Tim Kobelt
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View article: Identification of anaerobic bacterial strains by pyrolysis-gas chromatography-ion mobility spectrometry
Identification of anaerobic bacterial strains by pyrolysis-gas chromatography-ion mobility spectrometry Open
The rapid identification of bacterial pathogens is critical for the early diagnosis of severe clinical conditions, such as sepsis or implant-associated infections, and for the initiation of timely, targeted therapies. This need is particul…
View article: Ion mobility spectrometer with heated sample inlet - Solution to the issue of temperature effect on resolving power
Ion mobility spectrometer with heated sample inlet - Solution to the issue of temperature effect on resolving power Open
The approach and findings revealed in this work allow the construction of IMS with a heated sample inlet to prevent condensation of less volatile compounds while also maintaining the high resolving power of a drift tube at room temperature…
View article: A dual-polarity ion mobility spectrometer for capturing hyper-fast chromatographic peaks
A dual-polarity ion mobility spectrometer for capturing hyper-fast chromatographic peaks Open
For higher analytical performance, ion mobility spectrometers (IMS), especially when analyzing complex mixtures, are often coupled with gas chromatographs (GC). However, analysis time remains a critical parameter in gas chromatography. The…
View article: An open source isolated data acquisition with trigger pulse generation for ion mobility spectrometry
An open source isolated data acquisition with trigger pulse generation for ion mobility spectrometry Open
Ion mobility spectrometers (IMS) are used in a wide variety of applications, including trace gas detection in safety and security applications, but also in more analytical applications, e.g., in medicine or food quality monitoring. Consequ…
View article: Reliable Detection of Chemical Warfare Agents Using High Kinetic Energy Ion Mobility Spectrometry
Reliable Detection of Chemical Warfare Agents Using High Kinetic Energy Ion Mobility Spectrometry Open
High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) ionize and separate ions at reduced pressures of 10-40 mbar and over a wide range of reduced electric field strengths E/N of up to 120 Td. Their reduced operating pres…
View article: Ultra-fast polarity switching GC-IMS for the analysis of volatiles in biogas
Ultra-fast polarity switching GC-IMS for the analysis of volatiles in biogas Open
The Renewable Energy Act 2023 (§39i) requires reducing corn silage in biogas plants from 40 % to 30 % in 2026. Since corn silage yields the highest biogas per weight unit of all biogas feedstocks, this poses new challenges for biogas plant…
View article: Ultra-Fast Ion Mobility Spectrometer for High-Throughput Chromatography
Ultra-Fast Ion Mobility Spectrometer for High-Throughput Chromatography Open
Fast chromatography systems especially developed for high sample throughput applications require sensitive detectors with a high repetition rate. These high throughput techniques, including various chip-based microfluidic designs, often be…
View article: How to Improve the Resolving Power of Compact Electrospray Ionization Ion Mobility Spectrometers
How to Improve the Resolving Power of Compact Electrospray Ionization Ion Mobility Spectrometers Open
Every drift tube ion mobility spectrometer (IMS) has an optimum drift voltage to reach maximum resolving power. This optimum depends, among other things, on the temporal and spatial width of the injected ion packet and the pressure within …
View article: A Simple Analytical Model for Predicting the Detectable Ion Current in Ion Mobility Spectrometry Using Corona Discharge Ionization Sources
A Simple Analytical Model for Predicting the Detectable Ion Current in Ion Mobility Spectrometry Using Corona Discharge Ionization Sources Open
Corona discharge ionization sources are often used in ion mobility spectrometers (IMS) when a non-radioactive ion source with high ion currents is required. Typically, the corona discharge is followed by a reaction region where analyte ion…
View article: Design and evaluation of split-ring resonators for aptamer-based biosensors
Design and evaluation of split-ring resonators for aptamer-based biosensors Open
Split-ring resonators are electrical circuits, which enable highly sensitive readout of split capacity changes via a measurement of the shift in the resonance frequency. Thus, functionalization of the split allows the development of biosen…
View article: A3.4 - Biosensor based on a split-ring resonator
A3.4 - Biosensor based on a split-ring resonator Open
Split-ring resonators are electrical circuits, which enable highly sensitive readout of split capacity changes via a measurement of shift of the resonance frequency.Thus, functionalization of the split allows the development of biosensors,…