Tomas Dal Cappello
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View article: Influence of esophageal temperature probe tip placement on core temperature measurement accuracy in cold environments: a randomized crossover trial with implications for cardiac arrest management
Influence of esophageal temperature probe tip placement on core temperature measurement accuracy in cold environments: a randomized crossover trial with implications for cardiac arrest management Open
Proximal misplacement of esophageal probes during cold air exposure results in falsely low and more variable CT readings. This may critically affect triage and treatment, particularly in hypothermic cardiac arrest.
View article: Detection of fluid responsiveness by changes of perfusion index and pleth-variability index during passive leg raising in spontaneously breathing post-surgical patients: a prospective interventional study
Detection of fluid responsiveness by changes of perfusion index and pleth-variability index during passive leg raising in spontaneously breathing post-surgical patients: a prospective interventional study Open
Predicting fluid responsiveness is crucial in treating circulatory failure, as only about half of patients benefit from volume expansion by increasing cardiac output (CO). Dynamic tests like passive leg raising (PLR) are preferred over sta…
View article: Drones reduce the time to defibrillation in a highly visited non-urban area: A randomized simulation-based trial
Drones reduce the time to defibrillation in a highly visited non-urban area: A randomized simulation-based trial Open
The use of drones for automated AED delivery in a non-urban area with physical barriers is feasible and leads to a shorter time to defibrillation. Drone-delivered AEDs also involve a lower workload and perceived physical effort than AED re…
View article: Vital parameter monitoring in harsh environment by the MedSENS in-ear multisensor device
Vital parameter monitoring in harsh environment by the MedSENS in-ear multisensor device Open
Accurate assessment of vital parameters is essential for diagnosis and triage of critically ill patients, but not always feasible in out-of-hospital settings due to the lack of suitable devices. We performed an extensive validation of a no…
View article: Shoulder reduction on the scene: current practice and outcome of the Bavarian Mountain Rescue Service—a prospective observational study
Shoulder reduction on the scene: current practice and outcome of the Bavarian Mountain Rescue Service—a prospective observational study Open
View article: Comparative Effectiveness of an Artificial Air Pocket Device to Delay Asphyxiation in Supine Individuals Critically Buried in Avalanche Debris
Comparative Effectiveness of an Artificial Air Pocket Device to Delay Asphyxiation in Supine Individuals Critically Buried in Avalanche Debris Open
Importance Approximately 70% of individuals critically buried in avalanche debris die within 35 minutes as a result of asphyxial cardiac arrest. An artificial air-pocket device (AAPD) that separates inhaled air from exhaled air may delay t…
View article: Surgical masks and filtering facepiece class 2 respirators (FFP2) have no major physiological effects at rest and during moderate exercise at 3000-m altitude: a randomised controlled trial
Surgical masks and filtering facepiece class 2 respirators (FFP2) have no major physiological effects at rest and during moderate exercise at 3000-m altitude: a randomised controlled trial Open
Background During the COVID-19 pandemic, the use of face masks has been recommended or enforced in several situations; however, their effects on physiological parameters and cognitive performance at high altitude are unknown. Methods Eight…
View article: Occupational Accidents Among Search and Rescue Providers During Mountain Rescue Operations and Training Events
Occupational Accidents Among Search and Rescue Providers During Mountain Rescue Operations and Training Events Open
In this long-term retrospective analysis, we showed that accidents occurred among mountain search and rescue providers both during rescue operations and training events. Given the high prevalence and associated costs, it is of pivotal impo…
View article: Drones reduce the treatment-free interval in search and rescue operations with telemedical support – A randomized controlled trial
Drones reduce the treatment-free interval in search and rescue operations with telemedical support – A randomized controlled trial Open
The successful use of drones in SAR operations leads to a reduction in search time and treatment-free interval of patients in challenging terrain, which could improve outcomes in patients suffering from traumatic injuries, the most commonl…
View article: Changes in body mass, appetite-related hormones, and appetite sensation in women during 4 days of hypobaric hypoxic exposure equivalent to 3,500-m altitude
Changes in body mass, appetite-related hormones, and appetite sensation in women during 4 days of hypobaric hypoxic exposure equivalent to 3,500-m altitude Open
This study investigated the effects of hypoxia on appetite regulation in women while strictly controlling for diet, physical activity, menstrual cycle, and environmental conditions. In young women, 4 days of altitude exposure (3,500 m) dec…
View article: Lifespan and ROS levels in different <i>Drosophila melanogaster</i> strains after 24 h hypoxia exposure
Lifespan and ROS levels in different <i>Drosophila melanogaster</i> strains after 24 h hypoxia exposure Open
During recent decades, model organisms such as Drosophila melanogaster have made it possible to study the effects of different environmental oxygen conditions on lifespan and oxidative stress. However, many studies have often yielded contr…
View article: Effects of Carbon Dioxide and Temperature on the Oxygen-Hemoglobin Dissociation Curve of Human Blood: Implications for Avalanche Victims
Effects of Carbon Dioxide and Temperature on the Oxygen-Hemoglobin Dissociation Curve of Human Blood: Implications for Avalanche Victims Open
Completely avalanche-buried patients are frequently exposed to a combination of hypoxia and hypercapnia with a risk of normothermic cardiac arrest. Patients with a long burial time and an air pocket are exposed to a combination of hypoxia,…
View article: Mechanical cardiopulmonary resuscitation in microgravity and hypergravity conditions: A manikin study during parabolic flight
Mechanical cardiopulmonary resuscitation in microgravity and hypergravity conditions: A manikin study during parabolic flight Open
The use of an ACCD allows continuous delivery of high-quality CC in micro- and hypergravity as experienced in parabolic flight. The decision to bring extra load for a high impact and low likelihood event should be based on specifics of its…
View article: Severe traumatic brain injury and hypotension is a frequent and lethal combination in multiple trauma patients in mountain areas – an analysis of the prospective international Alpine Trauma Registry
Severe traumatic brain injury and hypotension is a frequent and lethal combination in multiple trauma patients in mountain areas – an analysis of the prospective international Alpine Trauma Registry Open
View article: A Prospective Evaluation of the Acute Effects of High Altitude on Cognitive and Physiological Functions in Lowlanders
A Prospective Evaluation of the Acute Effects of High Altitude on Cognitive and Physiological Functions in Lowlanders Open
Cognitive function impairment due to high altitude exposure has been reported with some contradictory results regarding the possible selective cognitive domain involvement. We prospectively evaluated in 36 lowlanders, exposed for 3 consecu…
View article: Effect of Wearing Personal Protective Equipment (PPE) on CPR Quality in Times of the COVID-19 Pandemic—A Simulation, Randomised Crossover Trial
Effect of Wearing Personal Protective Equipment (PPE) on CPR Quality in Times of the COVID-19 Pandemic—A Simulation, Randomised Crossover Trial Open
Cardiopulmonary resuscitation (CPR) is considered an aerosol-generating procedure. Consequently, COVID-19 resuscitation guidelines recommend the use of personal protective equipment (PPE) during resuscitation. In this simulation of randomi…
View article: Effect of Acute Exposure to Altitude on the Quality of Chest Compression‐Only Cardiopulmonary Resuscitation in Helicopter Emergency Medical Services Personnel: A Randomized, Controlled, Single‐Blind Crossover Trial
Effect of Acute Exposure to Altitude on the Quality of Chest Compression‐Only Cardiopulmonary Resuscitation in Helicopter Emergency Medical Services Personnel: A Randomized, Controlled, Single‐Blind Crossover Trial Open
Background Helicopter emergency medical services personnel operating in mountainous terrain are frequently exposed to rapid ascents and provide cardiopulmonary resuscitation (CPR) in the field. The aim of the present trial was to investiga…
View article: Hypoxia and hypercapnia effects on cerebral oxygen saturation in avalanche burial: A pilot human experimental study
Hypoxia and hypercapnia effects on cerebral oxygen saturation in avalanche burial: A pilot human experimental study Open
Our data show that ScO2 determined by NIRS was not always impaired in humans breathing into an artificial air pocket despite decreased oxygen supply and decreased carbon dioxide removal. This may indicate that in medium to low s…
View article: Severe traumatic brain injury and hypotension is a frequent and lethal combination in mountain trauma patients – an analysis of the International Alpine Trauma Registry
Severe traumatic brain injury and hypotension is a frequent and lethal combination in mountain trauma patients – an analysis of the International Alpine Trauma Registry Open
Background: Hypotension is associated with worse outcome in patients with traumatic brain injury (TBI) and maintaining a systolic blood pressure (SBP) ≥110 mmHg is recommended. The aim of this study was to assess the incidence of TBI in pa…
View article: Effects of hypothermia, hypoxia, and hypercapnia on brain oxygenation and hemodynamic parameters during simulated avalanche burial: a porcine study
Effects of hypothermia, hypoxia, and hypercapnia on brain oxygenation and hemodynamic parameters during simulated avalanche burial: a porcine study Open
Avalanche patients who are completely buried but still able to breathe are exposed to hypothermia, hypoxia, and hypercapnia (triple H syndrome). In a porcine model, there was no clinically relevant reduction in cerebral oxygenation during …
View article: Climbing Accidents—Prospective Data Analysis from the International Alpine Trauma Registry and Systematic Review of the Literature
Climbing Accidents—Prospective Data Analysis from the International Alpine Trauma Registry and Systematic Review of the Literature Open
Climbing has become an increasingly popular sport, and the number of accidents is increasing in parallel. We aim at describing the characteristics of climbing accidents leading to severe (multisystem) trauma using data from the Internation…
View article: Venous Pooling in Suspension Syndrome Assessed with Ultrasound
Venous Pooling in Suspension Syndrome Assessed with Ultrasound Open
Introduction Suspension syndrome describes a potentially life-threatening event during passive suspension on a rope. The pathophysiological mechanism is not fully understood; however, the most widespread hypothesis assumes blood pools in t…
View article: Correction to: Suspension syndrome: a potentially fatal vagally mediated circulatory collapse—an experimental randomized crossover trial
Correction to: Suspension syndrome: a potentially fatal vagally mediated circulatory collapse—an experimental randomized crossover trial Open
The original version of this article unfortunately contained a mistake. Information was missing in the acknowledgements section. The correct information is given below.
View article: Suspension syndrome: a potentially fatal vagally mediated circulatory collapse—an experimental randomized crossover trial
Suspension syndrome: a potentially fatal vagally mediated circulatory collapse—an experimental randomized crossover trial Open
Sudden pre-syncope during passive suspension in a harness was observed in 30% of the tests. Blood pools in the veins of the lower legs; however, a vagal mechanism finally leads to loss of consciousness. Time to pre-syncope is unpredictable…
View article: Burial duration, depth and air pocket explain avalanche survival patterns in the Alps
Burial duration, depth and air pocket explain avalanche survival patterns in the Alps Open
An avalanche survival curve is graphical illustration of survival probability of complete avalanche burial as a function of time. The purpose of the study was to calculate the first Austrian avalanche survival curve and update a Swiss curv…
View article: The influence of snow physical properties on humans breathing into an artificial air pocket
The influence of snow physical properties on humans breathing into an artificial air pocket Open
Breathing under snow, e.g. while buried by a snow avalanche, is possible in the presence of an air pocket, but limited in time as hypoxia and hypercapnia rapidly develop. It was suspected that the snow physical properties affect the develo…
View article: The STAR Data Reporting Guidelines for Clinical High Altitude Research
The STAR Data Reporting Guidelines for Clinical High Altitude Research Open
The STAR initiative, using the Delphi method, identified a set of key parameters essential for research and reporting in clinical HA medicine.
View article: Effects of snow properties on humans breathing into an artificial air pocket – an experimental field study
Effects of snow properties on humans breathing into an artificial air pocket – an experimental field study Open
View article: Total Body Water Dynamics Estimated with Bioelectrical Impedance Vector Analysis and B-Type Natriuretic Peptide After Exposure to Hypobaric Hypoxia: A Field Study
Total Body Water Dynamics Estimated with Bioelectrical Impedance Vector Analysis and B-Type Natriuretic Peptide After Exposure to Hypobaric Hypoxia: A Field Study Open
Strapazzon, Giacomo, Matiram Pun, Tomas Dal Cappello, Emily Procter, Piergiorgio Lochner, Hermann Brugger, and Antonio Piccoli. Total body water dynamics estimated with bioelectrical impedance vector analysis and B-type natriuretic peptide…
View article: Oxidative stress response to acute hypobaric hypoxia and its association with indirect measurement of increased intracranial pressure: a field study
Oxidative stress response to acute hypobaric hypoxia and its association with indirect measurement of increased intracranial pressure: a field study Open