Tommaso Ruelle
YOU?
Author Swipe
View article: Insights on the association of anthropometric and metabolic variables with tumor features and genomic risk in luminal early breast cancer: Results of a multicentric prospective study
Insights on the association of anthropometric and metabolic variables with tumor features and genomic risk in luminal early breast cancer: Results of a multicentric prospective study Open
View article: Adverse events and impact on quality of life of antibody‐drug conjugates in the treatment of metastatic breast cancer: A systematic review and meta‐analysis
Adverse events and impact on quality of life of antibody‐drug conjugates in the treatment of metastatic breast cancer: A systematic review and meta‐analysis Open
Background Antibody‐drug conjugates are novel effective therapies for metastatic breast cancer. Nevertheless, their toxicity profile can significantly affect patients' quality of life over time. Methods This is a systematic review and meta…
View article: Factors associated with first-to-second-line attrition among patients with metastatic breast cancer in the real world
Factors associated with first-to-second-line attrition among patients with metastatic breast cancer in the real world Open
View article: Insights on the Association of Anthropometric and Metabolic Variables with Tumor Features and Genomic Risk in Luminal Early Breast Cancer: Results of a Multicentric Prospective Study
Insights on the Association of Anthropometric and Metabolic Variables with Tumor Features and Genomic Risk in Luminal Early Breast Cancer: Results of a Multicentric Prospective Study Open
View article: Comparison of Suboptimal Versus Adequate Ovarian Function Suppression in Premenopausal Women with Early Breast Cancer Treated with Adjuvant Endocrine Therapy: An Exploratory Analysis of Two Prospective Studies
Comparison of Suboptimal Versus Adequate Ovarian Function Suppression in Premenopausal Women with Early Breast Cancer Treated with Adjuvant Endocrine Therapy: An Exploratory Analysis of Two Prospective Studies Open
View article: The journey of patients affected by metastatic hormone receptor-positive/HER2-negative breast cancer from CDK 4/6 inhibitors to second-line treatment: A real-world analysis of 701 patients enrolled in the GIM14/BIOMETA study
The journey of patients affected by metastatic hormone receptor-positive/HER2-negative breast cancer from CDK 4/6 inhibitors to second-line treatment: A real-world analysis of 701 patients enrolled in the GIM14/BIOMETA study Open
Endocrine therapy plus CDK 4/6i represents an effective treatment, regardless of HER2 status (low/zero). Second-line agents did not differ significantly in terms of TTD. Endocrine resistant cancers exhibit poor response to CDK 4/6i.
View article: Practices and views about palliative care at the end of life: A survey of oncologists from the Italian region of Liguria
Practices and views about palliative care at the end of life: A survey of oncologists from the Italian region of Liguria Open
Introduction: We conducted an online survey to investigate oncologists' clinical practices and views on palliative care at the end of life in the Italian region of Liguria. Methods: The survey included 29 items divided into three sections:…
View article: Clinical Evidence of Methods and Timing of Proper Follow-Up for Head and Neck Cancers
Clinical Evidence of Methods and Timing of Proper Follow-Up for Head and Neck Cancers Open
Background: For patients with head and neck squamous cell carcinoma (HNSCC), after a single or multi-modality treatment, a specific follow-up strategy is needed, but there is no agreement between the main international societies on the pro…
View article: Psychometric properties of patient-reported outcomes Common Terminology Criteria for adverse events (PRO-CTCAE®) in breast cancer patients: The prospective observational multicenter VIP study
Psychometric properties of patient-reported outcomes Common Terminology Criteria for adverse events (PRO-CTCAE®) in breast cancer patients: The prospective observational multicenter VIP study Open
View article: Patterns of care at the end of life: a retrospective study of Italian patients with advanced breast cancer
Patterns of care at the end of life: a retrospective study of Italian patients with advanced breast cancer Open
Objectives To better understand the type of care offered to Italian patients with advanced breast cancer at the End-of-Life (EoL), we conducted a retrospective observational study. EoL was defined as the period of six months before death. …
View article: 290P Adverse events (AEs) and impact on quality of life (QoL) of antibody-drug conjugates (ADC) in the treatment of metastatic breast cancer (mBC): A systematic review and meta-analysis of randomized controlled trials (RCTs)
290P Adverse events (AEs) and impact on quality of life (QoL) of antibody-drug conjugates (ADC) in the treatment of metastatic breast cancer (mBC): A systematic review and meta-analysis of randomized controlled trials (RCTs) Open
ADCs are a novel effective therapy for BC. Several RCTs compared ADCs vs therapy of physician's choice (TPC) showing impressive efficacy and leading to their accelerated approval. However, ADCs' toxicity profile can significantly affect pa…
View article: 210P Prognostic value of HER2-low status in metastatic breast cancer (mbc) patients treated with I line CDK 4/6 inhibitors (CDK 4/6i): A real-word analysis of the GIM14/BIOMETA study
210P Prognostic value of HER2-low status in metastatic breast cancer (mbc) patients treated with I line CDK 4/6 inhibitors (CDK 4/6i): A real-word analysis of the GIM14/BIOMETA study Open
The combination of CDK 4/6i and endocrine treatment is the standard first-line treatment in patients with hormone receptor-positive/HER2-negative mBC. It is still unclear whether HER2-low status has a prognostic impact in this patients' su…
View article: 125P Suboptimal ovarian suppression during adjuvant endocrine therapy for premenopausal women with breast cancer: An exploratory analysis of the PREFER and GIM 23 studies
125P Suboptimal ovarian suppression during adjuvant endocrine therapy for premenopausal women with breast cancer: An exploratory analysis of the PREFER and GIM 23 studies Open
Adjuvant endocrine therapy (ET) with exemestane combined with LHRH analog (LHRHa) is standard of care for premenopausal women with hormone receptor-positive breast cancer. However, LHRHa may not always achieve complete ovarian suppression …
View article: Evolving treatments and outcomes in HER2-Positive metastatic breast cancer: Data from the GIM14/BIOMETA study
Evolving treatments and outcomes in HER2-Positive metastatic breast cancer: Data from the GIM14/BIOMETA study Open
View article: Patterns of care at the end of life: A retrospective study of Italian patients with advanced breast cancer.
Patterns of care at the end of life: A retrospective study of Italian patients with advanced breast cancer. Open
Objectives To better understand the type of care offered to Italian patients with advanced breast cancer at the End-of-Life (EoL), we conducted a retrospective observational study. EoL was defined as the period of six months before death. …
View article: “No Ink on Tumor” in Breast-Conserving Surgery after Neoadjuvant Chemotherapy
“No Ink on Tumor” in Breast-Conserving Surgery after Neoadjuvant Chemotherapy Open
Background/Aim: Patients with Stage I-II breast cancer undergoing breast-conserving surgery after neoadjuvant chemotherapy (BCS-NAC) were retrospectively assessed in order to evaluate the extent of a safe excision margin. Materials and Met…
View article: How to Protect Ovarian Function before and during Chemotherapy?
How to Protect Ovarian Function before and during Chemotherapy? Open
A significant number of women receive a cancer diagnosis before their age of natural menopause. Among these patients, the most frequent neoplasms are breast cancer, gynecological, and hematological malignancies. Premature ovarian insuffici…
View article: The PREgnancy and FERtility (PREFER) Study Investigating the Need for Ovarian Function and/or Fertility Preservation Strategies in Premenopausal Women With Early Breast Cancer
The PREgnancy and FERtility (PREFER) Study Investigating the Need for Ovarian Function and/or Fertility Preservation Strategies in Premenopausal Women With Early Breast Cancer Open
Background Offering ovarian function and/or fertility preservation strategies in premenopausal women with newly diagnosed breast cancer candidates to undergo chemotherapy is standard of care. However, few data are available on uptake and m…
View article: Comparing the Gonadotoxicity of Multiple Breast Cancer Regimens: Important Understanding for Managing Breast Cancer in Pre-Menopausal Women
Comparing the Gonadotoxicity of Multiple Breast Cancer Regimens: Important Understanding for Managing Breast Cancer in Pre-Menopausal Women Open
Over the last several decades, improvements in breast cancer treatment have contributed to increased cure rates for women diagnosed with this malignancy. Consequently, great importance should be paid to the long-term side effects of system…
View article: 1700P Perception and attitudes of Italian physicians towards the management of checkpoint inhibitors in oncology during COVID-19 outbreak: Results from a national survey
1700P Perception and attitudes of Italian physicians towards the management of checkpoint inhibitors in oncology during COVID-19 outbreak: Results from a national survey Open
View article: Italian survey on managing immune checkpoint inhibitors in oncology during COVID‐19 outbreak
Italian survey on managing immune checkpoint inhibitors in oncology during COVID‐19 outbreak Open
Background During COVID‐19 outbreak, oncological care has been reorganized. Patients with cancer have been reported to experience a more severe COVID‐19 syndrome; moreover, there are concerns of a potential interference between immune chec…