Tiphaine Raia‐Barjat
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View article: Amniotic Fluid PROK1 Profiling and Its Association with Infectious Preterm Birth
Amniotic Fluid PROK1 Profiling and Its Association with Infectious Preterm Birth Open
Prokineticin 1 (PROK1), known as EG-VEGF, is a key regulator of pregnancy, playing a crucial role from implantation to birth. Our studies have shown that circulating concentrations of PROK1 are highest during the first trimester and are el…
View article: Antagonisation of Prokineticin Receptor‐2 Attenuates Preeclampsia Symptoms
Antagonisation of Prokineticin Receptor‐2 Attenuates Preeclampsia Symptoms Open
Preeclampsia (PE) is the most threatening pathology of human pregnancy. Placenta from PE patients releases harmful factors that contribute to the exacerbation of the disease. Among these factors is the prokineticin1 (PROK1) and its recepto…
View article: Restricted fetal blood brain barrier permeability in a preclinical model of autism induced by Group B <i>Streptococcus</i> maternal immune activation
Restricted fetal blood brain barrier permeability in a preclinical model of autism induced by Group B <i>Streptococcus</i> maternal immune activation Open
Clinical and preclinical data about perinatal inflammation show its implication in brain injuries leading to autism spectrum disorder (ASD). For instance, Group B Streptococcus (GBS) chorioamnionitis generates autistic manifestations in th…
View article: A multidisciplinary and structured investigation of three suspected clusters of transverse upper limb reduction defects in France
A multidisciplinary and structured investigation of three suspected clusters of transverse upper limb reduction defects in France Open
View article: Corrigendum: Serum D-dimer is not predictive of placenta-mediated complications in pregnancy at high risk: the multicentric prospective cohort AngioPred study
Corrigendum: Serum D-dimer is not predictive of placenta-mediated complications in pregnancy at high risk: the multicentric prospective cohort AngioPred study Open
[This corrects the article DOI: 10.3389/fcell.2023.1115622.].
View article: Endometrial biopsy performed before the first in vitro fertilization does not impact the early pregnancy rate
Endometrial biopsy performed before the first in vitro fertilization does not impact the early pregnancy rate Open
View article: EG-VEGF maternal levels predict spontaneous preterm birth in the second and third trimesters in pregnant women with risk factors for placenta-mediated complications
EG-VEGF maternal levels predict spontaneous preterm birth in the second and third trimesters in pregnant women with risk factors for placenta-mediated complications Open
Prediction of spontaneous preterm birth in asymptomatic women remains a great challenge for the public health system. The aim of the study was to determine the informational value of EG-VEGF circulating levels for prediction of spontaneous…
View article: Impact of discontinuing oxytocin in active labour on neonatal morbidity: an open-label, multicentre, randomised trial
Impact of discontinuing oxytocin in active labour on neonatal morbidity: an open-label, multicentre, randomised trial Open
View article: The Multifaceted Functions of Prion Protein (PrPC) in Cancer
The Multifaceted Functions of Prion Protein (PrPC) in Cancer Open
The cellular prion protein (PrPC) is a glycoprotein anchored to the cell surface by glycosylphosphatidylinositol (GPI). PrPC is expressed both in the brain and in peripheral tissues. Investigations on PrPC’s functions revealed its direct i…
View article: EG-VEGF Maternal levels predict spontaneous preterm birth in the second and third trimesters of pregnancy
EG-VEGF Maternal levels predict spontaneous preterm birth in the second and third trimesters of pregnancy Open
Background: Prediction of spontaneous preterm birth in asymptomatic women remains a great challenge for the public health system. The aim of the study was to determine the informational value of EG-VEGF circulating levels in pregnant women…
View article: Classification Performance of the Ages and Stages Questionnaire: Influence of Maternal Education Level
Classification Performance of the Ages and Stages Questionnaire: Influence of Maternal Education Level Open
(1) Background: The Ages and Stages Questionnaire—Third Edition (ASQ-3) is a parental screening questionnaire increasingly being used to evaluate the development of preterm children. We aimed to assess the classification performance of the…
View article: Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus Vaccine (RSVPreF3) in Mothers and Their Infants: A Phase 2 Randomized Trial
Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus Vaccine (RSVPreF3) in Mothers and Their Infants: A Phase 2 Randomized Trial Open
Background In a phase 1/2 study, a maternal respiratory syncytial virus vaccine candidate (RSVPreF3) demonstrated an acceptable safety profile and efficiently increased RSV-specific humoral immune responses in non-pregnant women. Methods I…
View article: Perinatal inflammation exposure and developmental outcomes 7 years after neonatal arterial ischaemic stroke
Perinatal inflammation exposure and developmental outcomes 7 years after neonatal arterial ischaemic stroke Open
Aim To test the association between perinatal inflammation exposure and Full‐Scale IQ (FSIQ) score 7 years after neonatal arterial ischaemic stroke (NAIS). Method We conducted a cross‐sectional ancillary study nested in a multicentric long…
View article: Serum D-dimer is not predictive of placenta-mediated complications in pregnancy at high risk: The multicentric prospective cohort AngioPred study
Serum D-dimer is not predictive of placenta-mediated complications in pregnancy at high risk: The multicentric prospective cohort AngioPred study Open
Background: The theory that D-dimer level might has a predictive or diagnostic role in preeclampsia needs to be explored. Aim of the study was to evaluate the association between serum D-dimer level and the occurrence of placenta-mediated …
View article: Fetal Movement Counting in Prolonged Pregnancies: The COMPTAMAF Prospective Randomized Trial
Fetal Movement Counting in Prolonged Pregnancies: The COMPTAMAF Prospective Randomized Trial Open
In prolonged pregnancies, the risks of neonatal morbidity and mortality are increased. The aim of this trial was to assess the benefits of maternal information about fetal movement (FM) counting on neonatal outcomes in prolonged pregnancy.…
View article: Uterine transarterial embolization as nonsurgical management for uterine rupture following vaginal delivery: A report of two cases
Uterine transarterial embolization as nonsurgical management for uterine rupture following vaginal delivery: A report of two cases Open
View article: Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial
Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial Open
View article: Performance of Indocyanine Green Compared to 99mTc-Nanocolloids for Sentinel Lymph Node Detection in Early Vulvar Cancer
Performance of Indocyanine Green Compared to 99mTc-Nanocolloids for Sentinel Lymph Node Detection in Early Vulvar Cancer Open
Study objective: The aim of this study was to evaluate the performance of indocyanine green (ICG) compared to that of the gold standard 99mtechnetium (99mTc-nanocolloids) in detecting sentinel lymph nodes (SLN) in early vulvar cancer. Mate…
View article: Venous Thromboembolism Risk Score and Pregnancy
Venous Thromboembolism Risk Score and Pregnancy Open
Venous thromboembolism (VTE) is a major contributor to maternal morbidity and mortality worldwide. Pregnancy is associated with the development of a baseline hypercoagulable state. The two strongest risk factors for pregnancy-associated VT…
View article: Animal Models of Chorioamnionitis: Considerations for Translational Medicine
Animal Models of Chorioamnionitis: Considerations for Translational Medicine Open
Preterm birth is defined as any birth occurring before 37 completed weeks of gestation by the World Health Organization. Preterm birth is responsible for perinatal mortality and long-term neurological morbidity. Acute chorioamnionitis is o…
View article: Preeclampsia and Venous Thromboembolism: Pathophysiology and Potential Therapy
Preeclampsia and Venous Thromboembolism: Pathophysiology and Potential Therapy Open
Preeclampsia (PET) is a multisystem inflammatory disorder that represents a leading cause of feto-maternal morbidity and mortality, complicating 2–5% of all pregnancies. PET incurs an increased risk of venous thromboembolism, which is one …
View article: Role of NLRP7 in Normal and Malignant Trophoblast Cells
Role of NLRP7 in Normal and Malignant Trophoblast Cells Open
Gestational choriocarcinoma (CC) is an aggressive cancer that develops upon the occurrence of abnormal pregnancies such as Hydatidiform moles (HMs) or upon non-molar pregnancies. CC cells often metastasize in multiple organs and can cause …
View article: Pain and Satisfaction in Women Induced by Vaginal Dinoprostone, Double Balloon Catheter and Oral Misoprostol
Pain and Satisfaction in Women Induced by Vaginal Dinoprostone, Double Balloon Catheter and Oral Misoprostol Open
View article: Republication de : recommandations formalisées d’experts. Prise en charge de la patiente avec une pré-éclampsie sévère–RFE communes Société française d’anesthésie-réanimation (SFAR)–Collège national des gynécologues et obstétriciens français (CGNOF)
Republication de : recommandations formalisées d’experts. Prise en charge de la patiente avec une pré-éclampsie sévère–RFE communes Société française d’anesthésie-réanimation (SFAR)–Collège national des gynécologues et obstétriciens français (CGNOF) Open
View article: Vitamin D deficiency during late pregnancy mediates placenta-associated complications
Vitamin D deficiency during late pregnancy mediates placenta-associated complications Open
View article: Premier Rapport sur les Agénésies Transverses des Membres Supérieurs (ATMS) : saisine n° 2018-SA-0242 « Demande d'avis relatif à l'existence de cas groupés d'agénésie transverse des membres supérieurs dans des zones géographiques restreintes de trois départements (Ain, Morbihan et Loire-Atlantique) »
Premier Rapport sur les Agénésies Transverses des Membres Supérieurs (ATMS) : saisine n° 2018-SA-0242 « Demande d'avis relatif à l'existence de cas groupés d'agénésie transverse des membres supérieurs dans des zones géographiques restreintes de trois départements (Ain, Morbihan et Loire-Atlantique) » Open
Entre 2010 et 2015, des naissances groupées d'enfants porteurs d'une agénésie transverse des membres supérieurs (ATMS) ont été signalées dans trois départements, l'Ain, la Loire Atlantique et le Morbihan. Afin de répondre aux questionnemen…
View article: Umbilical cord thrombosis and chorioamnionitis in neonatal arterial ischaemic stroke
Umbilical cord thrombosis and chorioamnionitis in neonatal arterial ischaemic stroke Open
A baby boy was delivered at term by emergency caesarean section because of abnormal fetal heart rate patterns during spontaneous labour. The umbilical cord arterial blood obtained at delivery had a pH of 6.97 and a lactate concentration of…
View article: Midwives’ attitudes toward participation of pregnant women in a preventive vaccine hypothetical clinical trial
Midwives’ attitudes toward participation of pregnant women in a preventive vaccine hypothetical clinical trial Open
Introduction Pregnant women are frequently excluded from clinical trials. Yet, inclusion of pregnant women is of interest in vaccinology including during health crisis. Promotion of clinical trials by midwives may facilitate the decision m…
View article: Research Projects in Obstetrics and Gynecology in France: How Is Functionning the Ethical Review Board (Comité D’Ethique Pour La Recherche En Obstétrique Et Gynécologie) (CEROG)&nbsp;?
Research Projects in Obstetrics and Gynecology in France: How Is Functionning the Ethical Review Board (Comité D’Ethique Pour La Recherche En Obstétrique Et Gynécologie) (CEROG) ? Open
View article: The Emerging Role of the Prokineticins and Homeobox Genes in the Vascularization of the Placenta: Physiological and Pathological Aspects
The Emerging Role of the Prokineticins and Homeobox Genes in the Vascularization of the Placenta: Physiological and Pathological Aspects Open
Vasculogenesis and angiogenesis are key processes of placental development, which occur throughout pregnancy. Placental vasculogenesis occurs during the first trimester of pregnancy culminating in the formation of hemangioblasts from intra…