Tom D. Green
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View article: Effects of fasting on isolated murine skeletal muscle contractile function during acute hypoxia
Effects of fasting on isolated murine skeletal muscle contractile function during acute hypoxia Open
Stored muscle carbohydrate supply and energetic efficiency constrain muscle functional capacity during exercise and are influenced by common physiological variables (e.g. age, diet, and physical activity level). Whether these constraints a…
View article: Effects of fasting induced carbohydrate depletion on murine ischemic skeletal muscle function
Effects of fasting induced carbohydrate depletion on murine ischemic skeletal muscle function Open
Stored muscle carbohydrate supply and energetic efficiency constrain muscle functional capacity during exercise and are influenced by common physiological variables (e.g. age, diet, and physical activity level). Whether these constraints a…
View article: BAG3 (Bcl-2–Associated Athanogene-3) Coding Variant in Mice Determines Susceptibility to Ischemic Limb Muscle Myopathy by Directing Autophagy
BAG3 (Bcl-2–Associated Athanogene-3) Coding Variant in Mice Determines Susceptibility to Ischemic Limb Muscle Myopathy by Directing Autophagy Open
Background: Critical limb ischemia is a manifestation of peripheral artery disease that carries significant mortality and morbidity risk in humans, although its genetic determinants remain largely unknown. We previously discovered 2 overla…
View article: Diminished force production and mitochondrial respiratory deficits are strain-dependent myopathies of subacute limb ischemia
Diminished force production and mitochondrial respiratory deficits are strain-dependent myopathies of subacute limb ischemia Open
View article: Mitochondrial Regulation of the Muscle Microenvironment in Critical Limb Ischemia
Mitochondrial Regulation of the Muscle Microenvironment in Critical Limb Ischemia Open
Critical limb ischemia (CLI) is the most severe clinical presentation of peripheral arterial disease and manifests as chronic limb pain at rest and/or tissue necrosis. Current clinical interventions are largely ineffective and therapeutic …
View article: Muscle cell derived angiopoietin-1 contributes to both myogenesis and angiogenesis in the ischemic environment
Muscle cell derived angiopoietin-1 contributes to both myogenesis and angiogenesis in the ischemic environment Open
Recent strategies to treat peripheral arterial disease (PAD) have focused on stem cell based therapies, which are believed to result in local secretion of vascular growth factors. Little is known, however, about the role of ischemic endoge…