Todd Nowlen
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View article: Revisiting the Effect of Udenafil on Exercise Performance in Patients With Fontan Circulation: Results of a Post Hoc Analysis of the FUEL Trial
Revisiting the Effect of Udenafil on Exercise Performance in Patients With Fontan Circulation: Results of a Post Hoc Analysis of the FUEL Trial Open
Background In the FUEL (Fontan Udenafil Exercise Longitudinal) trial, a positive treatment effect was identified for outcomes at the ventilatory anaerobic threshold but not for the primary outcome, oxygen consumption (V o 2 ) at peak exerc…
View article: Methylated Arginine Metabolites as Biomarkers for Clinical Status and Response to Type 5 Phosphodiesterase Inhibition in Patients With Fontan Circulation
Methylated Arginine Metabolites as Biomarkers for Clinical Status and Response to Type 5 Phosphodiesterase Inhibition in Patients With Fontan Circulation Open
Background There is significant interest in NO pathway modulators, specifically type 5 phosphodiesterase inhibitors (PDE5is), to treat patients with a Fontan circulation. Trials, however, have had mixed results. The relationship between th…
View article: ICU Admission Prediction for Patients With Kawasaki Disease or MIS-C Using Machine Learning
ICU Admission Prediction for Patients With Kawasaki Disease or MIS-C Using Machine Learning Open
View article: Adolescent Kawasaki Disease patient with coronary calcifications, severe 4-vessel stenosis, and a normal stress MRI
Adolescent Kawasaki Disease patient with coronary calcifications, severe 4-vessel stenosis, and a normal stress MRI Open
View article: Seasons of Kawasaki Disease during the COVID-19 pandemic
Seasons of Kawasaki Disease during the COVID-19 pandemic Open
The incidence of Kawasaki Disease has a peak in the winter months with a trough in late summer/early fall. Environmental/exposure factors have been associated with a time-varying incidence. These factors were altered during the COVID-19 pa…
View article: Cardiac Biomarkers Aid in Differentiation of Kawasaki Disease from Multisystem Inflammatory Syndrome in Children Associated with COVID-19
Cardiac Biomarkers Aid in Differentiation of Kawasaki Disease from Multisystem Inflammatory Syndrome in Children Associated with COVID-19 Open
View article: Obesity and Outcomes of Kawasaki Disease and COVID-19–Related Multisystem Inflammatory Syndrome in Children
Obesity and Outcomes of Kawasaki Disease and COVID-19–Related Multisystem Inflammatory Syndrome in Children Open
Importance Obesity may affect the clinical course of Kawasaki disease (KD) in children and multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19. Objective To compare the prevalence of obesity and associations with…
View article: The Effect of Udenafil on Heart Rate and Blood Pressure in Adolescents With the Fontan Circulation
The Effect of Udenafil on Heart Rate and Blood Pressure in Adolescents With the Fontan Circulation Open
View article: Cardiac Biomarkers Aid in Differentiation of Kawasaki Disease from Multisystem Inflammatory Syndrome in Children Associated with COVID-19
Cardiac Biomarkers Aid in Differentiation of Kawasaki Disease from Multisystem Inflammatory Syndrome in Children Associated with COVID-19 Open
Background: Kawasaki disease (KD) and Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 show clinical overlap and both lack definitive diagnostic testing, making differentiation challenging. We sought to determ…
View article: Kawasaki Disease in the Time of COVID-19 and MIS-C: The International Kawasaki Disease Registry
Kawasaki Disease in the Time of COVID-19 and MIS-C: The International Kawasaki Disease Registry Open
View article: Table of Contents
Table of Contents Open
View article: Isolated Right Subclavian Artery From the Pulmonary Artery in D-Transposition of the Great Arteries
Isolated Right Subclavian Artery From the Pulmonary Artery in D-Transposition of the Great Arteries Open
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View article: The NHLBI Study on Long-terM OUtcomes after the Multisystem Inflammatory Syndrome In Children (MUSIC): Design and Objectives
The NHLBI Study on Long-terM OUtcomes after the Multisystem Inflammatory Syndrome In Children (MUSIC): Design and Objectives Open
View article: Results of the FUEL Trial
Results of the FUEL Trial Open
Background: The Fontan operation creates a total cavopulmonary connection, a circulation in which the importance of pulmonary vascular resistance is magnified. Over time, this circulation leads to deterioration of cardiovascular efficiency…