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View article: Empagliflozin after myocardial infarction with or without diabetes and chronic kidney disease: Insights from EMPACT‐MI
Empagliflozin after myocardial infarction with or without diabetes and chronic kidney disease: Insights from EMPACT‐MI Open
Background In the EMPACT‐MI trial, empagliflozin did not reduce the primary endpoint of all‐cause mortality or hospitalization for heart failure (HHF) following acute myocardial infarction (AMI) but was associated with a risk reduction for…
View article: Percutaneous treatment of left ventricular free wall rupture and severe mitral regurgitation in a two-week myocardial infarction
Percutaneous treatment of left ventricular free wall rupture and severe mitral regurgitation in a two-week myocardial infarction Open
View article: Safety and efficacy of empagliflozin in heart failure among patients with a history of valvular heart disease: Insights from EMPEROR-Pooled
Safety and efficacy of empagliflozin in heart failure among patients with a history of valvular heart disease: Insights from EMPEROR-Pooled Open
We present the first large analysis of SGLT2i (empagliflozin) use in HF patients by history of VHD. Although VHD history was associated with worse outcomes in HF patients, empagliflozin demonstrated consistent safety, efficacy, and patient…
View article: Comparison of Investigator-Reported and Centrally Adjudicated Heart Failure Outcomes in the EMPEROR-Preserved Trial
Comparison of Investigator-Reported and Centrally Adjudicated Heart Failure Outcomes in the EMPEROR-Preserved Trial Open
Investigator adjudication is an alternative to a CEC with similar accuracy and faster event accumulation in HFpEF. The use of granular (SCTI) criteria did not improve trial performance. Our data suggest that a broader definition of an HHF …
View article: Transfemoral Compared to Transapical Transcatheter Aortic Valve Implantation in Chronic Dialysis-Dependent Patients
Transfemoral Compared to Transapical Transcatheter Aortic Valve Implantation in Chronic Dialysis-Dependent Patients Open
Introduction: Patients with end-stage kidney disease (ESRD) represent a high-risk population in terms of both development of and death by cardiovascular diseases. Outcome data of ESRD patients with severe aortic valve stenosis (AS) treated…
View article: Empagliflozin in acute myocardial infarction in patients with and without type 2 diabetes: A pre‐specified analysis of the <scp>EMPACT</scp>‐<scp>MI</scp> trial
Empagliflozin in acute myocardial infarction in patients with and without type 2 diabetes: A pre‐specified analysis of the <span>EMPACT</span>‐<span>MI</span> trial Open
Aims In the EMPACT‐MI trial, empagliflozin reduced heart failure (HF) hospitalizations but not mortality in acute myocardial infarction (MI). Contemporary reports of clinical event rates with and without type 2 diabetes mellitus (T2DM) in …
View article: The Resilience of Polish Doctors and Their Behavioral Patterns in Coping with Work-Related Stress
The Resilience of Polish Doctors and Their Behavioral Patterns in Coping with Work-Related Stress Open
Background/Objective: The aim of this study was to assess stress-coping patterns among Polish doctors, taking into account their degree of resilience and sociodemographic characteristics. Methods: This study involved 832 (100%) Polish phys…
View article: 2024 Update on Cerebral Embolic Protection After Transcatheter Aortic Valve Replacement
2024 Update on Cerebral Embolic Protection After Transcatheter Aortic Valve Replacement Open
Cerebral embolic protection (CEP) during transcatheter aortic valve replacement (TAVR) has emerged as an important tool in reducing stroke risk associated with this intervention. With the recent expansion of TAVR into lower-risk population…
View article: Advances in Cardiac Imaging and Genetic Testing for Diagnosis and Risk Stratification in Cardiomyopathies: 2024 Update
Advances in Cardiac Imaging and Genetic Testing for Diagnosis and Risk Stratification in Cardiomyopathies: 2024 Update Open
Cardiomyopathies represent a diverse group of heart muscle diseases marked by structural and functional abnormalities that are not primarily caused by coronary artery disease. Recent advances in non-invasive imaging techniques, such as ech…
View article: Echocardiographic Assessment of Left Ventricular Function in Three Oncologic Therapeutic Modalities in Women with Breast Cancer: The ONCO-ECHO Multicenter Study
Echocardiographic Assessment of Left Ventricular Function in Three Oncologic Therapeutic Modalities in Women with Breast Cancer: The ONCO-ECHO Multicenter Study Open
Background: Oncological treatment of breast cancer may be associated with adverse effects on myocardial function. Objectives: The objective of this study was to compare the influence of three oncological treatment methods of intervention o…
View article: Empagliflozin after Acute Myocardial Infarction
Empagliflozin after Acute Myocardial Infarction Open
Among patients at increased risk for heart failure after acute myocardial infarction, treatment with empagliflozin did not lead to a significantly lower risk of a first hospitalization for heart failure or death from any cause than placebo…
View article: Effect of Empagliflozin on Heart Failure Outcomes After Acute Myocardial Infarction: Insights From the EMPACT-MI Trial
Effect of Empagliflozin on Heart Failure Outcomes After Acute Myocardial Infarction: Insights From the EMPACT-MI Trial Open
BACKGROUND: Empagliflozin reduces the risk of heart failure (HF) events in patients with type 2 diabetes at high cardiovascular risk, chronic kidney disease, or prevalent HF irrespective of ejection fraction. Whereas the EMPACT-MI trial (E…
View article: Left Ventricular Function, Congestion, and Effect of Empagliflozin on Heart Failure Risk After Myocardial Infarction
Left Ventricular Function, Congestion, and Effect of Empagliflozin on Heart Failure Risk After Myocardial Infarction Open
In patients with AMI, the severity of left ventricular dysfunction and the presence of congestion was associated with worse outcomes. Empagliflozin reduced first and total HF hospitalizations across the range of LVEF with and without conge…
View article: The role of external iliac artery diameter indexed to BSAscore in predicting vascular access complications aftertransfemoral transcatheter aortic valve implantation
The role of external iliac artery diameter indexed to BSAscore in predicting vascular access complications aftertransfemoral transcatheter aortic valve implantation Open
External iliac artery diameter indexed to BSA could be an underestimated indicator of unfavorable outcomes after TF-TAVI, predicting periprocedural access site complications.
View article: VARC-3 defined outcome of valve-in-valve transcatheter aortic valve implantation in stentless compared with stented aortic bioprostheses
VARC-3 defined outcome of valve-in-valve transcatheter aortic valve implantation in stentless compared with stented aortic bioprostheses Open
Background Valve-in-valve (ViV) transcatheter aortic valve implantation (TAVI) is a viable alternative to redo surgery in selected patients with bioprosthetic valve dysfunction. Most ViV-TAVI procedures have been performed in stented biopr…
View article: Accelerometer vs. other activity measures in heart failure with preserved ejection fraction: the VITALITY‐HFpEF trial
Accelerometer vs. other activity measures in heart failure with preserved ejection fraction: the VITALITY‐HFpEF trial Open
Aims The relationship between accelerometry data and changes in Kansas City Cardiomyopathy Questionnaire‐Physical Limitation Score (KCCQ‐PLS) or 6 min walk test (6MWT) is not well understood. Methods and results VITALITY‐HFpEF accelerometr…
View article: Impact of Enterococci vs. Staphylococci Induced Infective Endocarditis after Transcatheter Aortic Valve Implantation
Impact of Enterococci vs. Staphylococci Induced Infective Endocarditis after Transcatheter Aortic Valve Implantation Open
Background: The two most common organisms found in infective endocarditis following transcatheter aortic valve implantation (TAVI-IE) are enterococci (EC-IE) and staphylococci (SC-IE). We aimed to compare clinical characteristics and outco…
View article: Incidence, Clinical Characteristics, and Impact of Absent Echocardiographic Signs in Patients With Infective Endocarditis After Transcatheter Aortic Valve Implantation
Incidence, Clinical Characteristics, and Impact of Absent Echocardiographic Signs in Patients With Infective Endocarditis After Transcatheter Aortic Valve Implantation Open
Background Echocardiography is the primary imaging modality for diagnosis of infective endocarditis (IE) in prosthetic valve endocarditis (PVE) including IE after transcatheter aortic valve implantation (TAVI). This study aimed to evaluate…
View article: Surgical Treatment of Patients With Infective Endocarditis After Transcatheter Aortic Valve Implantation
Surgical Treatment of Patients With Infective Endocarditis After Transcatheter Aortic Valve Implantation Open
View article: High Residual Gradient Following a SelfExpandable Transcatheter Aortic Valve-in-Valve Implantation — Risk Factor Analysis, Outcomes, and Survival
High Residual Gradient Following a SelfExpandable Transcatheter Aortic Valve-in-Valve Implantation — Risk Factor Analysis, Outcomes, and Survival Open
High residual transvalvular gradient after TAVI-ViV is not rare, but it does not significantly affect mortality. High residual mean gradient has a negative impact on NYHA functional class improvement after the procedure. High preoperative …
View article: Perivalvular Extension of Infective Endocarditis After Transcatheter Aortic Valve Replacement
Perivalvular Extension of Infective Endocarditis After Transcatheter Aortic Valve Replacement Open
Background Infective endocarditis (IE) following transcatheter aortic valve replacement (TAVR) has been associated with a dismal prognosis. However, scarce data exist on IE perivalvular extension (PEE) in such patients. Methods This multic…
View article: Infective Endocarditis Caused by Staphylococcus aureus After Transcatheter Aortic Valve Replacement
Infective Endocarditis Caused by Staphylococcus aureus After Transcatheter Aortic Valve Replacement Open
View article: Prospective multicenter Polish Stress Echocardiography Registry (PolStress-Echopro) – the role in clinical practice
Prospective multicenter Polish Stress Echocardiography Registry (PolStress-Echopro) – the role in clinical practice Open
The most commonly used SE is the DSE. Negative test results allowed in almost half of the patients to resign from invasive coronarography. Stress echocardiography should be more frequently used in patients with VHD in the qualification for…
View article: Direct Percutaneous Mitral Annuloplasty in Patients With Functional Mitral Regurgitation: When and How
Direct Percutaneous Mitral Annuloplasty in Patients With Functional Mitral Regurgitation: When and How Open
Mitral regurgitation (MR) is a frequent valvular disease among patients deemed too high risk for surgery. Echocardiography along with CT is the primary diagnostic tool for MR and offers a comprehensive 3D assessment in patient selection an…
View article: Characterization of Bacteriophage vB-EcoS-95, Isolated From Urban Sewage and Revealing Extremely Rapid Lytic Development
Characterization of Bacteriophage vB-EcoS-95, Isolated From Urban Sewage and Revealing Extremely Rapid Lytic Development Open
Morphological, biological, and genetic characteristics of a virulent Siphoviridae phage, named vB-EcoS-95, is reported. This phage was isolated from urban sewage. It was found to infect some Escherichia coli strains giving cl…
View article: Bad Phages in Good Bacteria: Role of the Mysterious orf63 of λ and Shiga Toxin-Converting Φ24B Bacteriophages
Bad Phages in Good Bacteria: Role of the Mysterious orf63 of λ and Shiga Toxin-Converting Φ24B Bacteriophages Open
Lambdoid bacteriophages form a group of viruses that shares a common schema of genome organization and lifecycle. Some of them can play crucial roles in creating the pathogenic profiles of Escherichia coli strains. For example, Shig…
View article: Aortic valve-in-valve procedures for treatment of failing surgically implanted bioprosthesis
Aortic valve-in-valve procedures for treatment of failing surgically implanted bioprosthesis Open
Trvanlivost biologických chlopní je omezena na dobu 12-20 let. Degenerativní změny na chlopních vedou buď ke vzniku těžké stenózy (na základě kalcifikace nebo trombózy), nebo regurgitace (na základě strukturálních změn chlopenních cípů, in…
View article: Biodiversity of bacteriophages: morphological and biological properties of a large group of phages isolated from urban sewage
Biodiversity of bacteriophages: morphological and biological properties of a large group of phages isolated from urban sewage Open
View article: Oxidative Stress in Shiga Toxin Production by Enterohemorrhagic <i>Escherichia coli</i>
Oxidative Stress in Shiga Toxin Production by Enterohemorrhagic <i>Escherichia coli</i> Open
Virulence of enterohemorrhagic Escherichia coli (EHEC) strains depends on production of Shiga toxins. These toxins are encoded in genomes of lambdoid bacteriophages (Shiga toxin‐converting phages), present in EHEC cells as prophages. The g…
View article: Detection of protozoans Babesia microti and <i>Toxoplasma gondii</i> and their co-existence in ticks (Acari: Ixodida) collected in Tarnogórski district (Upper Silesia, Poland)
Detection of protozoans Babesia microti and <i>Toxoplasma gondii</i> and their co-existence in ticks (Acari: Ixodida) collected in Tarnogórski district (Upper Silesia, Poland) Open
The study showed a high risk of exposure to Bm and Tg in the studied area. Ticks Ir play an important role in the transmission of Bm in this region. Demonstrating a high percentage of ticks collected from animals infected with Tg may indic…