Tomasz Blicharski
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View article: Assessment of post-traumatic arthritis and functional outcome in patients treated operatively and non-operatively for distal radius Fractures – a 2-year cohort study
Assessment of post-traumatic arthritis and functional outcome in patients treated operatively and non-operatively for distal radius Fractures – a 2-year cohort study Open
For senior patients, non-operative management should be the first choice for DRF. Pain, though subjectively measured, may indicate early PA development before it shows on RTG. Treatment should be individualized, based on patient needs and …
View article: Clinical expert statement on osteoarthritis: diagnosis and therapeutic choices
Clinical expert statement on osteoarthritis: diagnosis and therapeutic choices Open
Osteoarthritis (OA) is a chronic, progressive disease that affects bones and joint structures. Osteoarthritis is associated with joint pain, cartilage degradation, synovial inflammation, subchondral bone remodeling and osteophyte formation…
View article: Strontium coupling with sulphur in mouse bone apatites
Strontium coupling with sulphur in mouse bone apatites Open
One of the key aspects of new advanced biomaterial development is to understand and design new compositions of selected components. The important idea for bioapatite-based materials is the substitution of Ca by other elements, such as stro…
View article: Comparison of Methods for Short-Segment Posterior Stabilization of Lumbar Spine Fractures and Thoracolumbar Junction
Comparison of Methods for Short-Segment Posterior Stabilization of Lumbar Spine Fractures and Thoracolumbar Junction Open
Background: Thoracolumbar and lumbar spine injuries account for 30–60% of spinal fractures, especially at the thoracolumbar junction. Conservative treatment is recommended for stable fractures without neurological symptoms, but studies sug…
View article: The Ways of Forming and the Erosion/Decay/Aging of Bioapatites in the Context of the Reversibility of Apatites
The Ways of Forming and the Erosion/Decay/Aging of Bioapatites in the Context of the Reversibility of Apatites Open
This study primarily focused on the acid erosion of enamel and dentin. A detailed examination of the X-ray diffraction data proves that the products of the acid-caused decay of enamel belong to the family of isomorphic bioapatites, especia…
View article: Faecal microbiota transplantation associated adverse events
Faecal microbiota transplantation associated adverse events Open
Faecal microbiota transplantation (FMT) aims to restore intestinal microbiota balance with the objective of normalising its composition and achieve therapeutic benefits. The procedure involves the administration of fresh or frozen faecal m…
View article: Challenges of Hip Arthroplasty in a Paretic, Spastic Limb: A Case Study on Managing Femoral Neck Fracture Following Fixation Failure in a Hemiparetic Patient
Challenges of Hip Arthroplasty in a Paretic, Spastic Limb: A Case Study on Managing Femoral Neck Fracture Following Fixation Failure in a Hemiparetic Patient Open
Background: Hip fractures and strokes are prevalent and escalating issues in geriatric healthcare. The absence of standardized surgical protocols for patients with spastic hemiparesis and multiple comorbidities presents a significant medic…
View article: Bruxism in a Child with Trisomy 21 (Down Syndrome)—Case Report
Bruxism in a Child with Trisomy 21 (Down Syndrome)—Case Report Open
Bruxism has been defined in recent years and analyzed in detail as the repetitive activity of the muscles of the masticatory system. Both adults and children experience two different forms of bruxism: daytime and nighttime bruxism. Accordi…
View article: Influence of Various Strontium Formulations (Ranelate, Citrate, and Chloride) on Bone Mineral Density, Morphology, and Microarchitecture: A Comparative Study in an Ovariectomized Female Mouse Model of Osteoporosis
Influence of Various Strontium Formulations (Ranelate, Citrate, and Chloride) on Bone Mineral Density, Morphology, and Microarchitecture: A Comparative Study in an Ovariectomized Female Mouse Model of Osteoporosis Open
Osteoporosis stands out as a prevalent skeletal ailment, prompting exploration into potential treatments, including dietary strontium ion supplements. This study assessed the efficacy of supplementation of three strontium forms—strontium c…
View article: Relationship between Upper Limb Functional Assessment and Clinical Tests of Shoulder Mobility and Posture in Individuals Participating in Recreational Strength Training
Relationship between Upper Limb Functional Assessment and Clinical Tests of Shoulder Mobility and Posture in Individuals Participating in Recreational Strength Training Open
Background: The upper limb is crucial for functioning in everyday life, thus comprehensive assessment is crucial for physically active people to monitor the effect of exercise and prevent injuries. The aim of this study was to analyse the …
View article: Does Chronic Pancreatitis in Growing Pigs Lead to Articular Cartilage Degradation and Alterations in Subchondral Bone?
Does Chronic Pancreatitis in Growing Pigs Lead to Articular Cartilage Degradation and Alterations in Subchondral Bone? Open
Chronic pancreatitis (CP), a progressive inflammatory disease, poses diagnostic challenges due to its initially asymptomatic nature. While CP’s impact on exocrine and endocrine functions is well-recognized, its potential influence on other…
View article: Efficacy and safety of piclidenoson in plaque psoriasis: Results from a randomized phase 3 clinical trial (<scp>COMFORT</scp>‐1)
Efficacy and safety of piclidenoson in plaque psoriasis: Results from a randomized phase 3 clinical trial (<span>COMFORT</span>‐1) Open
Objective A3 adenosine receptor (A3AR) is overexpressed in the skin and peripheral blood mononuclear cells of psoriasis patients. We investigated the efficacy/safety of piclidenoson (CF101), an orally bioavailable A3AR agonist that inhibit…
View article: Contribution to Knowledge on Bioapatites: Does Mg Level Reflect the Organic Matter and Water Contents of Enamel?
Contribution to Knowledge on Bioapatites: Does Mg Level Reflect the Organic Matter and Water Contents of Enamel? Open
The matter constituting the enamels of four types of organisms was studied. The variability of the ions was presented in molar units. It was proven that the changes in water contents of the enamel are significantly positively related to ch…
View article: The Impact of Tannic Acid Consumption on Bone Mineralization
The Impact of Tannic Acid Consumption on Bone Mineralization Open
Tannic acid (TA) is an organic compound belonging to the tannin group. Like other tannins, it has an affinity for endogenous proteins, including digestive enzymes, which can result in the reduced digestibility and absorption of nutrients. …
View article: Knee Cartilage Lesion Management—Current Trends in Clinical Practice
Knee Cartilage Lesion Management—Current Trends in Clinical Practice Open
Many patients, particularly those aged above 40, experience knee joint pain, which hampers both sports activities and daily living. Treating isolated chondral and osteochondral defects in the knee poses a significant clinical challenge, pa…
View article: Antioxidant and Cytotoxic Potential of Carlina vulgaris Extract and Bioactivity-Guided Isolation of Cytotoxic Components
Antioxidant and Cytotoxic Potential of Carlina vulgaris Extract and Bioactivity-Guided Isolation of Cytotoxic Components Open
Carlina vulgaris is a poorly understood plant in the context of biological activity, despite its widespread application in ethnomedicine in numerous European countries. The aim of this study was to assess the cytotoxic potential of the pla…
View article: Quantitative Description of Isomorphism in the Series of Simple Compounds
Quantitative Description of Isomorphism in the Series of Simple Compounds Open
The introduction of the notion of energy change resulting from the ion exchange in apatites leads to the question: how can some simple isomorphic series be described using the mentioned idea? We concentrated on the simple isomorphic series…
View article: Osteoporosis treatment with denosumab in routine clinical practice in Poland
Osteoporosis treatment with denosumab in routine clinical practice in Poland Open
The article presents detailed sociodemographic and disease-related characteristics of patients who routinely implemented denosumab therapy. Most of them continued denosumab for at least 12 months, with increased BMD T-scores.
View article: Studies on Chemical Composition, Structure and Potential Applications of Keratoisis Corals
Studies on Chemical Composition, Structure and Potential Applications of Keratoisis Corals Open
The chemical composition and structure of bamboo octocoral Keratoisis spp. skeletons were investigated by using: Scanning Electron Microscopy SEM, Raman Microscopy, X-ray Diffraction XRD, Laser Ablation–Inductively Coupled Plasma LA-ICP, a…
View article: Efficacy and Safety of Intra-Articular Cross-Linked Sodium Hyaluronate for the Treatment of Knee Osteoarthritis: A Prospective, Active-Controlled, Randomized, Parallel-Group, Double-Blind, Multicenter Study
Efficacy and Safety of Intra-Articular Cross-Linked Sodium Hyaluronate for the Treatment of Knee Osteoarthritis: A Prospective, Active-Controlled, Randomized, Parallel-Group, Double-Blind, Multicenter Study Open
The safety and efficacy of Hyruan ONE (test product), an intra-articular cross-linked sodium hyaluronate injection, to treat mild-to-moderate knee osteoarthritis was compared with that of Durolane (comparator) in a prospective, active-cont…
View article: Prophylactic Coronoidectomy Approach during Stable Bone Osteosynthesis after Major Cranio-Facial Injury in the Temporal Region with Muscle Contusion—Should It Be Used?
Prophylactic Coronoidectomy Approach during Stable Bone Osteosynthesis after Major Cranio-Facial Injury in the Temporal Region with Muscle Contusion—Should It Be Used? Open
The coronoidectomy approach is a known but still quite underestimated procedure focused on the removal of the coronoid process of the mandible. Most cases related to outer-joint-related factors causing limited mouth opening (LMO) might be …
View article: Guidelines for the diagnosis and management of osteoporosis in Poland. Update 2022
Guidelines for the diagnosis and management of osteoporosis in Poland. Update 2022 Open
Guidelines to provide an update of the previously published Polish recommendations for the management of women and men with osteoporosis have been developed in line with advances in medical knowledge, evidence-based data, and new concepts …
View article: Assessment of the Impact of Physical Activity on the Musculoskeletal System in Early Degenerative Knee Joint Lesions in an Animal Model
Assessment of the Impact of Physical Activity on the Musculoskeletal System in Early Degenerative Knee Joint Lesions in an Animal Model Open
Osteoarthritis (OA) is one of the most prevalent diseases of the osteoarticular system. Progressive destruction of joints is accompanied by development of pathological changes in the muscle tissue, i.e., weakening, atrophy, and remodelling…
View article: Polish version of the Acute Cystitis Symptom Score for patients with acute uncomplicated cystitis
Polish version of the Acute Cystitis Symptom Score for patients with acute uncomplicated cystitis Open
The Polish version of the ACSS has demonstrated benefits for diagnosis and patient-reported outcome assessment. It is objective, fast, and cost-effective, and it may help to easily confirm the accurate diagnosis of AC. The Polish ASCSS can…
View article: Molecular Mechanisms and Clinical Application of Multipotent Stem Cells for Spinal Cord Injury
Molecular Mechanisms and Clinical Application of Multipotent Stem Cells for Spinal Cord Injury Open
Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and psychosocial sequelae. The majority of patients after SCI suffer from permanent disability caused by motor dysfunction, impaired sensation, neuropath…
View article: Measurements of Energetic States Resulting from Ion Exchanges in the Isomorphic Crystals of Apatites and Bioapatites
Measurements of Energetic States Resulting from Ion Exchanges in the Isomorphic Crystals of Apatites and Bioapatites Open
Developments in the field of nanostructures open new ways for designing and manufacturing innovative materials. Here, we focused on new original ways of calculating energy changes during the substitution of foreign ions into the structure …
View article: Blackcurrant (Ribes nigrum L.) Seeds—A Valuable Byproduct for Further Processing
Blackcurrant (Ribes nigrum L.) Seeds—A Valuable Byproduct for Further Processing Open
The rational exploitation of byproducts is important from the point of view of their potential applicability in various fields. In this study, the possibility of further processing of blackcurrant seeds (BCs), which are a byproduct of frui…
View article: Comparison of the Fluoride Ion Release from Composite and Compomer Materials under Varying pH Conditions—Preliminary In Vitro Study
Comparison of the Fluoride Ion Release from Composite and Compomer Materials under Varying pH Conditions—Preliminary In Vitro Study Open
Fluoride prevents the demineralization and supports remineralization of enamel. It is important to maintain a constant low level of fluoride in the oral cavity at all times. Dental restorative materials that are used for this purpose conta…
View article: Hierarchy of Bioapatites
Hierarchy of Bioapatites Open
Apatites are one of the most intensively studied materials for possible biomedical applications. New perspectives of possible application of apatites correspond with the development of nanomaterials and nanocompounds. Here, an effort to sy…
View article: Concentration of Selected Metalloproteinases and Osteocalcin in the Serum and Synovial Fluid of Obese Women with Advanced Knee Osteoarthritis
Concentration of Selected Metalloproteinases and Osteocalcin in the Serum and Synovial Fluid of Obese Women with Advanced Knee Osteoarthritis Open
The aim of the study was to evaluate the levels of selected MMPs (matrix metalloproteinases) and osteocalcin in the serum and synovial fluid of obese women with osteoarthritis and their correlations with clinical status. The studied group …