Tiny M. Hlokwe
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View article: Low Seroprevalence of Bovine Brucellosis in Communal Areas of Limpopo Province, South Africa
Low Seroprevalence of Bovine Brucellosis in Communal Areas of Limpopo Province, South Africa Open
Brucellosis is caused by Gram-negative coccobacilli of the Brucella genus, with cattle mainly infected with Brucella abortus. The disease burden is a threat to socioeconomic development (agriculture/tourism) as well as to animal health, bi…
View article: Are there benefits of culture-based detection of Mycobacterium avium spp paratuberculosis over histopathology?
Are there benefits of culture-based detection of Mycobacterium avium spp paratuberculosis over histopathology? Open
Paratuberculosis (Johne’s disease) has devastating outcomes on ruminant health and impacts on national and international trade. The current work assessed the diagnostic value of the VersaTREK automated liquid culture system in isolating My…
View article: The Presence of esat-6 and cfp10 and Other Gene Orthologs of the RD 1 Region in Non-Tuberculous Mycobacteria, Mycolicibacteria, Mycobacteroides and Mycolicibacter as Possible Impediments for the Diagnosis of (Animal) Tuberculosis
The Presence of esat-6 and cfp10 and Other Gene Orthologs of the RD 1 Region in Non-Tuberculous Mycobacteria, Mycolicibacteria, Mycobacteroides and Mycolicibacter as Possible Impediments for the Diagnosis of (Animal) Tuberculosis Open
The Esx-1 family proteins of the Type VII secretion systems of Mycobacterium bovis and Mycobacterium tuberculosis have been assessed and are frequently used as candidates for tuberculosis (TB) diagnosis in both humans and animals. The pres…
View article: Absence of Tuberculosis‐Causing <i>Mycobacteria</i> from Slaughtered Livestock Tissues and Environmental Samples, Gauteng Province, South Africa
Absence of Tuberculosis‐Causing <i>Mycobacteria</i> from Slaughtered Livestock Tissues and Environmental Samples, Gauteng Province, South Africa Open
Mycobacterium tuberculosis complex (MTBC) is a group of bacteria responsible for causing tuberculosis in animals and humans. In South Africa (S.A), slaughterhouses are registered by the government and closely inspected and audited for hygi…
View article: Seroprevalence of brucellosis in communal and smallholder cattle farming in North West Province, South Africa
Seroprevalence of brucellosis in communal and smallholder cattle farming in North West Province, South Africa Open
Brucellosis is an important bacterial zoonosis responsible for considerable economic losses in livestock and health-related burden worldwide. The objective of this study was to determine the seroprevalence of brucellosis in communal and sm…
View article: Antimycobacterial, hepatoprotective and cytotoxicity effects of selected plant species from the Menispermaceae family
Antimycobacterial, hepatoprotective and cytotoxicity effects of selected plant species from the Menispermaceae family Open
Tuberculosis, caused by Mycobacterium tuberculosis, is a worldwide disease affecting millions of people. The rise of resistant strains, coupled with toxicity of current chemotherapy, requires effective alternatives against mycobacterial in…
View article: Application of the gamma‐interferon assay to determine the prevalence of bovine tuberculosis in slaughter livestock at abattoirs in Gauteng, South Africa
Application of the gamma‐interferon assay to determine the prevalence of bovine tuberculosis in slaughter livestock at abattoirs in Gauteng, South Africa Open
Background Bovine tuberculosis (bTB) is a zoonotic disease with great economic impact estimated at billions of dollars annually worldwide. Meat inspection represents a long‐standing form of disease surveillance that serves both food safety…
View article: Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa
Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa Open
Background Bovine tuberculosis (bTB) affects cattle and wildlife in South Africa with the African buffalo ( Syncerus caffer ) as the principal maintenance host. The presence of a wildlife maintenance host at the wildlife/livestock interfac…
View article: Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa
Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa Open
Background: Bovine tuberculosis (bTB) affects cattle and wildlife in South Africa with the African buffalo (Syncerus caffer) as the principal maintenance host. The presence of a wildlife maintenance host at the wildlife/livestock interface…
View article: Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa
Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa Open
Background Bovine tuberculosis (bTB) affects cattle and wildlife in South Africa with the African buffalo ( Syncerus caffer ) as the principal maintenance host. The presence of a wildlife maintenance host at the wildlife/livestock interfac…
View article: Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa
Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa Open
Background Bovine tuberculosis (bTB) affects cattle and wildlife in South Africa with the African buffalo ( Syncerus caffer ) as the principal maintenance host. The presence of a wildlife maintenance host at the wildlife/livestock interfac…
View article: Genetic profiling of Mycobacterium bovis strains from slaughtered cattle in Eritrea
Genetic profiling of Mycobacterium bovis strains from slaughtered cattle in Eritrea Open
Mycobacterium bovis (M.bovis) is the main causative agent for bovine tuberculosis (BTB) and can also be the cause of zoonotic tuberculosis in humans. In view of its zoonotic nature, slaughterhouse surveillance, potentially resulting in tot…
View article: Mycobacterium tuberculosis infection in cattle from the Eastern Cape Province of South Africa
Mycobacterium tuberculosis infection in cattle from the Eastern Cape Province of South Africa Open
This is the first report of cases of M. tuberculosis infection in cattle in South Africa. The VNTR profiles of the M. tuberculosis strains identified in the current study will form the basis for creating M. tuberculosis VNTR database for a…
View article: Non-tuberculous Mycobacteria in South African Wildlife: Neglected Pathogens and Potential Impediments for Bovine Tuberculosis Diagnosis
Non-tuberculous Mycobacteria in South African Wildlife: Neglected Pathogens and Potential Impediments for Bovine Tuberculosis Diagnosis Open
Non-tuberculous mycobacteria (NTM) are not only emerging and opportunistic pathogens of both humans and animals, but from a veterinary point of view some species induce cross-reactive immune responses that hamper the diagnosis of bovine tu…
View article: Isolation and molecular characterization of Mycobacterium bovis causing pulmonary tuberculosis and epistaxis in a Thoroughbred horse
Isolation and molecular characterization of Mycobacterium bovis causing pulmonary tuberculosis and epistaxis in a Thoroughbred horse Open
This report indicates that horses may contract and harbour M. bovis despite their lower susceptibility compared to other domestic animals. It also suggests that the infection may be more easily contained and eliminated from the host.
View article: WILDLIFE ON THE MOVE: A HIDDEN TUBERCULOSIS THREAT TO CONSERVATION AREAS AND GAME FARMS THROUGH INTRODUCTION OF UNTESTED ANIMALS
WILDLIFE ON THE MOVE: A HIDDEN TUBERCULOSIS THREAT TO CONSERVATION AREAS AND GAME FARMS THROUGH INTRODUCTION OF UNTESTED ANIMALS Open
In South Africa, African buffaloes ( Syncerus caffer ) are one of the wildlife maintenance hosts for bovine tuberculosis (BTB) and play a key role in the spread of the disease to other wildlife species and potentially back to cattle. We re…
View article: Longevity of Mycobacterium bovis in Raw and Traditional Souring Milk as a Function of Storage Temperature and Dose
Longevity of Mycobacterium bovis in Raw and Traditional Souring Milk as a Function of Storage Temperature and Dose Open
This study demonstrates that M. bovis may survive in fresh and souring milk for periods of time that represent a risk of exposure to people consuming these products, as well as domestic or wild animal populations that have reported opportu…
View article: Spillover of<i>Mycobacterium bovis</i>from Wildlife to Livestock, South
Africa
Spillover of<i>Mycobacterium bovis</i>from Wildlife to Livestock, South
Africa Open
During August 2012-February 2013, bovine tuberculosis was detected in communal livestock bordering the Greater Kruger National Park Complex (GKNPC) in South Africa. Using spacer oligonucleotide and variable number tandem repeat typing, we …