Tingsheng Qin
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View article: Structural Optimizations on the Scaffold of 7 <i>H</i> ‐Pyrrolo[2,3‐ <i>d</i> ]Pyrimidine to Develop Potent iNOS Inhibitors With Improved Antiarthritis Activity In Vivo
Structural Optimizations on the Scaffold of 7 <i>H</i> ‐Pyrrolo[2,3‐ <i>d</i> ]Pyrimidine to Develop Potent iNOS Inhibitors With Improved Antiarthritis Activity In Vivo Open
Inducible nitric oxide synthase (iNOS) is an attractive target to develop drugs for the treatment of rheumatoid arthritis (RA), whose overexpression leads to the release of abundant NO. In this study, a series of compounds were designed an…