Jarrad Hampton‐Marcell
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View article: Dietary Protein Source Shapes Gut Microbial Structure and Predicted Functional Potential: A Systematic Integrative Re-analysis Using Machine Learning
Dietary Protein Source Shapes Gut Microbial Structure and Predicted Functional Potential: A Systematic Integrative Re-analysis Using Machine Learning Open
This study presents the first standardized systematic integrative re-analysis of murine protein-intervention microbiome datasets, integrating taxonomic, machine learning, and predicted functional profiling to identify robust microbial and …
View article: Effect of Acute Gut Butyrate Delivery on Blood Pressure in Black Individuals With Hypertension: A Proof-of-Concept Randomized Controlled Study.
Effect of Acute Gut Butyrate Delivery on Blood Pressure in Black Individuals With Hypertension: A Proof-of-Concept Randomized Controlled Study. Open
BACKGROUND: Hypertension is a global health crisis linked to increased heart disease and stroke. Black individuals have the greatest burden of hypertension and related diseases. Recent research suggests that the gut microbial production of…
View article: Effect of Acute Gut Butyrate Delivery on Blood Pressure in Black Individuals With Hypertension: A Proof‐of‐Concept Randomized Controlled Study
Effect of Acute Gut Butyrate Delivery on Blood Pressure in Black Individuals With Hypertension: A Proof‐of‐Concept Randomized Controlled Study Open
Background Hypertension is a global health crisis linked to increased heart disease and stroke. Black individuals have the greatest burden of hypertension and related diseases. Recent research suggests that the gut microbial production of …
View article: The athlete microbiome project: Integrating deep learning to reveal microbial associations of physical fitness
The athlete microbiome project: Integrating deep learning to reveal microbial associations of physical fitness Open
Regular exercise improves human fitness and health through direct effects on muscle and metabolism and indirect effects involving the gut microbiome. To better understand the relationship between the gut microbiome and physical fitness, we…
View article: Going green: Recycling transcriptomes to infer evolutionary relationships, gene duplication, gene tree conflict, and patterns of molecular evolution in the Apocynaceae
Going green: Recycling transcriptomes to infer evolutionary relationships, gene duplication, gene tree conflict, and patterns of molecular evolution in the Apocynaceae Open
Background and Aims The flowering plant family Apocynaceae exhibits diverse adaptations with biological and pharmaceutical significance, many of which have been studied with RNA-seq. However, despite the available transcriptomic data, no f…
View article: Gut Butyrate Reduction in Blood Pressure Is Associated with Other Vegetables, Whole Fruit, Total Grains, and Sodium Intake
Gut Butyrate Reduction in Blood Pressure Is Associated with Other Vegetables, Whole Fruit, Total Grains, and Sodium Intake Open
Background: African Americans (AA) are disproportionally affected by hypertension (HTN). Gut microbiome metabolites (e.g., butyrate) may mediate the relationship between the microbiome and blood pressure (BP). Previous research reports a c…
View article: Dietary Protein Source Shapes Gut Microbial Structure and Predicted Function: A Meta-Analysis with Machine Learning
Dietary Protein Source Shapes Gut Microbial Structure and Predicted Function: A Meta-Analysis with Machine Learning Open
Background Dietary proteins shape gut microbial ecology, yet the taxonomic and functional consequences of plant- versus animal-based proteins remain poorly defined. Although digestibility and fermentation profiles differ by protein type, a…
View article: Gut Butyrate Reduction in Blood Pressure Is Associated with Other Vegetables, Whole Fruit, Total Grains, and Sodium Intake
Gut Butyrate Reduction in Blood Pressure Is Associated with Other Vegetables, Whole Fruit, Total Grains, and Sodium Intake Open
Background: African Americans (AA) are disproportionally affected by hypertension (HTN). Gut microbiome metabolites (e.g., butyrate) may mediate the relationship between the microbiome and blood pressure (BP). Previous research reports a c…
View article: Utility of a quantitative approach to microbial dysbiosis using machine learning in an African American cohort with self-reported hair loss
Utility of a quantitative approach to microbial dysbiosis using machine learning in an African American cohort with self-reported hair loss Open
Microbial dysbiosis has been identified as a therapeutic target for several dermatologic conditions. However, the concept of dysbiosis is poorly defined, limiting reproducibility. We developed a reproducible metric for dysbiosis that can b…
View article: Semblans: automated assembly and processing of RNA-seq data
Semblans: automated assembly and processing of RNA-seq data Open
Motivation Recent advancements in parallel sequencing methods have precipitated a surge in publicly available short-read sequence data. This has encouraged the development of novel computational tools for the de novo assembly of transcript…
View article: Gut microbiota are differentially correlated with blood pressure status in African American collegiate athletes: A pilot study
Gut microbiota are differentially correlated with blood pressure status in African American collegiate athletes: A pilot study Open
Hypertension (HTN) is common among athletes and the most recent epidemiologic data reports that cardiovascular (CV) sudden death is significantly greater in African Americans (AAs). Gut microbial dysbiosis (a poorly diverse stool microbial…
View article: Machine Learning Reveals Microbial Taxa Associated with a Swim across the Pacific Ocean
Machine Learning Reveals Microbial Taxa Associated with a Swim across the Pacific Ocean Open
Purpose: This study aimed to characterize the association between microbial dynamics and excessive exercise. Methods: Swabbed fecal samples, body composition (percent body fat), and swimming logs were collected (n = 94) from a single indiv…
View article: Gut microbiota are differentially correlated with blood pressure status in African American collegiate athletes: A pilot study
Gut microbiota are differentially correlated with blood pressure status in African American collegiate athletes: A pilot study Open
Hypertension (HTN) is common among athletes and the most recent epidemiologic data reports that cardiovascular (CV) sudden death is significantly greater in African Americans (AAs). Gut microbial dysbiosis (a poorly diverse stool microbial…
View article: Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature
Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature Open
Malignant tumors, characterized by uncontrolled cell proliferation, are a leading global health challenge, responsible for over 9.7 million deaths in 2022, with new cases expected to rise to 35 million annually by 2050. Immunotherapy is pr…
View article: Gut check: Unveiling the influence of acute exercise on the gut microbiota
Gut check: Unveiling the influence of acute exercise on the gut microbiota Open
The human gastrointestinal microbiota and its unique metabolites regulate a diverse array of physiological processes with substantial implications for human health and performance. Chronic exercise training positively modulates the gut mic…
View article: Swimming and the human microbiome at the intersection of sports, clinical, and environmental sciences: A scoping review of the literature
Swimming and the human microbiome at the intersection of sports, clinical, and environmental sciences: A scoping review of the literature Open
The human microbiota is comprised of more than 10–100 trillion microbial taxa and symbiotic cells. Two major human sites that are host to microbial communities are the gut and the skin. Physical exercise has favorable effects on the struct…
View article: Children with Autism and Their Typically Developing Siblings Differ in Amplicon Sequence Variants and Predicted Functions of Stool-Associated Microbes
Children with Autism and Their Typically Developing Siblings Differ in Amplicon Sequence Variants and Predicted Functions of Stool-Associated Microbes Open
Autism spectrum disorder (ASD), which now affects 1 in 59 children in the United States, is known to have comorbidity with gut disorders of a variety of types; however, the link to the microbiome remains poorly characterized. Recent work h…
View article: Bacterial communities associated with cell phones and shoes
Bacterial communities associated with cell phones and shoes Open
Background Every human being carries with them a collection of microbes, a collection that is likely both unique to that person, but also dynamic as a result of significant flux with the surrounding environment. The interaction of the huma…
View article: Concurrent measurement of microbiome and allergens in the air of bedrooms of allergy disease patients in the Chicago area
Concurrent measurement of microbiome and allergens in the air of bedrooms of allergy disease patients in the Chicago area Open
The particulate and biological components of indoor air have a substantial impact on human health, especially immune respiratory conditions such as asthma. To better explore the relationship between allergens, the microbial community, and …
View article: Bacterial communities associated with cell phones and shoes
Bacterial communities associated with cell phones and shoes Open
Background: Every human being carries with them a collection of microbes, a collection that is likely both unique to that person, but also dynamic as a result of significant flux with the surrounding environment. The interaction of the hum…
View article: Bacterial communities associated with cell phones and shoes
Bacterial communities associated with cell phones and shoes Open
Background: Every human being carries with them a collection of microbes, a collection that is likely both unique to that person, but also dynamic as a result of significant flux with the surrounding environment. The interaction of the hum…
View article: Additional file 1: of Concurrent measurement of microbiome and allergens in the air of bedrooms of allergy disease patients in the Chicago area
Additional file 1: of Concurrent measurement of microbiome and allergens in the air of bedrooms of allergy disease patients in the Chicago area Open
Table S1. Community diversity based on selected abiotic variables. (CSV 343 b)
View article: Additional file 3: of Concurrent measurement of microbiome and allergens in the air of bedrooms of allergy disease patients in the Chicago area
Additional file 3: of Concurrent measurement of microbiome and allergens in the air of bedrooms of allergy disease patients in the Chicago area Open
Table S2. Differentially Abundance OTUs between households with and without dogs. (CSV 56 kb)
View article: Exploring Animation Styles to Communicate the Effects of Exercise on Gut Microbiota
Exploring Animation Styles to Communicate the Effects of Exercise on Gut Microbiota Open
This study of learning principle-designed scientific animation sought to determine whether animation is an effective teaching tool and what components of animation fulfill that role. It is known that there is a lack of animations that conc…
View article: Environmental Sources of Bacteria Differentially Influence Host-Associated Microbial Dynamics
Environmental Sources of Bacteria Differentially Influence Host-Associated Microbial Dynamics Open
These results provide valuable insights into the ecological influence of exogenous microbial exposure, as well as laying the foundation for improving aquarium management practices. By comparing data for dolphins from aquaria that use natur…
View article: American Gut: an Open Platform for Citizen Science Microbiome Research
American Gut: an Open Platform for Citizen Science Microbiome Research Open
We show that a citizen science, self-selected cohort shipping samples through the mail at room temperature recaptures many known microbiome results from clinically collected cohorts and reveals new ones. Of particular interest is integrati…