Titilola Aderonke Samuel
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View article: Bacterial communities associated with solid waste leachates (SWL) at Olusosun and Oke-Afa dumpsites in Lagos State, Nigeria
Bacterial communities associated with solid waste leachates (SWL) at Olusosun and Oke-Afa dumpsites in Lagos State, Nigeria Open
Here, we use 16S rRNA gene sequencing to investigate bacterial community profiles at Olusosun and Oke-Afa dumpsites. The Olusosun and Oke-Afa dumpsites had 305 and 306 operational taxonomic units (OTUs) detected, respectively, while the Ol…
View article: Giant Unicystic Ameloblastoma in a Teenager of Azande Tribe: A Clinical Case Report
Giant Unicystic Ameloblastoma in a Teenager of Azande Tribe: A Clinical Case Report Open
Ameloblastoma, a locally aggressive benign odontogenic tumor, represents about 1% of jaw tumors. While typically affecting adults aged 30-60, this case highlights its occurrence in a 17-year-old. Incidence varies globally, with lower rates…
View article: 16S rRNA amplicon sequencing of bacterial communities in Solid Waste Leachates (SWL) from Olusosun Dumpsite, Ojota, Lagos State, Nigeria
16S rRNA amplicon sequencing of bacterial communities in Solid Waste Leachates (SWL) from Olusosun Dumpsite, Ojota, Lagos State, Nigeria Open
Here, we use 16S rRNA gene sequencing to identify bacterial community structure of solid waste leachates from Olusosun dumpsite. Acidobacteria (14.65 %) was the most abundant phylum with clear affiliations. This was followed by Planctomyce…
View article: PVAR Analysis of Environmental Pollution, Health Expenditure and Economic Growth: Evidence from Sub –Saharan Africa
PVAR Analysis of Environmental Pollution, Health Expenditure and Economic Growth: Evidence from Sub –Saharan Africa Open
This study broadly examined the relationship among the environmental pollution, health expenditure and economic growth in SSA using data spanning from 1986 to 2020. The data for this study was secondary in nature and they were sourced from…
View article: Antiproliferative activity of Hoslundia opposita leaf extract and fractions against a human glioblastoma cell line (U251)
Antiproliferative activity of Hoslundia opposita leaf extract and fractions against a human glioblastoma cell line (U251) Open
BACKGROUND: The ineffectiveness of many known anticancer agents for treating several cancer types, especially glioblastoma (GMB), which affects the body's central nervous system, is highly important. GBM is highly invasive and recalcitrant…
View article: Unveiling genome sequence of <i>Bacillus safensis</i> strain WOB7 KX774196, a linamarin-utilizing bacterium (LUB) isolated from cassava wastewater (CWW) in Lagos State, Nigeria
Unveiling genome sequence of <i>Bacillus safensis</i> strain WOB7 KX774196, a linamarin-utilizing bacterium (LUB) isolated from cassava wastewater (CWW) in Lagos State, Nigeria Open
Bacillus safensis strain WOB7 is a linamarin-utilizing bacterium (LUB) that was isolated from cassava wastewater obtained from a processing factory. We present here the draft genome sequence of the strain (WOB7). These data provide valuabl…
View article: Draft genome sequence of <i>Bacillus safensis</i> strain WOIS2 KX774194, a nitrile-metabolizing bacterium isolated from solid waste leachates at Olusosun dumpsite, Ojota, Lagos State, Nigeria
Draft genome sequence of <i>Bacillus safensis</i> strain WOIS2 KX774194, a nitrile-metabolizing bacterium isolated from solid waste leachates at Olusosun dumpsite, Ojota, Lagos State, Nigeria Open
Bacillus safensis strain WOIS2, a nitrile-metabolizing bacterium, was isolated from solid waste leachates at the Olusosun dumpsite, Ojota, Lagos State, Nigeria. Here, we present the draft genome sequence of strain WOIS2. These data provide…
View article: Chemotherapy-induced Electrolyte Disorder and Nephrotoxicity in Cancer Patients from Selected Nigerian Tertiary Health Care Hospitals.
Chemotherapy-induced Electrolyte Disorder and Nephrotoxicity in Cancer Patients from Selected Nigerian Tertiary Health Care Hospitals. Open
Background: Chemotherapy is an important treatment modality widely employed for cancer management. The study investigated nephrotoxicity and electrolytes disorders induced by chemotherapy in cancer patients undergoing chemotherapy in selec…
View article: Health Risk Assessment of Heavy and Trace Metals in Personal Care Products in Nigeria
Health Risk Assessment of Heavy and Trace Metals in Personal Care Products in Nigeria Open
Heavy metal poisoning is linked to disorders like cancer, endocrine disruption, and kidney dysfunction due to prolonged exposure to environmental pollutants. This study assesses heavy and trace metal levels in cosmetic products sold in Nig…
View article: Interplay of Serum Apoptotic Proteins and Oxidative Stress Markers in Prostate Cancer and Benign Prostate Hyperplasia.
Interplay of Serum Apoptotic Proteins and Oxidative Stress Markers in Prostate Cancer and Benign Prostate Hyperplasia. Open
Background Apoptotic evasion is one of the genuine hallmarks of cancer and appears to be a critical component of most therapeutic options in prostate cancer treatment. Reactive oxygen and nitrogen species play a critical role in the execut…
View article: Current Evidence for the Involvement of Hypogonadism and Modulation of Steroid Receptors in Prostate Carcinoma
Current Evidence for the Involvement of Hypogonadism and Modulation of Steroid Receptors in Prostate Carcinoma Open
Prostate cancer (PCa) is the most prevalent cancer in the Nigerian male population, similar to other black populations. It is postulated that exposure to endogenous or environmental steroids prompts prostatic mediated changes via steroid r…
View article: PMON245 Clinical Phenotypes of Polycystic Ovary Syndrome (PCOS) in Nigerian Women: Preliminary Results of the Nigeria PCOS Epidemiology & Phenotype (Nigeria-Pep) Study
PMON245 Clinical Phenotypes of Polycystic Ovary Syndrome (PCOS) in Nigerian Women: Preliminary Results of the Nigeria PCOS Epidemiology & Phenotype (Nigeria-Pep) Study Open
Background Although the phenotype of polycystic ovary syndrome (PCOS) is heterogeneous, there is paucity of data on the prevalence and phenotype of PCOS in sub-Saharan Africa. Methods We studied 75 consecutive consenting women, aged 18-45 …
View article: Diagnostic potential value of circulating PCA3 mRNA in plasma and urine of prostate cancer patients
Diagnostic potential value of circulating PCA3 mRNA in plasma and urine of prostate cancer patients Open
Current reports show that most of the routinely available prostate specific antigen (PSA) derived biomarkers of prostate cancer (PCa) have failed to demonstrate sufficient sensitivity and specificity in clinical use for diagnosis and progn…
View article: Contraceptive Use among Women Assessing Family Planning Services in Different Levels of Health Care Facilities: A Decades Retrospective Review
Contraceptive Use among Women Assessing Family Planning Services in Different Levels of Health Care Facilities: A Decades Retrospective Review Open
Background: Nigeria's population continues to grow at a fast rate despite the presumed increase in the use of contraceptives.Appropriate strategies and policies that will contribute to better coverage may arise from reviewing current trend…
View article: Nitrilase gene detection and nitrile metabolism in two bacterial strains associated with waste streams in Lagos, Nigeria
Nitrilase gene detection and nitrile metabolism in two bacterial strains associated with waste streams in Lagos, Nigeria Open
Background The use of nitrile compounds is usually high, particularly in chemical industries, which calls for serious concern because of their relevance to the environment. The essential role of nitrilases in the bioremediation of harmful …
View article: Metabolic Syndrome Associated with Polycystic Ovary Syndrome in Some Nigerian Women
Metabolic Syndrome Associated with Polycystic Ovary Syndrome in Some Nigerian Women Open
Background: Polycystic Ovary Syndrome (PCOS) is a group of symptoms associated with endocrine disorders in women of reproductive age. Women with this syndrome is at increased risk of metabolic syndrome. This study described the metabolic s…
View article: Descriptor-Free QSAR: Effectiveness and Screening for Putative Inhibitors of FGFR1
Descriptor-Free QSAR: Effectiveness and Screening for Putative Inhibitors of FGFR1 Open
The effectiveness of descriptors-utilizing quantitative structure-activity relationship models in drug design remains limited by the quality of descriptors used in training, this then raises the question: can QSAR models be directly traine…
View article: In vitro antidiabetic potentials, antioxidant activities and phytochemical profile of african black pepper (Piper guineense)
In vitro antidiabetic potentials, antioxidant activities and phytochemical profile of african black pepper (Piper guineense) Open
Background Diabetes mellitus is a metabolic disorder of glucose metabolism and management of blood glucose level is the hallmark in the treatment of this disease. The present study investigated chemical composition, in vitro antioxidant an…
View article: Aberrant effect of genistein on placenta development expressed through alteration in transforming growth factor-β1 and alkaline phosphatase across the maternal serum, the placenta and the amniotic fluid.
Aberrant effect of genistein on placenta development expressed through alteration in transforming growth factor-β1 and alkaline phosphatase across the maternal serum, the placenta and the amniotic fluid. Open
Genistein aberrant effect on fetal development was via its adverse effect on TGCs proliferation and TGf-β1 activities in the placenta tissue.
View article: COVID-19 rapid diagnostic test could contain transmission in low- and middle-income countries
COVID-19 rapid diagnostic test could contain transmission in low- and middle-income countries Open
We found reports of high sensitivity and specificity among the developed RDTs that could complement RT-PCR for the detection of SARS-CoV-2 antibodies, especially for screening in LMICs. However, it is necessary to validate these kits local…
View article: Cassava Wastewater and Solid Waste Leachate as Cyanogenic Substrates for the Growth of Nitrile and Linamarin-Utilizing Bacteria
Cassava Wastewater and Solid Waste Leachate as Cyanogenic Substrates for the Growth of Nitrile and Linamarin-Utilizing Bacteria Open
The direct discharge of wastewaters containing cyanogenic compounds poses severe health hazards, hence this study aimed to establish the biodegradative potential of nitrile and linamarin utilizing bacterial strains in the degradation of cy…