Tom Stiris
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View article: Impact of low dose nicotine on brain-derived neurotrophic factor after global hypoxia in newborn piglets
Impact of low dose nicotine on brain-derived neurotrophic factor after global hypoxia in newborn piglets Open
Objectives The aim of this study was to assess the effect of low-dose nicotine on the expression of brain-derived neurotrophic factor (BDNF) mRNA, its antisense alternative splice form brain-derived neurotrophic factor antisense (BDNF-AS),…
View article: High dose arachidonic and docosahexaenoic acid in very preterm infants and neurodevelopment at 2 years - A double-blind randomized controlled trial
High dose arachidonic and docosahexaenoic acid in very preterm infants and neurodevelopment at 2 years - A double-blind randomized controlled trial Open
Clinicaltrials.gov ID NCT03555019.
View article: No Short-Term Effect of Low-Dose Nicotine on Inflammation after Global Hypoxia in Newborn Piglets
No Short-Term Effect of Low-Dose Nicotine on Inflammation after Global Hypoxia in Newborn Piglets Open
Introduction: Perinatal asphyxia initiates cytokine release and complement activation with risk of brain damage. We assessed the effect of nicotine on innate immunity and hypothesized that nicotine infusion in a newborn piglet model of asp…
View article: Arachidonic and docosahexaenoic acid supplementation and brain maturation in preterm infants; a double blind RCT
Arachidonic and docosahexaenoic acid supplementation and brain maturation in preterm infants; a double blind RCT Open
gov; ID:NCT03555019.
View article: Lung function in preterm infants at 3 months corrected age after neonatal LC‐PUFA supplementation
Lung function in preterm infants at 3 months corrected age after neonatal LC‐PUFA supplementation Open
Objective To test the hypothesis that long‐chain polyunsaturated fatty acid (LC‐PUFA) supplementation improves lung function at 3 months corrected age (CA) compared with standard treatment in very preterm infants. We also aimed to investig…
View article: Inter-site generalizability of EEG based age prediction algorithms in the preterm infant
Inter-site generalizability of EEG based age prediction algorithms in the preterm infant Open
Objective . To overcome the effects of site differences in EEG-based brain age prediction in preterm infants. Approach . We used a ‘bag of features’ with a combination function estimated using support vector regression (SVR) and feature se…
View article: Supplementary Material for: Combining MRI and Spectral EEG for Assessment of Neurocognitive Outcomes in Preterm Infants
Supplementary Material for: Combining MRI and Spectral EEG for Assessment of Neurocognitive Outcomes in Preterm Infants Open
Introduction: Predicting impairment in preterm children is challenging. Our aim is to explore the association between MRI at term-equivalent age (TEA) and neurocognitive outcomes in late childhood and to assess whether the addition of EEG …
View article: Essential Fatty Acid Supplementation and Early Inflammation in Preterm Infants: Secondary Analysis of a Randomized Clinical Trial
Essential Fatty Acid Supplementation and Early Inflammation in Preterm Infants: Secondary Analysis of a Randomized Clinical Trial Open
Introduction: Postnatal inflammation is associated with increased mortality and adverse outcomes in preterm infants. The essential fatty acids arachidonic acid (ARA) and docosahexaenoic acid (DHA) are precursors of lipid mediators with a k…
View article: Combining MRI and Spectral EEG for Assessment of Neurocognitive Outcomes in Preterm Infants
Combining MRI and Spectral EEG for Assessment of Neurocognitive Outcomes in Preterm Infants Open
Introduction: Predicting impairment in preterm children is challenging. Our aim is to explore the association between MRI at term-equivalent age (TEA) and neurocognitive outcomes in late childhood and to assess whether the addition of EEG …
View article: Supplementary Material for: Essential fatty acid supplementation and early inflammation in preterm infants: Secondary analysis of a randomized clinical trial
Supplementary Material for: Essential fatty acid supplementation and early inflammation in preterm infants: Secondary analysis of a randomized clinical trial Open
Introduction: Postnatal inflammation is associated with increased mortality and adverse outcomes in preterm infants. The essential fatty acids arachidonic acid (ARA) and docosahexaenoic acid (DHA) are precursors of lipid mediators with a k…
View article: Early spectral EEG in preterm infants correlates with neurocognitive outcomes in late childhood
Early spectral EEG in preterm infants correlates with neurocognitive outcomes in late childhood Open
Background Evidence regarding the predictive value of early amplitude-integrated electroencephalography (aEEG)/EEG on neurodevelopmental outcomes at school age and beyond is lacking. We aimed to investigate whether there is an association …
View article: Prenatal exposure to methadone or buprenorphine impairs cognitive performance in young adult rats
Prenatal exposure to methadone or buprenorphine impairs cognitive performance in young adult rats Open
The present findings of long-term cognitive impairments in methadone- and buprenorphine-exposed offspring points to a negative impact of OMT on neurobiological development.
View article: Subclinical Mastitis in a European Multicenter Cohort: Prevalence, Impact on Human Milk (HM) Composition, and Association with Infant HM Intake and Growth
Subclinical Mastitis in a European Multicenter Cohort: Prevalence, Impact on Human Milk (HM) Composition, and Association with Infant HM Intake and Growth Open
Background: Subclinical mastitis (SCM) is an inflammatory condition of the mammary gland. We examined the effects of SCM on human milk (HM) composition, infant growth, and HM intake in a mother–infant cohort from seven European countries. …