Explanipedia

Inflammation awakens dormant cancer cells by modulating the epithelial–mesenchymal phenotypic state Open

Jingwei Zhang, Jingwen Zhang, Longfei Han, Shiyi Wu, Jie Li , et al. · 2025

Biology Medicine

The awakening of dormant disseminated cancer cells appears to be responsible for the clinical relapses of patients whose primary tumors have been successfully cured months and even years earlier. In the present study, we demonstrate that d…

Supplementary Data from IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma Open

Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Yuan Hao, Ela Elyada , et al. · 2023

Medicine Biology

Supplementary Figure legends

Supplementary Table S1 from IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma Open

Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Yuan Hao, Ela Elyada , et al. · 2023

Medicine Biology Computer science

DNA motif analysis

Data from IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma Open

Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Yuan Hao, Ela Elyada , et al. · 2023

Biology Medicine

Pancreatic ductal adenocarcinoma (PDAC) is poorly responsive to therapies and histologically contains a paucity of neoplastic cells embedded within a dense desmoplastic stroma. Within the stroma, cancer-associated fibroblasts (CAF) secrete…

Data from IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma Open

Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Yuan Hao, Ela Elyada , et al. · 2023

Medicine Biology

Pancreatic ductal adenocarcinoma (PDAC) is poorly responsive to therapies and histologically contains a paucity of neoplastic cells embedded within a dense desmoplastic stroma. Within the stroma, cancer-associated fibroblasts (CAF) secrete…

Supplementary Table S1 from IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma Open

Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Yuan Hao, Ela Elyada , et al. · 2023

Medicine Biology

DNA motif analysis

Combined Supplementary Figures from IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma Open

Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Yuan Hao, Ela Elyada , et al. · 2023

Medicine Biology

Supplementary Figures S1-S8

Combined Supplementary Figures from IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma Open

Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Yuan Hao, Ela Elyada , et al. · 2023

Medicine Biology

Supplementary Figures S1-S8

Supplementary Data from IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma Open

Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Yuan Hao, Ela Elyada , et al. · 2023

Medicine Biology

Supplementary Figure legends

Data from Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer Open

Mariano Ponz‐Sarvisé, Vincenzo Corbo, Hervé Tiriac, Dannielle D. Engle, Kristopher K. Frese , et al. · 2023

Biology Medicine Chemistry

Purpose:KRAS is mutated in the majority of pancreatic ductal adenocarcinoma. MAPK and PI3K-AKT are primary KRAS effector pathways, but combined MAPK and PI3K inhibition has not been demonstrated to be clinically effective to date. We explo…

SFigure5 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Biology Chemistry Medicine

SFigure5

Data from Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer Open

Mariano Ponz‐Sarvisé, Vincenzo Corbo, Hervé Tiriac, Dannielle D. Engle, Kristopher K. Frese , et al. · 2023

Biology Medicine Chemistry

Purpose:KRAS is mutated in the majority of pancreatic ductal adenocarcinoma. MAPK and PI3K-AKT are primary KRAS effector pathways, but combined MAPK and PI3K inhibition has not been demonstrated to be clinically effective to date. We explo…

Supplementary Data from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Chemistry Biology Art

Supp Figure legends

Data from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Biology

Purpose:Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease characterized by an extensive fibroinflammatory stroma, which includes abundant cancer-associated fibroblast (CAF) populations. PDAC CAFs are heterogeneous, but the nature…

STable1 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Chemistry Biology Medicine

Table of antibodies.

SFigure3 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Chemistry Biology Medicine

SFigure3

SFigure4 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Biology Medicine Art

SFigure4

STable1 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Biology Medicine Art

Table of antibodies.

Supplementary Data from Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer Open

Mariano Ponz‐Sarvisé, Vincenzo Corbo, Hervé Tiriac, Dannielle D. Engle, Kristopher K. Frese , et al. · 2023

Biology Medicine Computer science

Supplementary Figures 1-3

SFigure2 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Chemistry Biology Medicine

SFigure2

SFigure1 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Chemistry Biology Art

SFigure1

SFigure2 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Biology Chemistry Medicine

SFigure2

Data from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Biology

Purpose:Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease characterized by an extensive fibroinflammatory stroma, which includes abundant cancer-associated fibroblast (CAF) populations. PDAC CAFs are heterogeneous, but the nature…

Supplementary Data from Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer Open

Mariano Ponz‐Sarvisé, Vincenzo Corbo, Hervé Tiriac, Dannielle D. Engle, Kristopher K. Frese , et al. · 2023

Medicine Biology

Supplementary Figures 1-3

SFigure1 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Chemistry Biology Medicine

SFigure1

SFigure4 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Chemistry Biology Medicine

SFigure4

SFigure5 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Chemistry Biology Medicine

SFigure5

Supplementary Data from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Art Biology Medicine

Supp Figure legends

SFigure3 from Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer Open

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard , et al. · 2023

Chemistry Biology Medicine

SFigure3

Tobiloba E. Oni YOU? Author Swipe