Tom Völler
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View article: #27. First-in-human evaluation of safety and dosimetry of 64Cu-LLP2A for PET imaging
#27. First-in-human evaluation of safety and dosimetry of 64Cu-LLP2A for PET imaging Open
View article: First-in-Humans Evaluation of Safety and Dosimetry of<sup>64</sup>Cu-LLP2A for PET Imaging
First-in-Humans Evaluation of Safety and Dosimetry of<sup>64</sup>Cu-LLP2A for PET Imaging Open
There remains an unmet need for molecularly targeted imaging agents for multiple myeloma (MM). The integrin very late antigen 4 (VLA4), is differentially expressed in malignant MM cells and in pathogenic inflammatory microenvironmental cel…
View article: Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation
Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation Open
Autoimmune diseases, such as psoriasis and arthritis, show a patchy distribution of inflammation despite systemic dysregulation of adaptive immunity. Thus, additional tissue-derived signals, such as danger-associated molecular patterns (DA…
View article: PET/MRI of Hypoxic Atherosclerosis Using <sup>64</sup>Cu-ATSM in a Rabbit Model
PET/MRI of Hypoxic Atherosclerosis Using <sup>64</sup>Cu-ATSM in a Rabbit Model Open
The results show that hypoxia is present in this rabbit model of atherosclerosis and suggest that 64Cu-ATSM PET/MR is a potentially promising method for the detection of hypoxic and potentially vulnerable atherosclerotic plaque …
View article: Cyclotron Production of High–Specific Activity <sup>55</sup>Co and In Vivo Evaluation of the Stability of <sup>55</sup>Co Metal-Chelate-Peptide Complexes
Cyclotron Production of High–Specific Activity <sup>55</sup>Co and In Vivo Evaluation of the Stability of <sup>55</sup>Co Metal-Chelate-Peptide Complexes Open
This work describes the production of high–specific activity 55 Co and the evaluation of the stability of 55 Co-metal-chelate-peptide complexes in vivo. 55 Co was produced via the 58 Ni(p,α) 55 Co reaction and purified using anion exchange…
View article: Development and evaluation of a non-peptidic ligand for the molecular imaging of inflammatory processes using S100A9 (MRP14) as a novel target
Development and evaluation of a non-peptidic ligand for the molecular imaging of inflammatory processes using S100A9 (MRP14) as a novel target Open
We describe the development and first evaluation of a novel S100A9 specific molecular imaging probe (Cy5.5-CES271) for optical imaging of local inflammatory activity in vivo .