Tobechukwu Okobi
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View article: Comparative Effectiveness of Management Strategies for Stage IV Prostate Cancer: A Narrative Review
Comparative Effectiveness of Management Strategies for Stage IV Prostate Cancer: A Narrative Review Open
Stage IV prostate cancer (PCa) refers to a disease that has metastasized beyond the prostate gland to distant sites, such as bones, visceral organs, or non-regional lymph nodes. While early attempts at curative therapy were occasionally ma…
View article: Pilot Trial of Streamlined Genetic Education and Traceback Genetic Testing in Prostate Cancer Survivors
Pilot Trial of Streamlined Genetic Education and Traceback Genetic Testing in Prostate Cancer Survivors Open
Background: Germline genetic testing is recommended for men with metastatic or high-risk prostate cancer to inform treatment and risk management for other cancers and inform genetic testing in at-risk relatives. However, relatively few pat…
View article: Overview of Beta-Thalassemia
Overview of Beta-Thalassemia Open
Beta-thalassemias are a group of hereditary blood disorders characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic individuals. Th…
View article: Hemophagocytic Lymphohistiocytosis and Hodgkin Lymphoma in a Newly Diagnosed HIV Patient: A Diagnostic Dilemma
Hemophagocytic Lymphohistiocytosis and Hodgkin Lymphoma in a Newly Diagnosed HIV Patient: A Diagnostic Dilemma Open
View article: Immune Checkpoint Inhibitors as a Treatment Option for Bladder Cancer: Current Evidence
Immune Checkpoint Inhibitors as a Treatment Option for Bladder Cancer: Current Evidence Open
View article: Approaches to Smoking Cessation
Approaches to Smoking Cessation Open
Smoking cessation is a critical public health issue. Smoking cessation techniques are essential in reducing the burden of tobacco-related diseases and deaths. Medical practitioners have the potential to assist patients in quitting smoking,…
View article: COVID-19-Induced Myopathy and Diaphragmatic Weakness: A Case Report
COVID-19-Induced Myopathy and Diaphragmatic Weakness: A Case Report Open
Coronavirus disease 2019 (COVID-19) is a respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that can induce myopathy, which can evolve into potentially life-threatening muscle weakness, inc…
View article: Thalassemia Syndromes - New Insights and Transfusion Modalities
Thalassemia Syndromes - New Insights and Transfusion Modalities Open
The thalassemia syndromes are a diverse group of hereditary anemias caused by decreased or absent production of one type of globin chain. Genetic counseling, prenatal diagnosis, and newborn screening are all issues of importance in these i…
View article: Austrian Syndrome: The Forgotten Triad of a Complex Condition in an Antibiotic Era
Austrian Syndrome: The Forgotten Triad of a Complex Condition in an Antibiotic Era Open
[This corrects the article DOI: 10.7759/cureus.32106.].
View article: Screening Asymptomatic Men for Prostate Cancer Using Prostate-Specific Antigen as An Early Detection Tool: A Review of Existing Literature
Screening Asymptomatic Men for Prostate Cancer Using Prostate-Specific Antigen as An Early Detection Tool: A Review of Existing Literature Open
Prostate cancer remains the most common non-skin cancer in men. Prostate-specific antigen (PSA) is recognized as a biomarker for the diagnosis, monitoring, and risk prediction of prostate cancer. However, its role in prostate cancer screen…
View article: Presentation of Colorectal Carcinoma as Abdominal Wall Phlegmon
Presentation of Colorectal Carcinoma as Abdominal Wall Phlegmon Open
Colorectal cancer (CRC) is the third most common malignancy and the second most common deadly cancer worldwide as of 2020. Unusual presentation of this cancer with locally advanced disease is rare and seen in only 5% to 22% of cases. We pr…
View article: High-Fat Diet as a Risk Factor for Breast Cancer: A Meta-Analysis
High-Fat Diet as a Risk Factor for Breast Cancer: A Meta-Analysis Open
High-fat diets have been identified as a major cause of obesity and a potential risk factor for breast cancer. Fat tissue, also known as adipose tissue, produces an excess of estrogen, which has been linked to an increased risk of breast c…
View article: Austrian Syndrome: The Forgotten Triad of a Complex Condition in an Antibiotic Era
Austrian Syndrome: The Forgotten Triad of a Complex Condition in an Antibiotic Era Open
Osler's triad, an alternative term for Austrian syndrome, has a complex pathology comprising of pneumonia, meningitis, and endocarditis, all of which are caused by the hematogenous dissemination of Streptococcus pneumoniae. It can a…
View article: The Evolution of Hypertension Guidelines Over the Last 20+ Years: A Comprehensive Review
The Evolution of Hypertension Guidelines Over the Last 20+ Years: A Comprehensive Review Open
View article: Apical lung mass—A rare presentation of multiple myeloma
Apical lung mass—A rare presentation of multiple myeloma Open
View article: A Review of Four Practice Guidelines of Inflammatory Bowel Disease
A Review of Four Practice Guidelines of Inflammatory Bowel Disease Open
Inflammatory bowel disease (IBD) is a term that encompasses conditions characterized by chronic inflammation of the gastrointestinal tract (GIT). It includes Crohn's disease and ulcerative colitis. Major scientific organizations interested…
View article: The Burden of Obesity in the Rural Adult Population of America
The Burden of Obesity in the Rural Adult Population of America Open
There is an epidemic of obesity in adults in rural America. It is estimated that about 19% of the population resides in rural areas, which encompasses 97% of America's total landmass. Although rural America makes up a fraction of America's…
View article: A Review of Remdesivir Use in End Stage Renal Disease (ESRD)
A Review of Remdesivir Use in End Stage Renal Disease (ESRD) Open
The novel coronavirus disease 2019 (COVID-19) spread quickly worldwide following the first report of pneumonia of unknown cause in Wuhan, China. Since then, the incidence and mortality have continued to rise, with over 120 million cases of…
View article: Effects of Duration of Exposure on Biochemical and Haematological Profile in Liquefied Petroleum Gas (LPG) Plant Workers
Effects of Duration of Exposure on Biochemical and Haematological Profile in Liquefied Petroleum Gas (LPG) Plant Workers Open
Liquefied Petroleum Gas (LPG) plant workers are exposed to a number of hydrocarbons from handling petroleum and petroleum-based products and this exposure poses a major health challenge to these workers. This study was designed to evaluate…