Timothy G. Bromage
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View article: Correction to: Characteristics of lithic artifact weathering at the Semizbugu surface site complex in semi-arid Central Kazakhstan
Correction to: Characteristics of lithic artifact weathering at the Semizbugu surface site complex in semi-arid Central Kazakhstan Open
View article: <b>Canagliflozin-induced adaptive metabolism in bone</b>
<b>Canagliflozin-induced adaptive metabolism in bone</b> Open
Sodium-glucose transporter-2 inhibitor (SGLT2i) drugs are widely used for lowering blood glucose levels independent of insulin. Beyond this, these drugs induce various metabolic changes, including weight loss and impaired bone integrity. T…
View article: Characteristics of lithic artifact weathering at the Semizbugu surface site complex in semi-arid Central Kazakhstan
Characteristics of lithic artifact weathering at the Semizbugu surface site complex in semi-arid Central Kazakhstan Open
View article: An ultrastructure analysis of the developing human anterior cruciate ligament tibial enthesis
An ultrastructure analysis of the developing human anterior cruciate ligament tibial enthesis Open
This study aimed to investigate the ultrastructural anatomy of the developing ACL tibial enthesis. We hypothesized that enthesis architecture would progressively mature and remodel, eventually resembling that of the adult by the early post…
View article: Correction: The Swine Plasma Metabolome Chronicles "Many Days" Biological Timing and Functions Linked to Growth
Correction: The Swine Plasma Metabolome Chronicles "Many Days" Biological Timing and Functions Linked to Growth Open
[This corrects the article DOI: 10.1371/journal.pone.0145919.].
View article: Correction: ‘Dental cementum virtual histology of Neanderthal teeth from Krapina (Croatia, 130–120 kyr): an informed estimate of age, sex and adult stressors’ (2022), by Cerrito <i>et al.</i>
Correction: ‘Dental cementum virtual histology of Neanderthal teeth from Krapina (Croatia, 130–120 kyr): an informed estimate of age, sex and adult stressors’ (2022), by Cerrito <i>et al.</i> Open
View article: Humans and a subterranean rodent have contrasting biological rhythms
Humans and a subterranean rodent have contrasting biological rhythms Open
Here we show that naked mole rats (NMR’s) have an extraordinary survival advantage. We base this statement on a spectral analysis of the time series of measured intervals in teeth of 3 species (NMR’s, Killer Whale, and Modern Humans). We u…
View article: Long-term effects of canagliflozin treatment on the skeleton of aged UM-HET3 mice
Long-term effects of canagliflozin treatment on the skeleton of aged UM-HET3 mice Open
View article: Effects of LED curing light on silver diamine fluoride penetration into dentin
Effects of LED curing light on silver diamine fluoride penetration into dentin Open
This ex-vivo study investigated the effect of a light-emitting diode (LED) curing light on the depth of penetration of Silver Diamine Fluoride (SDF) into carious lesions. Twenty-four primary teeth with untreated caries lesions were allocat…
View article: Life history in primate teeth is revealed by changes in major and minor element concentrations measured via field-emission SEM-EDS analysis
Life history in primate teeth is revealed by changes in major and minor element concentrations measured via field-emission SEM-EDS analysis Open
Overcoming the non-specificity of histological accentuated growth lines in hard tissues is an ongoing challenge. Identifying season at death and reproductive events has profound implications for evolutionary, ecological and conservation st…
View article: Elemental composition of primary lamellar bone differs between parous and nulliparous rhesus macaque females
Elemental composition of primary lamellar bone differs between parous and nulliparous rhesus macaque females Open
Extracting life history information from mineralized hard tissues of extant and extinct species is an ongoing challenge in evolutionary and conservation studies. Primary lamellar bone is a mineralized tissue with multidien periodicity that…
View article: Dental cementum virtual histology of Neanderthal teeth from Krapina (Croatia, 130–120 kyr): an informed estimate of age, sex and adult stressors
Dental cementum virtual histology of Neanderthal teeth from Krapina (Croatia, 130–120 kyr): an informed estimate of age, sex and adult stressors Open
The evolution of modern human reproductive scheduling is an aspect of our life history that remains vastly uncomprehended. The present work aims to address this gap by validating a non-destructive cutting-edge methodology to infer adult li…
View article: Microbial Contamination Survey of Environmental Fresh and Saltwater Resources of Upolu Island, Samoa
Microbial Contamination Survey of Environmental Fresh and Saltwater Resources of Upolu Island, Samoa Open
Analysis of microbe diversity in freshwater resources and nearshore seawater samples of Upolu Island was performed to investigate the distribution of harmful bacteria. For this, 124 samples were collected from 23 river systems, two volcani…
View article: The oronasopharyngeal space and renewed formalization of the functional matrix hypothesis
The oronasopharyngeal space and renewed formalization of the functional matrix hypothesis Open
Conceptualization of the functional matrix hypothesis (FMH) by Melvin L. Moss [1,2] remains a pillar of orthodontic theory to explain compensatory growth of the craniofacial skeletal complex. Funct...
View article: The Cutting Edge: Surface Texture Analysis following Resection of Nerve Stumps Using Various Instruments
The Cutting Edge: Surface Texture Analysis following Resection of Nerve Stumps Using Various Instruments Open
Background: Preparation of nerve ends is an essential part of nerve repair surgery. Multiple instruments have been described for this purpose; however, no consensus exists regarding which is the least traumatic for tissue handling. We beli…
View article: Adjuvant therapy with 1% alendronate gel for experimental periodontitis treatment in rats
Adjuvant therapy with 1% alendronate gel for experimental periodontitis treatment in rats Open
Locally delivered 1% ALN gel used as an adjunct to SRP enhanced bone regeneration in the furcation region in a rat model of experimental periodontitis.
View article: Biominerals Fossilisation: Fish Bone Diagenesis in Plio–Pleistocene African Hominid Sites of Malawi
Biominerals Fossilisation: Fish Bone Diagenesis in Plio–Pleistocene African Hominid Sites of Malawi Open
Fish fossilisation is relatively poorly known, and skeletal element modifications resulting from predation, burial and diagenesis need to be better investigated. In this article, we aim to provide new results about surface, structural and …
View article: MH-ICP-MS Analysis of the Freshwater and Saltwater Environmental Resources of Upolu Island, Samoa
MH-ICP-MS Analysis of the Freshwater and Saltwater Environmental Resources of Upolu Island, Samoa Open
The elemental composition of freshwater and saltwater samples around the South Pacific island of Upolu, Samoa has been investigated together with other indicators of water quality. Up to 69 elements from Li (3) to U (92) are measured in ea…
View article: A comprehensive survey of Retzius periodicities in fossil hominins and great apes
A comprehensive survey of Retzius periodicities in fossil hominins and great apes Open
View article: Parturitions, menopause and other physiological stressors are recorded in dental cementum microstructure
Parturitions, menopause and other physiological stressors are recorded in dental cementum microstructure Open
View article: Short and long period growth markers of enamel formation distinguish European Pleistocene hominins
Short and long period growth markers of enamel formation distinguish European Pleistocene hominins Open
Characterizing dental development in fossil hominins is important for distinguishing between them and for establishing where and when the slow overall growth and development of modern humans appeared. Dental development of australopiths an…
View article: Hybrid Bone Scaffold Induces Bone Bridging in Goat Calvarial Critical Size Defects Without Growth Factor Augmentation
Hybrid Bone Scaffold Induces Bone Bridging in Goat Calvarial Critical Size Defects Without Growth Factor Augmentation Open
In the present study, a series of four different scaffolds were comparatively evaluated in a goat calvarial critical size defect model. Such studies are only rarely reported in the literature. In our work, E1001(1k), a member of a large co…
View article: Faster growth corresponds with shallower linear hypoplastic defects in great ape canines
Faster growth corresponds with shallower linear hypoplastic defects in great ape canines Open
View article: Layered patterns in nature, medicine, and materials: quantifying anisotropic structures and cyclicity
Layered patterns in nature, medicine, and materials: quantifying anisotropic structures and cyclicity Open
Various natural patterns—such as terrestrial sand dune ripples, lamellae in vertebrate bones, growth increments in fish scales and corals, aortas and lamellar corpuscles in humans and animals—comprise layers of different thicknesses and le…
View article: Peer Review #2 of "Layered patterns in nature, medicine, and materials: quantifying anisotropic structures and cyclicity (v0.1)"
Peer Review #2 of "Layered patterns in nature, medicine, and materials: quantifying anisotropic structures and cyclicity (v0.1)" Open
Various natural patterns-such as terrestrial sand dune ripples, lamellae in vertebrate bones, growth increments in fish scales and corals, aortas and lamellar corpuscles in humans and animals-comprise layers of different thicknesses and le…
View article: Peer Review #1 of "Layered patterns in nature, medicine, and materials: quantifying anisotropic structures and cyclicity (v0.1)"
Peer Review #1 of "Layered patterns in nature, medicine, and materials: quantifying anisotropic structures and cyclicity (v0.1)" Open
Various natural patterns-such as terrestrial sand dune ripples, lamellae in vertebrate bones, growth increments in fish scales and corals, aortas and lamellar corpuscles in humans and animals-comprise layers of different thicknesses and le…
View article: Peer Review #1 of "Layered patterns in nature, medicine, and materials: quantifying anisotropic structures and cyclicity (v0.2)"
Peer Review #1 of "Layered patterns in nature, medicine, and materials: quantifying anisotropic structures and cyclicity (v0.2)" Open
Various natural patterns-such as terrestrial sand dune ripples, lamellae in vertebrate bones, growth increments in fish scales and corals, aortas and lamellar corpuscles in humans and animals-comprise layers of different thicknesses and le…
View article: Parenchymal and stromal tissue regeneration of tooth organ by pivotal signals reinstated in decellularized matrix
Parenchymal and stromal tissue regeneration of tooth organ by pivotal signals reinstated in decellularized matrix Open
View article: Differential regulation of Ca <sup>2+</sup> influx by ORAI channels mediates enamel mineralization
Differential regulation of Ca <sup>2+</sup> influx by ORAI channels mediates enamel mineralization Open
SOCE mediated by ORAI1 affects the metabolism, redox status, and function of enamel cells in teeth.
View article: The evolutionary history of the human face
The evolutionary history of the human face Open