Tinghui Jiang
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View article: ETV4 interacts with LOXL2 to induce epigenetic activation of NID1 during colorectal cancer progression
ETV4 interacts with LOXL2 to induce epigenetic activation of NID1 during colorectal cancer progression Open
Colorectal cancer (CRC) is one of the most common malignant cancers worldwide and its poor prognosis is mainly caused by metastasis. Although extensive studies, the potential molecular mechanisms of CRC metastasis are not fully understood.…
View article: Review of the mechanisms of the biliary-enteric axis in the development of cholangiocarcinoma
Review of the mechanisms of the biliary-enteric axis in the development of cholangiocarcinoma Open
Cholangiocarcinoma (CCA) is a particularly aggressive and challenging type of cancer, known for its poor prognosis, which is worsened by the complex interplay of various biological and environmental factors that contribute to its developme…
View article: Data from ShRNA-Targeted MAP4K4 Inhibits Hepatocellular Carcinoma Growth
Data from ShRNA-Targeted MAP4K4 Inhibits Hepatocellular Carcinoma Growth Open
Purpose: Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) is overexpressed in many types of cancer. Herein, we aimed to investigate its expression pattern, clinical significance, and biological function in hepatocellular ca…
View article: Data from ShRNA-Targeted MAP4K4 Inhibits Hepatocellular Carcinoma Growth
Data from ShRNA-Targeted MAP4K4 Inhibits Hepatocellular Carcinoma Growth Open
Purpose: Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) is overexpressed in many types of cancer. Herein, we aimed to investigate its expression pattern, clinical significance, and biological function in hepatocellular ca…
View article: Supplementary Data from ShRNA-Targeted MAP4K4 Inhibits Hepatocellular Carcinoma Growth
Supplementary Data from ShRNA-Targeted MAP4K4 Inhibits Hepatocellular Carcinoma Growth Open
Supplementary Figures S1-S2; Supplementary Tables S1-S4.
View article: Supplementary Data from ShRNA-Targeted MAP4K4 Inhibits Hepatocellular Carcinoma Growth
Supplementary Data from ShRNA-Targeted MAP4K4 Inhibits Hepatocellular Carcinoma Growth Open
Supplementary Figures S1-S2; Supplementary Tables S1-S4.
View article: E2F2 promotes lung adenocarcinoma progression through B-Myb- and FOXM1-facilitated core transcription regulatory circuitry
E2F2 promotes lung adenocarcinoma progression through B-Myb- and FOXM1-facilitated core transcription regulatory circuitry Open
Lung adenocarcinoma (LUAD) causes severe cancer death worldwide. E2F2 is a canonical transcription factor implicated in transcription regulation, cell cycle and tumorigenesis. The role of E2F2 as well as its transcription regulatory networ…
View article: Clinical verification of vimentin/EpCAM immunolipid magnetic sorting system in monitoring CTCs in arterial and venous blood of advanced tumor
Clinical verification of vimentin/EpCAM immunolipid magnetic sorting system in monitoring CTCs in arterial and venous blood of advanced tumor Open
Background Circulating tumor cells (CTCs) are the dominant factor leading to tumor metastasis. This study aims to investigate the effect of disparate sources of CTCs on the treatment and prognosis of patients with advanced tumors by analyz…
View article: BTG4 is A Novel p53 Target Gene That Inhibits Cell Growth and Induces Apoptosis
BTG4 is A Novel p53 Target Gene That Inhibits Cell Growth and Induces Apoptosis Open
BTG4 is the last cloned and poorly studied member of BTG/Tob family. Studies have suggested that BTG4 is critical for the degradation of maternal mRNAs in mice during the process of maternal-to-zygotic transition, and downregulated in canc…
View article: miR-532-3p Inhibits Proliferation and Promotes Apoptosis of Lymphoma Cells by Targeting β-Catenin
miR-532-3p Inhibits Proliferation and Promotes Apoptosis of Lymphoma Cells by Targeting β-Catenin Open
Background: Dysregulated expression of miR-532-3p has been observed in several types of cancer and plays a key role in tumor progression and metastasis. In this study, we analyzed the role and molecular mechanism of miR-532-3p in lymphoma …
View article: B-Myb Mediates Proliferation and Migration of Non-Small-Cell Lung Cancer via Suppressing IGFBP3
B-Myb Mediates Proliferation and Migration of Non-Small-Cell Lung Cancer via Suppressing IGFBP3 Open
B-Myb has been shown to play an important oncogenic role in several types of human cancers, including non-small-cell lung cancer (NSCLC). We previously found that B-Myb is aberrantly upregulated in NSCLC, and overexpression of B-Myb can si…
View article: MicroRNA-98-5p Inhibits Cell Proliferation and Induces Cell Apoptosis in Hepatocellular Carcinoma via Targeting IGF2BP1
MicroRNA-98-5p Inhibits Cell Proliferation and Induces Cell Apoptosis in Hepatocellular Carcinoma via Targeting IGF2BP1 Open
Some microRNAs (miRs) have been demonstrated to play promoting or tumor-suppressing roles in the development and progression of hepatocellular carcinoma (HCC). However, the regulatory mechanism of miR-98-5p in HCC still remains largely unc…