Tingbao Zhang
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View article: USP43 promotes cerebral ischemia–reperfusion injury via activation of TAK1
USP43 promotes cerebral ischemia–reperfusion injury via activation of TAK1 Open
View article: Platelet aggregation rate serves as a significant predictive indicator for thromboembolic events in the context of stent-assisted embolization for unruptured arterial aneurysms
Platelet aggregation rate serves as a significant predictive indicator for thromboembolic events in the context of stent-assisted embolization for unruptured arterial aneurysms Open
Background Perioperative cerebrovascular thromboembolic events are serious complications of stent-assisted embolization (SAE) for unruptured intracranial aneurysms (UIAs). To date, there have been no definitive clinical trial results to ef…
View article: Subtemporal approach for posterior communicating artery aneurysms
Subtemporal approach for posterior communicating artery aneurysms Open
Background and objectives Direct visualization of the aneurysmal neck and its related perforating arteries during microsurgical clipping of posterior communicating artery (PCoA) aneurysms with posterior projection or true PCoA aneurysms th…
View article: Study the local metabolic changes of aneurysms through microcatheter sampling
Study the local metabolic changes of aneurysms through microcatheter sampling Open
Intracranial aneurysm is the primary cause of nontraumatic subarachnoid hemorrhage. To assess aneurysm metabolism, we present a method of intra-operatively collecting blood samples from the aneurysm neck, as well as the proximal and distal…
View article: Predicting intraoperative major blood loss in microsurgery for brain arteriovenous malformations
Predicting intraoperative major blood loss in microsurgery for brain arteriovenous malformations Open
Objective Intraoperative blood loss poses a great challenge for brain arteriovenous malformation (AVM) microsurgery, although systematic researches are still lacking. This study aimed to identify factors predicting intraoperative major blo…
View article: Hypomethylated leptin receptor reduces cerebral ischaemia–reperfusion injury by activating the JAK2/STAT3 signalling pathway
Hypomethylated leptin receptor reduces cerebral ischaemia–reperfusion injury by activating the JAK2/STAT3 signalling pathway Open
Objective To investigate the cerebroprotective effects of leptin in vitro and in vivo via the Janus kinase-2 (JAK2)/transcription factor signal transducer and activators of transcription-3 (STAT3) pathway and leptin receptors (LEPR). Metho…
View article: Endovascular embolization for basal ganglia and thalamic arteriovenous malformations
Endovascular embolization for basal ganglia and thalamic arteriovenous malformations Open
Background Basal ganglia and thalamic arteriovenous malformations (AVMs) represent a special subset of malformations. Due to the involvement of vital brain structures and the specifically fine and delicate angioarchitecture of these lesion…
View article: The medical-nursing combined cooperation mechanism of residents-hospital-pension in stitutions-based on tripartite evolutionary game research
The medical-nursing combined cooperation mechanism of residents-hospital-pension in stitutions-based on tripartite evolutionary game research Open
The combination of medical care and nursing enables the elderly to obtain continuous health care and medical services, which can help alleviate the phenomenon of medical resource crowding and make the elderly have a sense of security. This…
View article: Partial Onyx embolization triggers spontaneous regression of cerebral AVM: A case report
Partial Onyx embolization triggers spontaneous regression of cerebral AVM: A case report Open
Spontaneous regression of a cerebral arteriovenous malformations (AVMs) is a rare and poorly understood phenomenon. We present a case of unruptured cerebral AVM in a patient presenting with intermittent headache. In order to reduce hemorrh…
View article: Hybrid surgery recanalization for high-level chronic internal carotid artery occlusion
Hybrid surgery recanalization for high-level chronic internal carotid artery occlusion Open
Objective Although endovascular recanalization is considered a more effective treatment for chronic internal carotid artery occlusion (CICAO), the success rate of complex CICAO remains inadequate. We present hybrid surgery (carotid endarte…
View article: A comparison of Atlas and Leo Baby stents-assisted coiling of intracranial aneurysms with small parent vessels
A comparison of Atlas and Leo Baby stents-assisted coiling of intracranial aneurysms with small parent vessels Open
Background: Some studies have reported the efficacy and safety of the Atlas stent and the Leo Baby stent-assisted coiling (SAC) of intracranial aneurysms arising from small cerebral vessels. The authors aimed to compare the clinical perfor…
View article: Inhibition of the JAK2/STAT3 Signaling Pathway by Piperine Confers Neuroprotection in Rats with Ischemic Stroke
Inhibition of the JAK2/STAT3 Signaling Pathway by Piperine Confers Neuroprotection in Rats with Ischemic Stroke Open
Pepper is a traditional Chinese herbal medicine used for different inflammatory, fever, and bacterial infections. Our previous research shown that the principal pepper active component, piperine, reduces cerebral ischemia-reperfusion (I/R)…
View article: Advances and trends in meningioma research over the last decade: A scientometric and visual analysis
Advances and trends in meningioma research over the last decade: A scientometric and visual analysis Open
Objective We conducted a scientometric and visual analysis of meningioma studies in the past ten years and discussed the current status and trends of meningioma research to provide a reference basis for conducting relevant clinical practic…
View article: Prognostic analysis of posterior fossa decompression with or without cerebellar tonsillectomy for Chiari malformation type I: a multicenter retrospective study
Prognostic analysis of posterior fossa decompression with or without cerebellar tonsillectomy for Chiari malformation type I: a multicenter retrospective study Open
OBJECTIVE The purpose of this study was to compare the prognosis of patients with Chiari malformation type I (CM-I) treated with posterior fossa decompression with duraplasty (PFDD) and posterior fossa decompression with resection of tonsi…
View article: The impact of Allgower-Donati suture pattern and postoperative sweet foods on wound suture breakage in experimental rats
The impact of Allgower-Donati suture pattern and postoperative sweet foods on wound suture breakage in experimental rats Open
View article: Visualization balloon occlusion-assisted technique in the treatment of large or giant paraclinoid aneurysms: A study of 17 cases series
Visualization balloon occlusion-assisted technique in the treatment of large or giant paraclinoid aneurysms: A study of 17 cases series Open
Objective Although balloon-assisted techniques are valuable in aneurysm clipping, repeated angiography and fluoroscopy are required to understand the location and shape of the balloon. This study investigated the value of visualization bal…
View article: Intraoperative Blood Loss in Microsurgery for Brain Arteriovenous Malformations: A Single-Center Retrospective Study
Intraoperative Blood Loss in Microsurgery for Brain Arteriovenous Malformations: A Single-Center Retrospective Study Open
View article: Tubridge flow diverter alone vs. Tubridge flow diverter and coils for the treatment of intracranial aneurysms: A propensity score matching analysis
Tubridge flow diverter alone vs. Tubridge flow diverter and coils for the treatment of intracranial aneurysms: A propensity score matching analysis Open
Background The study was designed to assess the clinical performance of a tubridge flow diverter (TFD) in the treatment of intracranial aneurysms and to compare the efficacy and safety between intracranial aneurysms treated with TFD alone …
View article: Cerebral ischemia after treatment of posterior communicating artery aneurysms: clipping versus coiling
Cerebral ischemia after treatment of posterior communicating artery aneurysms: clipping versus coiling Open
Objection This study aimed to compare the incidence of cerebral ischemia and outcomes between surgical clipping and endovascular coiling in patients with posterior communicating artery (PCoA) aneurysms. Methods Clinical and imaging data of…
View article: [Effectiveness analysis of modified tibial transverse bone transport technique combined with vancomycin calcium phosphate bone cement local filling and covering in treatment of diabetic foot].
[Effectiveness analysis of modified tibial transverse bone transport technique combined with vancomycin calcium phosphate bone cement local filling and covering in treatment of diabetic foot]. Open
Modified tibial transverse bone transport technique combined with vancomycin calcium phosphate bone cement local filling and covering for DF patients can effectively improve the blood supply of the affected limb, promote wound healing, and…
View article: Identification of an Immune-Related Prognostic Signature for Glioblastoma by Comprehensive Bioinformatics and Experimental Analyses
Identification of an Immune-Related Prognostic Signature for Glioblastoma by Comprehensive Bioinformatics and Experimental Analyses Open
Background: Glioblastoma (GBM), which has a poor prognosis, accounts for 31% of all cancers in the brain and central nervous system. There is a paucity of research on prognostic indicators associated with the tumor immune microenvironment …
View article: Identification of Diagnostic Genes and Effective Drugs Associated with Osteoporosis Treatment by Single-Cell RNA-Seq Analysis and Network Pharmacology
Identification of Diagnostic Genes and Effective Drugs Associated with Osteoporosis Treatment by Single-Cell RNA-Seq Analysis and Network Pharmacology Open
Background. Osteoporosis is a common bone metabolic disease with increased bone fragility and fracture rate. Effective diagnosis and treatment of osteoporosis still need to be explored due to the increasing incidence of disease. Methods. S…
View article: Lysosomal-associated transmembrane protein 5 deficiency exacerbates cerebral ischemia/reperfusion injury
Lysosomal-associated transmembrane protein 5 deficiency exacerbates cerebral ischemia/reperfusion injury Open
Lysosomal-associated transmembrane protein 5 (LAPTM5) has been demonstrated to be involved in regulating immunity, inflammation, cell death, and autophagy in the pathophysiological processes of many diseases. However, the function of LAPTM…
View article: Single-Center Retrospective Analysis of Risk Factors for Hydrocephalus After Lateral Ventricular Tumor Resection
Single-Center Retrospective Analysis of Risk Factors for Hydrocephalus After Lateral Ventricular Tumor Resection Open
Objective There is no general consensus on the placement of preoperative and intraoperative external ventricular drainage (EVD) in patients with lateral ventricular tumors (LVTs). The aim of this study was to identify the predictors of pos…
View article: Management of Posterior Fossa Tumors in Adults Based on the Predictors of Postoperative Hydrocephalus
Management of Posterior Fossa Tumors in Adults Based on the Predictors of Postoperative Hydrocephalus Open
Objective This study aims to identify the predictors of postoperative hydrocephalus in patients with posterior fossa tumors (PFTs) and guide the management of perioperative hydrocephalus. Methods We performed a single-institution, retrospe…
View article: Transcriptomic Profiling of Intracranial Arteries in Adult Patients With Moyamoya Disease Reveals Novel Insights Into Its Pathogenesis
Transcriptomic Profiling of Intracranial Arteries in Adult Patients With Moyamoya Disease Reveals Novel Insights Into Its Pathogenesis Open
Moyamoya disease (MMD) is a rare, progressively steno-occlusive cerebrovascular disorder of unknown etiology. Here, we revealed the gene expression profile of the intracranial arteries in MMD via the RNA-sequencing (RNA-seq). We identified…
View article: Intraoperative Monitoring Cerebral Blood Flow During the Treatment of Brain Arteriovenous Malformations in Hybrid Operating Room by Laser Speckle Contrast Imaging
Intraoperative Monitoring Cerebral Blood Flow During the Treatment of Brain Arteriovenous Malformations in Hybrid Operating Room by Laser Speckle Contrast Imaging Open
Background Hemodynamic changes caused by hybrid surgery for brain arteriovenous malformations (bAVM) are usually related to long-term lesions from “blood stealing”. There are currently no viable low-cost, noninvasive procedures for assessi…
View article: Comparison of Sex Differences in Outcomes of Patients With Aneurysmal Subarachnoid Hemorrhage: A Single-Center Retrospective Study
Comparison of Sex Differences in Outcomes of Patients With Aneurysmal Subarachnoid Hemorrhage: A Single-Center Retrospective Study Open
Background Sex differences in the outcomes of patients with aneurysmal subarachnoid hemorrhage (aSAH) remain controversial. The aim of this study was to evaluate sex differences in the outcomes of patients with aSAH. Method This study retr…
View article: Prognostic Role of the Neutrophil-to-Lymphocyte Ratio in Intracerebral Hemorrhage: A Systematic Review and Meta-Analysis
Prognostic Role of the Neutrophil-to-Lymphocyte Ratio in Intracerebral Hemorrhage: A Systematic Review and Meta-Analysis Open
The neutrophil-to-lymphocyte ratio (NLR) plays an important role in the progression of intracerebral hemorrhage (ICH). An increasing number of studies have reported that a high NLR is correlated with poor clinical outcomes among patients w…
View article: Clinical Efficacy of Endoscopic Infratentorial Supracerebellar Approach for Pineal Region Tumors: A Retrospective Case‐Control Study
Clinical Efficacy of Endoscopic Infratentorial Supracerebellar Approach for Pineal Region Tumors: A Retrospective Case‐Control Study Open
Tumors in the pineal region are deep, with complex surrounding anatomy, adjacent to important blood vessels and nerve structures, and surgical resection is difficult and risky. In this paper, we reviewed the literature to understand the ep…