Explanipedia

The escalating burden of osteoarthritis in East and Southeast Asia: an information-analytical study from the GBD 2021 Open

Jinlei Zhou, Yuan Zhang, Sishen Xie, Yanlei Li, Qice Sun , et al. · 2025

Preoperative Prognostic Nutritional Index as a Useful Tool for Predicting Postoperative Delirium in Elderly Patients with Degenerative Lumbar Diseases Open

Jinlei Zhou, Jing Tang, Sishen Xie, Haiyu Shao, Chen Xia , et al. · 2025

The preoperative use of PNI holds promise as a valuable tool for assessing the risk of POD in elderly patients undergoing TLIF.

Mapping the field of spondylolisthesis: A bibliometric analysis Open

Jingwen Xu, Yong Li, Tingxiao Zhao, Wei‐Yi Wu, Xinwen Yang , et al. · 2025

BACKGROUND In recent years, the number of studies on spondylolisthesis has been increasing, and there are many publications on this disorder. To our knowledge, there is no bibliometric analysis of spondylolisthesis to date. AIM To investig…

Accelerated global burden of depressive disorders during the COVID-19 pandemic from 2019 to 2021 Open

Jinlei Zhou, Yuan Zhang, Shuangshuang He, Sen Xu, Quan Sun , et al. · 2025

A thorough and current analysis of the burden and evolving trends in depressive disorders during the COVID-19 pandemic from 2019 to 2021 remains unavailable. Employing the Global Burden of Disease (GBD) 2021 database, we evaluated the burd…

Uridine-cytidine kinase 2 is correlated with immune, DNA damage repair and promotion of cancer stemness in pan-cancer Open

Jinlong Tian, Yanlei Li, Tong Yu, Yuan Zhang, Tingxiao Zhao , et al. · 2025

Background UCK2 (Uridine-Cytidine Kinase 2) is a promising prognostic marker for malignant tumors, but its association with immune infiltration and cancer stemness in pan-cancer remains to be fully understood. we find that gene UCK2 is clo…

Association between daily sitting time and sarcopenia in the US population: a cross-sectional study Open

Alei Zhang, Yanlei Li, Jinlei Zhou, Yuan Zhang, Sishen Xie , et al. · 2025

Our research has found that increased sedentary time significantly increases the risk of sarcopenia, especially among non-Hispanic white men with lower BMI. Additionally, individuals who lack vigorous physical activity also have a higher p…

From Pain to Progress: Comprehensive Analysis of Musculoskeletal Disorders Worldwide Open

Jinlei Zhou, Sishen Xie, Sen Xu, Yuan Zhang, Y.G. Li , et al. · 2024

From 1990 to 2021, the burden of MSDs has been concentrated in high SDI regions, with a gradual shift towards low and middle SDI regions.

Unraveling the role of bisphenol A in osteosarcoma biology: insights into prognosis and immune microenvironment modulation Open

Liao Shiyao, Kang Yao, LV Jun, Lin Yichen, Tingxiao Zhao , et al. · 2024

Our study highlighted the significant association of BPA with OS biology, particularly in its potential role in modulating the tumor immune microenvironment. We offered a fresh insight into the influence of BPA on cancer development, thus …

Does autoimmune diseases increase the risk of frailty? A Mendelian randomization study Open

Jinlei Zhou, Yuan Zhang, Ting Ni, Yanlei Li, Haiyu Shao , et al. · 2024

Background The causality of autoimmune diseases with frailty has not been firmly established. We conducted this Mendelian randomization (MR) study to unveil the causal associations between autoimmune diseases with frailty. Methods A MR ana…

Effect of Tranexamic Acid on Hidden Blood Loss in Percutaneous Endoscopic Transforaminal Lumbar Interbody Fusion: A Retrospective Study Open

Yanlei Li, Meng Ge, Jinlong Tian, Jinlei Zhou, Yao Kang , et al. · 2024

Research has found that there is a significant amount of HBL in patients undergoing PE-TLIF. Intravenous injection of TXA can safely and effectively reduce perioperative HBL and VBL. Additionally, compared to the control group, the TXA gro…

The genetic causal association between hip or knee osteoarthritis and frailty: a two-sample Mendelian randomization analysis Open

Jinlei Zhou, Yanlei Li, Yanze Lin, Fei Wang, Jinlong Tian , et al. · 2024

Introduction Osteoarthritis of the hip or knee has been reported to be linked to an increased risk of frailty. However, a definitive conclusion about whether hip or knee osteoarthritis increases susceptibility to frailty remains elusive. M…

Comprehensive Analysis of Fbxo43 Expression and its Prognostic and Therapeutic Implications in Osteosarcoma Open

Jiang Jin, Yao Kang, Tingxiao Zhao, Yao Longtao, Yanlei Li , et al. · 2024

Preoperative prognostic nutritional index and systemic immune inflammation index for predicting the efficacy and survival time of patients with osteosarcoma undergoing neoadjuvant chemotherapy combined with surgery Open

Jin Jiang, Tingxiao Zhao, Longtao Yao, Tao Zhang, Lichen Ji , et al. · 2024

Enneking stage, PNI, and SII levels were risk factors for poor efficacy in patients with osteosarcoma after NACT combined with surgery. Patients whose PNI level was low and SII level was high presented poor prognosis following the treatmen…

Correction: Multidimensional analysis to elucidate the possible mechanism of bone metastasis in breast cancer Open

Kang Yao, Xiaojun Zhu, Tingxiao Zhao, Liao Shiyao, Ji Lichen , et al. · 2023

Multidimensional analysis to elucidate the possible mechanism of bone metastasis in breast cancer Open

Kang Yao, Xiaojun Zhu, Tingxiao Zhao, Liao Shiyao, Ji Lichen , et al. · 2023

Global trends and frontiers of research on total disc replacement: A bibliometric analysis Open

Yanlei Li, Jinlong Tian, Jiongnan Xu, Meng Ge, Haiyu Shao , et al. · 2023

With the increased risk of complications associated with traditional spinal fusion for the treatment of degenerative disc disease, total disc replacement (TDR) has received increasing attention in recent years. Despite the rapid developmen…

Unraveling the relationship between serum parathyroid hormone levels and trabecular bone score: a cross-sectional study Open

Tingxiao Zhao, Yanlei Li, Jinlong Tian, Jiongnan Xu, Fanfan Zhao , et al. · 2023

Background: The TBS is a new method for clinicians to assess bone quality. It is directly related to the mechanical strength of bone and helps predict fracture risk. The present analysis aimed to the associations between serum PTH level an…

LINC00482 sponged miR-2467-3p to promote bone metastasis of prostate cancer through activating Wnt/β-catenin signaling pathway Open

Shiyao Liao, Xuemei Fang, Kai Zhou, Tingxiao Zhao, Lichen Ji , et al. · 2023

Determining the learning curve for percutaneous endoscopic lumbar interbody fusion for lumbar degenerative diseases Open

Tingxiao Zhao, Zhanqiu Dai, Jun Zhang, Yazeng Huang, Haiyu Shao · 2023

Purpose Percutaneous endoscopic lumbar interbody fusion (PELIF) is one of the least invasive procedures for lumbar degenerative disorders (LDD). There is limited knowledge of the learning curve for PELIF. Methods A total of 93 consecutive …

Bibliometric Analysis of the Scientific Literature on Spondylolisthesis Based of Web of Science Open

Jiongnan Xu, Yong Li, Tingxiao Zhao, Zhanqiu Dai, Qixin Xia , et al. · 2023

Relationship between sarcopenia/paravertebral muscles and the incidence of vertebral refractures following percutaneous kyphoplasty: a retrospective study Open

Qi Chen, Chenyang Lei, Tingxiao Zhao, Zhanqiu Dai, Jun Zhang , et al. · 2022

Osteoporosis, fracture and survival: Application of machine learning in breast cancer prediction models Open

Lichen Ji, Wei Zhang, Xugang Zhong, Tingxiao Zhao, Xixi Sun , et al. · 2022

The risk of osteoporosis in breast cancer patients is higher than that in healthy populations. The fracture and death rates increase after patients are diagnosed with osteoporosis. We aimed to develop machine learning-based models to predi…

A Worldwide Bibliometric Analysis of Published Literature on Osteoporosis Vertebral Compression Fracture Open

Yanlei Li, Jinlong Tian, Ge Meng, Lichen Ji, Kang Yao , et al. · 2022

This study represents an updated bibliometric analysis of OVCF. The aim is to identify current research hotspots and future trends to guide clinicians and researchers in this field.

A Worldwide Bibliometric Analysis of Tetrandrine Research in Recent Two Decades Open

Guang Yang, Wenqing Xie, Yilan Ding, Weiyang Wang, Cheng Zhi Huang , et al. · 2022

Background: Tetrandrine has been the focus of many studies in recent years. Currently, no bibliometric study in this field has been published. This study presents a bibliometric analysis of the articles on tetrandrine research from the WOS…

Relationship between sarcopenia/paravertebral muscles and the incidence of vertebral refractures following percutaneous kyphoplasty: A retrospective study Open

Qi Chen, Chenyang Lei, Tingxiao Zhao, Zhanqiu Dai, Jun Zhang , et al. · 2022

Background This study aimed to reveal the associations of osteoporotic vertebral compression refracture (OVCRF) incidence with sarcopenia and paravertebral muscles (PVM). Methods A total of 214 elderly patients who underwent percutaneous k…

Osteoclasts differential-related prognostic biomarker for osteosarcoma based on single cell, bulk cell and gene expression datasets Open

Haiyu Shao, Meng Ge, Jun Zhang, Tingxiao Zhao, Shuijun Zhang · 2022

Osteoporosis, Fracture and Survival: Application of Machine Learning in Breast Cancer Prediction Models Open

Lichen Ji, Wei Zhang, Xugang Zhong, Tingxiao Zhao, Xixi Sun , et al. · 2022

Additional file 1 of Relationship between sarcopenia/paravertebral muscles and the incidence of vertebral refractures following percutaneous kyphoplasty: a retrospective study Open

Qi Chen, Chenyang Lei, Tingxiao Zhao, Zhanqiu Dai, Jun Zhang , et al. · 2022

Additional file 1.

Identification and Validation of the Prognostic Stemness Biomarkers in Bladder Cancer Bone Metastasis Open

Yao Kang, Xiaojun Zhu, Xijun Wang, Shiyao Liao, Mengran Jin , et al. · 2021

Background Bladder urothelial carcinoma (BLCA) is one of the most common urinary system malignancies with a high metastasis rate. Cancer stem cells (CSCs) play an important role in the occurrence and progression of BLCA, however, its roles…

miRNA-296-5p functions as a potential tumor suppressor in human osteosarcoma by targeting SND1 Open

Yazeng Huang, Jun Zhang, Jianjian Shen, Tingxiao Zhao, Youjia Xu · 2021

Background: The pathogenesis of osteosarcoma (OS) is still unclear, and it is still necessary to find new targets and drugs for anti-OS. This study aimed to investigate the role and mechanism of the anti-OS effects of miR-296-5p. Methods: …

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