Timothy Choi
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View article: Bilateral Pedicle Screw Fixation Vs Unilateral Pedicle Screw Fixation for Single Level Lateral Lumbar Interbody Fusion: Outcomes, Cost Analysis, and Radiation Exposure
Bilateral Pedicle Screw Fixation Vs Unilateral Pedicle Screw Fixation for Single Level Lateral Lumbar Interbody Fusion: Outcomes, Cost Analysis, and Radiation Exposure Open
View article: Impact of multidisciplinary care of diabetic foot infections for inpatients at Campbelltown Hospital
Impact of multidisciplinary care of diabetic foot infections for inpatients at Campbelltown Hospital Open
View article: Impact of Multidisciplinary Care of Diabetic Foot Infections for Inpatients at Campbelltown Hospital
Impact of Multidisciplinary Care of Diabetic Foot Infections for Inpatients at Campbelltown Hospital Open
Background: Diabetic foot infection (DFI), including diabetic foot ulcer, is a serious complication of diabetes, particularly in the South Western Sydney (SWS) region where it is a leading cause of diabetes-related hospitalisations. Multid…
View article: P740: IMPACT OF MAGROLIMAB IN COMBINATION WITH AZACITIDINE ON RED BLOOD CELLS IN PATIENTS WITH HIGHER-RISK MYELODYSPLASTIC SYNDROME (HR MDS)
P740: IMPACT OF MAGROLIMAB IN COMBINATION WITH AZACITIDINE ON RED BLOOD CELLS IN PATIENTS WITH HIGHER-RISK MYELODYSPLASTIC SYNDROME (HR MDS) Open
Background: Magrolimab is a monoclonal antibody that blocks CD47, a “don’t eat me” signal expressed on cancer cells, to escape immune surveillance and macrophage-mediated clearance. Prior preclinical studies have shown that CD47 is critica…
View article: Targeting macrophage checkpoint inhibitor SIRPα for anticancer therapy
Targeting macrophage checkpoint inhibitor SIRPα for anticancer therapy Open
The CD47/signal regulatory protein α (Cd47/SIRPα)interaction provides a macrophage immune checkpoint pathway that plays a critical role in cancer immune evasion across multiple cancers. Here, we report the engineering of a humanized anti-S…
View article: Programmed cell removal by calreticulin in tissue homeostasis and cancer
Programmed cell removal by calreticulin in tissue homeostasis and cancer Open
Macrophage-mediated programmed cell removal (PrCR) is a process essential for the clearance of unwanted (damaged, dysfunctional, aged, or harmful) cells. The detection and recognition of appropriate target cells by macrophages is a critica…