Timothy A Liddle
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View article: Breeding males, but not females, have elevated androgen receptor expression in the northern house wren (<i>Troglodytes aedon</i>), a temperate songbird with female song
Breeding males, but not females, have elevated androgen receptor expression in the northern house wren (<i>Troglodytes aedon</i>), a temperate songbird with female song Open
In many male temperate-breeding songbirds, increased plasma testosterone in the early breeding season regenerates song control nuclei that regulate song. Females of some temperate species also sing but have lower circulating testosterone c…
View article: Seasonal neurogenomic changes provide genetic links between male song and testosterone-mediated neurogenesis in a wild songbird
Seasonal neurogenomic changes provide genetic links between male song and testosterone-mediated neurogenesis in a wild songbird Open
Seasonal changes in testosterone mediate the transition from reduced singing in the non-breeding season to high song rates in the early breeding season in male temperate songbirds, a process accompanied by marked neurogenesis in song contr…
View article: Hypothalamic deiodinase type-3 establishes the period of circannual interval timing in mammals
Hypothalamic deiodinase type-3 establishes the period of circannual interval timing in mammals Open
Animals respond to environmental cues to time phenological events, but the intrinsic mechanism of circannual timing remains elusive. We used transcriptomic sequencing and frequent sampling, during three distinct phases (induction, maintena…
View article: Hypothalamic deiodinase type-3 establishes the period of circannual interval timing in mammals
Hypothalamic deiodinase type-3 establishes the period of circannual interval timing in mammals Open
Animals respond to environmental cues to time phenological events, but the intrinsic mechanism of circannual timing remains elusive. We used transcriptomic sequencing and frequent sampling of multiple hypothalamic nuclei in Djungarian hams…
View article: Prolactin Regulates Seasonal Changes in Renal Rheostasis in Djungarian Hamsters
Prolactin Regulates Seasonal Changes in Renal Rheostasis in Djungarian Hamsters Open
Seasonal changes in a photoperiod regulate multiple physiological systems in vertebrates, including metabolism, reproduction, and immune function. Kidney mass and renal physiology are known to vary annually, but the endocrine and molecular…
View article: Hypotheses in light detection by vertebrate ancient opsin in the bird brain
Hypotheses in light detection by vertebrate ancient opsin in the bird brain Open
Extra‐retinal photoreception is common across fish and avian species. In birds, the hypothalamus contains non‐visual photoreceptors that detect light and regulate multiple endocrine systems. To date, light‐dependent control of seasonal rep…
View article: Dissociating Mechanisms That Underlie Seasonal and Developmental Programs for the Neuroendocrine Control of Physiology in Birds
Dissociating Mechanisms That Underlie Seasonal and Developmental Programs for the Neuroendocrine Control of Physiology in Birds Open
Long-term programmed rheostatic changes in physiology are essential for animal fitness. Hypothalamic nuclei and the pituitary gland govern key developmental and seasonal transitions in reproduction. The aim of this study was to identify th…
View article: Prolactin Mediates Long-Term, Seasonal Rheostatic Regulation of Body Mass in Female Mammals
Prolactin Mediates Long-Term, Seasonal Rheostatic Regulation of Body Mass in Female Mammals Open
A series of well-described anabolic and catabolic neuropeptides are known to provide short-term, homeostatic control of energy balance. The mechanisms that govern long-term, rheostatic control of regulated changes in energy balance are les…
View article: FSHβ links photoperiodic signaling to seasonal reproduction in Japanese quail
FSHβ links photoperiodic signaling to seasonal reproduction in Japanese quail Open
Annual cycles in daylength provide an initial predictive environmental cue that plants and animals use to time seasonal biology. Seasonal changes in photoperiodic information acts to entrain endogenous programs in physiology to optimize an…
View article: FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail
FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail Open
Annual cycles in daylength provide an initial predictive environmental cue that plants and animals use to time seasonal biology. Seasonal changes in photoperiodic information acts to entrain endogenous programs in physiology to optimize an…
View article: Reviewer #2 (Public Review): FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail
Reviewer #2 (Public Review): FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail Open
Annual cycles in daylength provide an initial predictive environmental cue that plants and animals use to time seasonal biology. Seasonal changes in photoperiodic information acts to entrain endogenous programs in physiology to optimize an…
View article: Author Response: FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail
Author Response: FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail Open
Annual cycles in daylength provide an initial predictive environmental cue that plants and animals use to time seasonal biology. Seasonal changes in photoperiodic information acts to entrain endogenous programs in physiology to optimize an…
View article: Reviewer #1 (Public Review): FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail
Reviewer #1 (Public Review): FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail Open
Annual cycles in daylength provide an initial predictive environmental cue that plants and animals use to time seasonal biology. Seasonal changes in photoperiodic information acts to entrain endogenous programs in physiology to optimize an…
View article: FSHβ links photoperiodic signaling to seasonal reproduction in Japanese quail
FSHβ links photoperiodic signaling to seasonal reproduction in Japanese quail Open
Annual cycles in daylength provide an initial predictive environmental cue that plants and animals use to time seasonal biology. Seasonal changes in photoperiodic information acts to entrain endogenous programs in physiology to optimize an…
View article: FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail
FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail Open
Endogenous programs in avian reproductive seasonal life history transitions have been known for over 30 years. Attempts to identify the neural and molecular substrates of photoperiodic time measurement have, to date, focussed on blunt chan…
View article: <i>FSH</i> β links photoperiodic signalling to seasonal reproduction in Japanese quail
<i>FSH</i> β links photoperiodic signalling to seasonal reproduction in Japanese quail Open
Annual cycles in daylength provide an initial predictive environmental cue that plants and animals use to time seasonal biology. Seasonal changes in photoperiodic information acts to entrain endogenous programs in physiology to optimize an…
View article: Abundance, efficiency, and stability of reference transcript expression in a seasonal rodent: The Siberian hamster
Abundance, efficiency, and stability of reference transcript expression in a seasonal rodent: The Siberian hamster Open
Quantitative PCR (qPCR) is a common molecular tool to analyse the expression of transcripts in non-traditional animal models. Most animals experience tissue-specific seasonal changes in cell structure, growth, and cellular function. As a c…