Tirin Moore
YOU?
Author Swipe
View article: Selective control of prefrontal neural timescales by parietal cortex - After 1st revision
Selective control of prefrontal neural timescales by parietal cortex - After 1st revision Open
Intrinsic neural timescales quantify how long spontaneous neuronal activity patterns persist, reflecting dynamics of endogenous fluctuations. We measured intrinsic timescales of frontal eye field (FEF) neurons in rhesus macaques and examin…
View article: Pupil size predicts exploration through critical slowing in prefrontal dynamics
Pupil size predicts exploration through critical slowing in prefrontal dynamics Open
In uncertain environments, intelligent decision-makers exploit actions that have been rewarding in the past, but also explore actions that could be better. Several studies link exploration to pupil size—a peripheral correlate of neuromodul…
View article: Neuropixels reveal structure-function relationships in monkey V1 <i>in vivo</i>
Neuropixels reveal structure-function relationships in monkey V1 <i>in vivo</i> Open
The relationship between structural properties of diverse neuronal populations in monkey primary visual cortex (V1) and their in vivo functional responses is not fully understood. We combined high-density Neuropixels recordings across cort…
View article: Robust encoding of stimulus–response mapping by neurons in visual cortex
Robust encoding of stimulus–response mapping by neurons in visual cortex Open
Neural activity in sensory cortex is modulated by behavioral and cognitive factors, and this modulation is thought to contribute to the selection of specific sensory information needed to achieve behavioral goals. In contrast, more abstrac…
View article: Dependence of Contextual Modulation in Macaque V1 on Interlaminar Signal Flow
Dependence of Contextual Modulation in Macaque V1 on Interlaminar Signal Flow Open
In visual cortex, neural correlates of subjective perception can be generated by modulation of activity from beyond the classical receptive field (CRF). In macaque V1, activity generated by nonclassical receptive field (nCRF) stimulation i…
View article: Dependence of Contextual Modulation in Macaque V1 on Interlaminar Signal Flow
Dependence of Contextual Modulation in Macaque V1 on Interlaminar Signal Flow Open
In visual cortex, neural correlates of subjective perception can be generated by modulation of activity from beyond the classical receptive field (CRF). In macaque V1, activity generated by nonclassical receptive field (nCRF) stimulation i…
View article: Neural mechanisms underlying robust target selection in response to microstimulation of the oculomotor system
Neural mechanisms underlying robust target selection in response to microstimulation of the oculomotor system Open
Despite its prevalence in studying the causal roles of different brain circuits in cognitive processes, electrical microstimulation often results in inconsistent behavioral effects. These inconsistencies are assumed to be due to multiple m…
View article: Selective control of prefrontal neural timescales by parietal cortex
Selective control of prefrontal neural timescales by parietal cortex Open
Intrinsic neural timescales quantify how long spontaneous neuronal activity patterns persist, reflecting dynamics of endogenous fluctuations. We measured intrinsic timescales of frontal eye field (FEF) neurons and examined their changes du…
View article: Comparison of orientation encoding across layers within single columns of primate V1 revealed by high-density recordings
Comparison of orientation encoding across layers within single columns of primate V1 revealed by high-density recordings Open
Primary visual cortex (V1) has been the focus of extensive neurophysiological investigations, with its laminar organization serving as a crucial model for understanding the functional logic of neocortical microcircuits. Utilizing newly dev…
View article: Dependence of Contextual Modulation in Macaque V1 on Interlaminar Signal Flow
Dependence of Contextual Modulation in Macaque V1 on Interlaminar Signal Flow Open
In visual cortex, neural correlates of subjective perception can be generated by modulation of activity from beyond the classical receptive field (CRF). In macaque V1, activity generated by nonclassical receptive field (nCRF) stimulation i…
View article: Dissociable components of attention exhibit distinct neuronal signatures in primate visual cortex
Dissociable components of attention exhibit distinct neuronal signatures in primate visual cortex Open
Attention can be deployed in multiple forms and facilitates behavior by influencing perceptual sensitivity and choice bias. Attention is also associated with a myriad of changes in sensory neural activity. Yet, the relationship between the…
View article: Dissociating the Contributions of Frontal Eye Field Activity to Spatial Working Memory and Motor Preparation
Dissociating the Contributions of Frontal Eye Field Activity to Spatial Working Memory and Motor Preparation Open
Neurons within dorsolateral prefrontal cortex (PFC) of primates are characterized by robust persistent spiking activity exhibited during the delay period of working memory tasks. This includes the frontal eye field (FEF) where nearly half …
View article: Cue-specific neuronal ensembles span intermittent rate coding of working memory
Cue-specific neuronal ensembles span intermittent rate coding of working memory Open
Persistent, memorandum-specific neuronal spiking activity has long been hypothesized to underlie working memory. However, emerging evidence suggests a possible role for ‘activity-silent’ synaptic mechanisms. This issue remains controversia…
View article: Editor's evaluation: Uncovering circuit mechanisms of current sinks and sources with biophysical simulations of primary visual cortex
Editor's evaluation: Uncovering circuit mechanisms of current sinks and sources with biophysical simulations of primary visual cortex Open
Full text Figures and data Side by side Abstract Editor's evaluation Introduction Results Discussion Materials and methods Appendix 1 Data availability References Decision letter Author response Article and author information Metrics Abstr…
View article: Dissociating the Contributions of Frontal Eye Field Activity to Spatial Working Memory and Motor Preparation
Dissociating the Contributions of Frontal Eye Field Activity to Spatial Working Memory and Motor Preparation Open
Neurons within dorsolateral prefrontal cortex of primates are characterized by robust persistent spiking activity exhibited during the delay period of working memory tasks. This includes the frontal eye field (FEF) where nearly half of the…
View article: Pupil size predicts the onset of exploration and changes in prefrontal dynamics
Pupil size predicts the onset of exploration and changes in prefrontal dynamics Open
In uncertain environments, intelligent decision-makers exploit actions that have been rewarding in the past, but also explore actions that could be even better. Several neuromodulatory systems are implicated in exploration, based, in part,…
View article: Intrinsic timescales in the visual cortex change with selective attention and reflect spatial connectivity
Intrinsic timescales in the visual cortex change with selective attention and reflect spatial connectivity Open
Intrinsic timescales characterize dynamics of endogenous fluctuations in neural activity. Variation of intrinsic timescales across the neocortex reflects functional specialization of cortical areas, but less is known about how intrinsic ti…
View article: Large-scale high-density brain-wide neural recording in nonhuman primates
Large-scale high-density brain-wide neural recording in nonhuman primates Open
High-density, integrated silicon electrodes have begun to transform systems neuroscience, by enabling large-scale neural population recordings with single cell resolution. Existing technologies, however, have provided limited functionality…
View article: Functional interactions among neurons within single columns of macaque V1
Functional interactions among neurons within single columns of macaque V1 Open
Recent developments in high-density neurophysiological tools now make it possible to record from hundreds of single neurons within local, highly interconnected neural networks. Among the many advantages of such recordings is that they dram…
View article: Functional Connections Among Neurons within Single Columns of Macaque V1
Functional Connections Among Neurons within Single Columns of Macaque V1 Open
Recent developments in high-density neurophysiological tools now make it possible to record from hundreds of single neurons within local, highly interconnected neural networks. Among the many advantages of such recordings is that they dram…
View article: Rapid Selectivity to Natural Images Across Layers of Primate V1
Rapid Selectivity to Natural Images Across Layers of Primate V1 Open
Visual systems are thought to have adapted to the statistical properties of natural scenes. However, the extent to which visual neurons respond selectively to natural images, and the stage at which that selectivity emerges remains unclear.…