Timothy L. Tan
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View article: Effect of Antibiotic Spacer Dosing on Treatment Success in Two-Stage Exchange for Periprosthetic Joint Infection
Effect of Antibiotic Spacer Dosing on Treatment Success in Two-Stage Exchange for Periprosthetic Joint Infection Open
Introduction: In two-stage exchange for periprosthetic joint infection (PJI), adding antibiotics to cement spacers is the standard of care; however, little is known about optimal dosage. There is emphasis on using >3.6 g of total antibioti…
View article: Optimal reimplantation timing in two-stage exchange for periprosthetic joint infection: an observative cohort study in Asian population
Optimal reimplantation timing in two-stage exchange for periprosthetic joint infection: an observative cohort study in Asian population Open
Background The optimal timing for reimplantation for periprosthetic joint infection (PJI) has not been established and varies from a few weeks to several months. The aim of this study was to assess the commendable time between implant remo…
View article: Comparison of Static and Articulating Spacers After Periprosthetic Joint Infection
Comparison of Static and Articulating Spacers After Periprosthetic Joint Infection Open
Introduction: There is no consensus on whether articulating or static spacers are superior during two-stage exchange arthroplasty for periprosthetic joint infection. We aimed to compare surgical time, need for extensile exposure, surgical …
View article: Influence of the Type of Bone Cement Used in Two-Stage Exchange Arthroplasty for Chronic Periarticular Joint Infection on the Spacer Replacement and Reinfection Rate
Influence of the Type of Bone Cement Used in Two-Stage Exchange Arthroplasty for Chronic Periarticular Joint Infection on the Spacer Replacement and Reinfection Rate Open
Background: Antibiotic-loaded bone cement (ALBC) spacers are used in the first stage when treating periprosthetic joint infection (PJI). This study aimed to investigate whether a spacer made from commercial ALBC or plain bone cement with a…
View article: Post-operative prophylactic antibiotics in aseptic revision hip and knee arthroplasty: a propensity score matching analysis
Post-operative prophylactic antibiotics in aseptic revision hip and knee arthroplasty: a propensity score matching analysis Open
The use of extended antibiotic (EA) prophylaxis (> 24 h) remains controversial in aseptic revision arthroplasty. We sought to determine whether EA prophylaxis reduces the risk of periprosthetic joint infection (PJI) in aseptic revision hip…
View article: Tale of Two Alopecias: Alopecia Areata and Central Centrifugal Cicatricial Alopecia Occurring in the Same Patient
Tale of Two Alopecias: Alopecia Areata and Central Centrifugal Cicatricial Alopecia Occurring in the Same Patient Open
Introduction: Scarring and non-scarring alopecias have rarely been described to occur together in the same patient. Distinguishing these two different types of alopecia is important as treatment and prognosis can be different. Case present…
View article: CORR Insights®: What Are the Long-term Outcomes of Mortality, Quality of Life, and Hip Function after Prosthetic Joint Infection of the Hip? A 10-year Follow-up from Sweden
CORR Insights®: What Are the Long-term Outcomes of Mortality, Quality of Life, and Hip Function after Prosthetic Joint Infection of the Hip? A 10-year Follow-up from Sweden Open
Where Are We Now? Periprosthetic joint infection (PJI) remains one of the most common and devastating complications of total joint arthroplasty. PJI causes serious morbidity, revision surgery, and a high risk of death. The economic burden …
View article: CORR Insights®: What Is the Optimal Timing for Reading the Leukocyte Esterase Strip for the Diagnosis of Periprosthetic Joint Infection?
CORR Insights®: What Is the Optimal Timing for Reading the Leukocyte Esterase Strip for the Diagnosis of Periprosthetic Joint Infection? Open
Where Are We Now? Periprosthetic joint infection (PJI) is a devastating and costly complication following total joint arthroplasty. One of the challenges of diagnosing PJI is the lack of point-of-care tests currently available. The appeal …
View article: When Total Joint Arthroplasty After Septic Arthritis Can Be Safely Performed
When Total Joint Arthroplasty After Septic Arthritis Can Be Safely Performed Open
Background: Patients undergoing total joint arthroplasty (TJA) following septic arthritis are at higher risk for developing periprosthetic joint infection (PJI). Minimal literature is available to guide surgeons on the optimal timing of TJ…
View article: Association of Laminar Airflow During Primary Total Joint Arthroplasty With Periprosthetic Joint Infection
Association of Laminar Airflow During Primary Total Joint Arthroplasty With Periprosthetic Joint Infection Open
This study suggests that the use of LAF in the operating room was not associated with a reduced incidence of PJI after primary total joint arthroplasty. With an appropriate perioperative protocol for infection prevention, LAF does not seem…
View article: 2020 Frank Stinchfield Award: Identifying who will fail following irrigation and debridement for prosthetic joint infection
2020 Frank Stinchfield Award: Identifying who will fail following irrigation and debridement for prosthetic joint infection Open
Aims Failure of irrigation and debridement (I&D) for prosthetic joint infection (PJI) is influenced by numerous host, surgical, and pathogen-related factors. We aimed to develop and validate a practical, easy-to-use tool based on machine l…
View article: Dipyridamole-thallium scanning doesn't reduce 90-day cardiac complications and mortality in femoral neck fracture patients undergoing hemiarthroplasty: a propensity-score-matched analysis in an Asian population
Dipyridamole-thallium scanning doesn't reduce 90-day cardiac complications and mortality in femoral neck fracture patients undergoing hemiarthroplasty: a propensity-score-matched analysis in an Asian population Open
Background: This study aimed to evaluate the effect of dipyridamole-thallium scanning on 90-day cardiac complications and mortality in patients with femoral neck fracture treated with hemiarthroplasty.Methods: Between 2008 and 2015, 844 co…
View article: Does preoperative dipyridamole-thallium scanning reduce 90-day cardiac complications and mortality in patients with femoral neck fractures undergoing hemiarthroplasty?
Does preoperative dipyridamole-thallium scanning reduce 90-day cardiac complications and mortality in patients with femoral neck fractures undergoing hemiarthroplasty? Open
Background: This study aimed to evaluate the effect of dipyridamole-thallium scanning on 90-day cardiac complications and mortality in patients with femoral neck fracture treated with hemiarthroplasty. Methods : Between 2008 and 2015, 844 …
View article: Survivorship, Complications, and Outcomes Following Distal Femoral Replacement Using Megaprosthesis
Survivorship, Complications, and Outcomes Following Distal Femoral Replacement Using Megaprosthesis Open
Introduction: Distal femoral bone loss is often managed with a combination of modular prostheses, structural and non-structural allografts, and metal augmentation. However, when bone loss of the distal femur is severe, the viability of the…
View article: The Fate of Unmatched Orthopaedic Applicants
The Fate of Unmatched Orthopaedic Applicants Open
Introduction: Orthopaedic surgery residency has become increasingly competitive for medical school applicants with at least one in five applicants not matching annually. For unmatched applicants, the new application cycle is a perplexing a…
View article: Preoperative dipyridamole-thallium scanning did not reduce 90-day cardiac complications and mortality in patients with femoral neck fractures undergoing hemiarthroplasty
Preoperative dipyridamole-thallium scanning did not reduce 90-day cardiac complications and mortality in patients with femoral neck fractures undergoing hemiarthroplasty Open
Background: Patients with hip fractures have risk factors that increase the likelihood of postoperative cardiac complications and mortality. This study aimed to evaluate the effect of dipyridamole-thallium scanning on 90-day cardiac compli…
View article: CORR Insights®: Disruption of the Gut Microbiome Increases the Risk of Periprosthetic Joint Infection in Mice
CORR Insights®: Disruption of the Gut Microbiome Increases the Risk of Periprosthetic Joint Infection in Mice Open
Where Are We Now? In the current study, Hernandez and colleagues [4] performed a prospective study utilizing a mouse model with a titanium tibial implant that was directly inoculated with bacteria to simulate periprosthetic joint infection…
View article: Clinical and Pathophysiologic Significance of MRI Identified Bone Marrow Lesions Associated with Knee Osteoarthritis.
Clinical and Pathophysiologic Significance of MRI Identified Bone Marrow Lesions Associated with Knee Osteoarthritis. Open
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View article: Issue Information ‐ Editorial Board and TOC
Issue Information ‐ Editorial Board and TOC Open
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View article: 2018 International Consensus Meeting on Musculoskeletal Infection: Research Priorities from the General Assembly Questions
2018 International Consensus Meeting on Musculoskeletal Infection: Research Priorities from the General Assembly Questions Open
Musculoskeletal infections (MSKI) remain the bane of orthopedic surgery, and result in grievous illness and inordinate costs that threaten healthcare systems. As prevention, diagnosis, and treatment has remained largely unchanged over the …
View article: Fever and Erythema are Specific Findings in Detecting Infection Following Total Knee Arthroplasty
Fever and Erythema are Specific Findings in Detecting Infection Following Total Knee Arthroplasty Open
Current diagnostic modalities are based almost exclusively on laboratory findings and the role of clinical presentation remains unknown. The purpose of this study was to examine the diagnostic value of clinical presentation in detecting pe…
View article: Is There a Difference in Infection Risk Between Single and Multiple Doses of Prophylactic Antibiotics? A Meta-analysis
Is There a Difference in Infection Risk Between Single and Multiple Doses of Prophylactic Antibiotics? A Meta-analysis Open
Background The prevention of surgical site infection guidelines issued by the Centers for Disease Control and Prevention (CDC) recently recommended that only a single dose of preoperative antibiotics be administered to patients undergoing …
View article: Integrating RNA expression and visual features for immune infiltrate prediction
Integrating RNA expression and visual features for immune infiltrate prediction Open
Patient responses to cancer immunotherapy are shaped by their unique genomic landscape and tumor microenvironment. Clinical advances in immunotherapy are changing the treatment landscape by enhancing a patient's immune response to eliminat…