Explanipedia

The sodium-glucose cotransporter-2 inhibitor canagliflozin alleviates endothelial dysfunction in a rat bypass model Open

Ming Ma, Shuo Lian, Patricia Kraft, Tobias Mayer, Alex Ali Sayour , et al. · 2025

Ischemia/reperfusion (IR) injury during coronary artery bypass grafting surgery has detrimental impacts on endothelial integrity and function. Studies have suggested that canagliflozin (CANA) mitigates the risk of cardiovascular events, in…

Alpha‐Synuclein as a Potential Biomarker for Inclusion Body Myositis in Blood and Muscle Open

Tobias Mayer, Leila Motlagh Scholle, Laurie Foerster, Ilka Schneider, Gisela Stoltenburg‐Didinger , et al. · 2025

Aims Diagnosis of inclusion body myositis (IBM) is difficult and currently based on a combination of clinical and (immuno)histological findings. Biomarkers facilitating the diagnostic process are needed. Alpha‐synuclein (αSN) aggregates ar…

Serum chitotriosidase-1 (CHIT1) as candidate biomarker for mitochondriopathies Open

Laurie Foerster, Leila Motlagh Scholle, Tobias Mayer, Ilka Schneider, Gisela Stoltenburg‐Didinger , et al. · 2025

Background Neuromuscular diseases (NMDs) and mitochondriopathies are rare and heterogeneous disorders. Diagnosis is often difficult and delayed, partly due to the lack of reliable biomarkers. Chitotriosidase (CHIT1) as a candidate marker f…

Ein Beitrag zur Bewertung der Leistung dezentraler Materialflusssteuerungssysteme am Beispiel eines Steuerungsprototyps Open

Tobias Mayer, Sergey Libert, Michael ten Hompel · 2024

Das Steuerungsparadigma Internet der Dinge in der Intralogistik propagiert hoch modulare und flexible dezentrale Steuerungssysteme auf Basis von RFID-Technologie und Softwareagenten. Ein produktiver Einsatz solcher Systeme verlangt die Erf…

Anonymous voting using distributed ledger-assisted secure multi-party computation Open

Maximilian Schiedermeier, Omar Hasan, Tobias Mayer, Lionel Brunie, Harald Kosch · 2024

High voter turnout in elections and referendums is desirable to ensure a robust democracy. Secure electronic voting is a vision for the future of elections and referendums. Such a system can counteract factors hindering strong voter turnou…

#2810 Exploring non-renal vasculature: therapeutic implications of proton pump inhibitor and anthelmintic treatment in PCK rat model Open

Jana Heigwer, Tilmann Clanget, Kim Bierhoff, Tobias Mayer, Patricia Kraft , et al. · 2024

Background and Aims Cystic kidney diseases represent ciliopathies that can cause vascular damage through renal hypertension. Additionally, there is growing experimental evidence of endothelial cell abnormalities associated with ciliary pro…

Predicting Client Emotions and Therapist Interventions in Psychotherapy Dialogues Open

Tobias Mayer, Neha Warikoo, Amir Eliassaf, Dana Atzil–Slonim, Iryna Gurevych · 2024

#6189 PRECLINICAL VALIDATION OF REPURPOSABLE CANDIDATE DRUG COMPOUNDS FOR CYSTIC NEPHROPATHIES Open

Tilmann Clanget, Jana Heigwer, Gunjan Pandey, Patricia Kraft, Barbara Rodenbeck , et al. · 2023

Background and Aims Early-onset cystic kidney disease is a clinically and genetically heterogeneous and overlapping group of rare and often severe disorders with limited, mostly symptomatic treatment options. We developed and utilized inhe…

#3357 MORPHOMETRIC AND FUNCTIONAL EVALUATION OF A NON-RENAL VASCULATURE IN FEMALE AND MALE PKD/MHM (CY/+) RATS Open

Baoer Liu, Tobias Mayer, Patricia Kraft, Jana Heigwer, Tilmann Clanget , et al. · 2023

Background and Aims Polycystic kidney disease (PKD) is a cystic genetic disorder of the kidneys. Vascular abnormalities are the most important non-cystic complications in PKD. In the present study, we evaluated aortic morphometry and vascu…

GDPR Compliant Collection of Therapist-Patient-Dialogues Open

Tobias Mayer, Neha Warikoo, O. Grimm, Andreas Reif, Iryna Gurevych · 2022

According to the Global Burden of Disease list provided by the World Health Organization (WHO), mental disorders are among the most debilitating disorders.To improve the diagnosis and the therapy effectiveness in recent years, researchers …

NLP meets psychotherapy: Using predicted client emotions and self-reported client emotions to measure emotional coherence Open

Neha Warikoo, Tobias Mayer, Dana Atzil–Slonim, Amir Eliassaf, Shira Haimovitz , et al. · 2022

Emotions are experienced and expressed through various response systems. Coherence between emotional experience and emotional expression is considered important to clients' well being. To date, emotional coherence (EC) has been studied at …

ACTA 2.0: A Modular Architecture for Multi-Layer Argumentative Analysis of Clinical Trials Open

Benjamin Molinet, Santiago Marro, Elena Cabrio, Serena Villata, Tobias Mayer · 2022

International audience

Bread crust extract protects rats’ vascular grafts from in vitro ischemia/reperfusion injury Open

Sevil Korkmaz‐Icöz, Marcel Schwär, Sivakkanan Loganathan, Kristin Wächter, Adrian‐Iustin Georgevici , et al. · 2022

Ischemia/reperfusion (IR) injury affects harvested vascular grafts during coronary artery bypass surgery. We hypothesized that bread crust extract (BCE) protects vascular grafts from IR injury. Thoracic aortic rings from Wistar rats were m…

ACTA 2.0: A Modular Architecture for Multi-Layer Argumentative Analysis of Clinical Trials Open

Benjamin Molinet, Santiago Marro, Elena Cabrio, Serena Villata, Tobias Mayer · 2022

Evidence-based medicine aims at making decisions about the care of individual patients based on the explicit use of the best available evidence in the patient clinical history and the medical literature results. Argumentation represents a …

Covid-on-the-Web: Graphe de Connaissances et Services pour faire Progresser la Recherche sur la COVID-19 Open

Franck Michel, Fabien Gandon, Valentin Ah-Kane, Anna Bobasheva, Elena Cabrio , et al. · 2021

National audience

Enhancing evidence-based medicine with natural language argumentative analysis of clinical trials Open

Tobias Mayer, Santiago Marro, Elena Cabrio, Serena Villata · 2021

Extraction d’arguments basée sur les transformateurs pour des applications dans le domaine de la santé Open

Tobias Mayer, Elena Cabrio, Serena Villata · 2021

International audience

Vascular reactivity in old spontaneously hypertensive stroke-prone rats- effects of in vitro ischemia/reperfusion injury Open

Sevil Korkmaz‐Icöz, Mona Isabella Benker, Shiliang Li, Sivakkanan Loganathan, Patricia Kraft , et al. · 2021

Objectives: Peripheral arterial disease affects mainly the aorta and lower extremities and commonly results in tissue ischemia. Medical interventions to restore blood flow can induce reperfusion injury. We investigated the effects of both …

Covid-on-the-Web: Exploring the COVID-19 scientific literature through visualization of linked data from entity and argument mining Open

Aline Menin, Franck Michel, Fabien Gandon, Raphaël Gazzotti, Elena Cabrio , et al. · 2021

The unprecedented mobilization of scientists caused by the COVID-19 pandemic has generated an enormous number of scholarly articles that are impossible for a human being to keep track of and explore without appropriate tool support. In thi…

Generating Adversarial Examples for Topic-dependent Argument Classification Open

Tobias Mayer, Santiago Marro, Elena Cabrio, Serena Villata · 2020

International audience

Transformer-Based Argument Mining for Healthcare Applications Open

Tobias Mayer, Elena Cabrio, Serena Villata · 2020

International audience

Enriching Language Models with Semantics Open

Tobias Mayer · 2020

International audience

Covid-on-the-Web: Knowledge Graph and Services to Advance COVID-19 Research Open

Franck Michel, Fabien Gandon, Valentin Ah-Kane, Anna Bobasheva, Elena Cabrio , et al. · 2020

A Transparent Referendum Protocol with Immutable Proceedings and Verifiable Outcome for Trustless Networks Open

Maximilian Schiedermeier, Omar M. Hassan, Tobias Mayer, Jean‐Marc Pierson, Harald Kosch · 2019

A transparent referendum protocol with immutable proceedings and\n verifiable outcome for trustless networks Open

Maximilian Schiedermeier, Omar Hasan, Lionel Brunie, Tobias Mayer, Harald Kosch · 2019

High voter turnout in elections and referendums is very desirable in order to\nensure a robust democracy. Secure electronic voting is a vision for the future\nof elections and referendums. Such a system can counteract factors that hinder\n…

Wanted – <i>K</i>β! Open

Michael Bodensteiner, Tobias Mayer · 2019

The Cu-K wavelength ( = 1.39 Å) has been known for a very long time, mostly as result of an unsuccessful alignment of the diffractometer optics.However, there are benefits and powerful features of this radiation that many crystallographers…

ACTA: A Tool for Argumentative Clinical Trial Analysis Open

Tobias Mayer, Elena Cabrio, Serena Villata · 2019

International audience

ACTA A Tool for Argumentative Clinical Trial Analysis Open

Tobias Mayer, Elena Cabrio, Serena Villata · 2019

Argumentative analysis of textual documents of various nature (e.g., persuasive essays, online discussion blogs, scientific articles) allows to detect the main argumentative components (i.e., premises and claims) present in the text and to…

Evidence Type Classification in Randomized Controlled Trials Open

Tobias Mayer, Elena Cabrio, Serena Villata · 2018

Randomized Controlled Trials (RCT) are a common type of experimental studies in the medical domain for evidence-based decision making. The ability to automatically extract the arguments proposed therein can be of valuable support for clini…

Argument Mining on Clinical Trials Open

Tobias Mayer, Elena Cabrio, Marco Lippi, Paolo Torroni, Serena Villata · 2018

Argument-based decision making has been employed to support a variety of reasoning tasks over medical knowledge. These include evidence-based justifications of the effects of treatments, the detection of conflicts in the knowledge base, an…

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