components of an infection prevention and control programme in two sub-saharan African acute health-care facilities: a mixed methods study
Implementation of the WHO core components of an infection prevention and control programme in two sub-saharan African acute health-care facilities: a mixed methods study Open
View article: Seroprevalence of anti-SARS-CoV-2 antibodies and risk of viral exposure among healthcare workers in the South Kivu province, eastern Democratic Republic of the Congo: a cross-sectional study
Seroprevalence of anti-SARS-CoV-2 antibodies and risk of viral exposure among healthcare workers in the South Kivu province, eastern Democratic Republic of the Congo: a cross-sectional study Open
Objectives Healthcare workers (HCWs) are on the frontline of combating COVID-19, hence are at elevated risk of contracting an infection with SARS-CoV-2. The present study aims to measure the impact of SARS-CoV-2 on HCWs in central sub-Saha…
View article: Proposed new definition for hospital-acquired SARS-CoV-2 infections: results of a confirmatory factor analysis
Proposed new definition for hospital-acquired SARS-CoV-2 infections: results of a confirmatory factor analysis Open
Objective: The present study aims to develop and discuss an extension of hospital-acquired severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections (HA-SIs) definition which goes beyond the use of time parameters alone. Desi…
View article: Prolonged carriage of OXA-244-carbapenemase-producing Escherichia coli complicates epidemiological investigations
Prolonged carriage of OXA-244-carbapenemase-producing Escherichia coli complicates epidemiological investigations Open
The rapid increase of OXA-244-producing Escherichia coli, predominantly driven by genetically clustered isolates of sequence type (ST)38, has been observed in at least nine European countries, including Germany. However, the reasons for th…
View article: GPs’ Perspective on a Multimodal Intervention to Enhance Guideline-Adherence in Uncomplicated Urinary Tract Infections: A Qualitative Process Evaluation of the Multicentric RedAres Cluster-Randomised Controlled Trial
GPs’ Perspective on a Multimodal Intervention to Enhance Guideline-Adherence in Uncomplicated Urinary Tract Infections: A Qualitative Process Evaluation of the Multicentric RedAres Cluster-Randomised Controlled Trial Open
Urinary tract infections (UTIs) are among the most common reasons patients seeking health care and antibiotics to be prescribed in primary care. However, general practitioners’ (GPs) guideline adherence is low. The RedAres randomised contr…
View article: Effects of a multimodal intervention in primary care to reduce second line antibiotic prescriptions for urinary tract infections in women: parallel, cluster randomised, controlled trial
Effects of a multimodal intervention in primary care to reduce second line antibiotic prescriptions for urinary tract infections in women: parallel, cluster randomised, controlled trial Open
Objectives To evaluate whether a multimodal intervention in general practice reduces the proportion of second line antibiotic prescriptions and the overall proportion of antibiotic prescriptions for uncomplicated urinary tract infections i…
View article: Association between hospital onset of infection and outcomes in sepsis patients – A propensity score matched cohort study based on health claims data in Germany
Association between hospital onset of infection and outcomes in sepsis patients – A propensity score matched cohort study based on health claims data in Germany Open
HAI sepsis patients face an increased risk of adverse outcomes both during the acute sepsis episode and in the long-term. Measures to prevent HAI and its progression into sepsis may be an opportunity to mitigate the burden of long-term imp…
View article: Scientific advisory councils in the COVID-19 response
Scientific advisory councils in the COVID-19 response Open
View article: Implementation of the WHO Core Components of an Infection Prevention and Control Programme in two Sub-Saharan African Acute Health-Care Facilities: a Mixed Methods Study
Implementation of the WHO Core Components of an Infection Prevention and Control Programme in two Sub-Saharan African Acute Health-Care Facilities: a Mixed Methods Study Open
BackgroundThe coronavirus pandemic again highlighted the need for robust health care facility infection prevention and control (IPC) programmes. WHO guidelines on the core components (CCs) of IPC programmes provides guidance for facilities…