Explanipedia

Prognosis, clinicopathological characteristics, and treatment patterns of patients with ER-intermediate-positive breast cancer undergoing long-term follow-up Open

Naoya Matsumoto, Yumi Wanifuchi‐Endo, Takashi Fujita, Tomoko Asano, Mitsuo Terada , et al. · 2025

A Novel Heterozygous and Pathogenic Variant of the <i>HNF1B</i> Gene Associated with Autosomal Dominant Tubulointerstitial Kidney Disease with a Broad Spectrum of Extrarenal Phenotypes Open

Jun‐Ya Kaimori, Jun Matsuda, Asif Jan, Yuki Kawano, Takayuki Kawaoka , et al. · 2025

We encountered a family with hereditary renal failure, renal medullary cysts, pancreatic hypoplasia, hypomagnesemia, liver enzyme abnormalities, and diabetes mellitus (DM). We identified a novel heterozygous variant of HNF1B (NM_000458.4:c…

Characterizing user demographics in posts related to breast, lung and colon cancer on Japanese twitter (X) Open

Maho Kusudo, Mitsuo Terada, Nari Kureyama, Yumi Wanifuchi‐Endo, Takashi Fujita , et al. · 2024

Who Influences Cancer Conversations on Twitter in Japan? Comparison of Breast, Lung, and Colon Cancer-Related Tweets in Japanese Open

Maho Kusudo, Mitsuo MitsuoTerada, Nari Kureyama, Yumi Wanifuchi‐Endo, Takashi Fujita , et al. · 2023

Various cancer-related information is spreading on social media. Our study aimed to examine the account types associated with cancer-related tweets on Twitter in Japan, specifically focusing on breast, lung, and colon cancer. Using the Twi…

Fact-Checking Cancer Information on Social Media in Japan: Retrospective Study Using Twitter Open

Nari Kureyama, Mitsuo Terada, Maho Kusudo, Kazuki Nozawa, Yumi Wanifuchi‐Endo , et al. · 2023

Background The widespread use of social media has made it easier for patients to access cancer information. However, a large amount of misinformation and harmful information that could negatively impact patients’ decision-making is also di…

Fact-Checking Cancer Information on Social Media in Japan: Retrospective Study Using Twitter (Preprint) Open

Nari Kureyama, Mitsuo Terada, Maho Kusudo, Kazuki Nozawa, Yumi Wanifuchi‐Endo , et al. · 2023

BACKGROUND The widespread use of social media has made it easier for patients to access cancer information. However, a large amount of misinformation and harmful information that could negatively impact patients’ decision-making is also d…

Low TINAGL1 expression is a marker for poor prognosis in breast cancer Open

Akiko Kato, Naoto Kondo, Yumi Wanifuchi‐Endo, Takashi Fujita, Tomoko Asano , et al. · 2022

Co-expression effect of LLGL2 and SLC7A5 to predict prognosis in ERα-positive breast cancer Open

Tomoka Hisada, Naoto Kondo, Yumi Wanifuchi‐Endo, Satoshi Osaga, Takashi Fujita , et al. · 2022

Lethal giant larvae homolog 2 (LLGL2) and solute carrier family 7 member 5 (SLC7A5) have been reported to be involved in resistance to endocrine therapy. This study aimed to assess the effects of LLGL2/SLC7A5 co-expression in predicting pr…

Granulocyte colony-stimulating factor-associated aortitis in a woman with breast cancer: a case report Open

Nana Matsumoto, Naoto Kondo, Yumi Wanifuchi‐Endo, Tomoko Asano, Tomoka Hisada , et al. · 2022

Efficacy and impact of SARS-CoV-2 vaccination on cancer treatment for breast cancer patients: a multi-center prospective observational study Open

Mitsuo Terada, Naoto Kondo, Yumi Wanifuchi‐Endo, Takashi Fujita, Tomoko Asano , et al. · 2022

Low TINAGL1 expression is a marker for poor prognosis in breast cancer Open

Akiko Kato, Naoto Kondo, Yumi Wanifuchi‐Endo, Takashi Fujita, Tomoko Asano , et al. · 2022

Purpose: Tubulointerstitial nephritis antigen-like 1 (TINAGL1) was reported to suppress tumor metastasis and growth in triple-negative (TN) breast cancer. We aimed to determine the associations of TINAGL1 expression with clinicopathologica…

Efficacy and impact of SARS-CoV-2 vaccination on cancer treatment for breast cancer patients: A multi-center prospective observational study Open

Mitsuo Terada, Naoto Kondo, Yumi Wanifuchi‐Endo, Takashi Fujita, Tomoko Asano , et al. · 2022

PurposeVaccination is an essential strategy to prevent infection in the SARS-CoV-2 pandemic. However, there are concerns about vaccine efficacy and the impact of vaccination on cancer treatment. Additionally, the emergence of novel variant…

Low HECTD1 mRNA expression is associated with poor prognosis and may be correlated with increased mitochondrial respiratory function in breast cancer Open

Yasuaki Uemoto, Eriko Katsuta, Naoto Kondo, Yumi Wanifuchi‐Endo, Takashi Fujita , et al. · 2022

HECT domain E3 ubiquitin ligase 1 (HECTD1) has been reported to be a negative regulator of epithelial-mesenchymal transition and to decrease breast cancer invasion and metastasis. However, the clinical significance and detailed role of HEC…

Discovering novel mechanisms of taxane resistance in human breast cancer by whole‑exome sequencing Open

Yumi Wanifuchi‐Endo, Naoto Kondo, Yu Dong, Takashi Fujita, Tomoko Asano , et al. · 2021

Taxanes are important drugs used in the treatment of breast cancer; however, some cancer types are taxane-resistant. The aim of the present study was to investigate the underlying mechanisms of taxane resistance using whole-exome sequencin…

Co-expression Effect of LLCL2 and SLC7A5 to Predict Prognosis in ERα-Positive Breast Cancer Open

Tomoka Hisada, Naoto Kondo, Yumi Wanifuchi‐Endo, Satoshi Osaga, Takashi Fujita , et al. · 2021

Lethal giant larvae homolog 2 (LLGL2) and solute carrier family 7 member 5 (SLC7A5) have been reported to be involved in resistance to endocrine therapy. This study aimed to assess the effects of LLGL2/SLC7A5 co-expression in predicting pr…

Prognostic impact of co-expression of LLCL2 and SLC7A5 in ERα-positive breast cancer patients Open

Tomoka Hisada, Naoto Kondo, Yumi Wanifuchi‐Endo, Satoshi Osaga, Takashi Fujita , et al. · 2021

Background Lethal giant larvae homolog 2 (LLGL2) functions as a promoter of tumor growth and localizes at cell junctions and membranes with solute carrier family 7 member 5 (SLC7A5) in estrogen receptor α (ERα)-positive breast cancer. LLGL…

Decreased HECTD1 mRNA expression is associated with poor prognosis and enhanced mitochondrial cellular respiratory function in breast cancer Open

Yasuaki Uemoto, Eriko Katsuta, Naoto Kondo, Yumi Wanifuchi‐Endo, Takashi Fujita , et al. · 2021

HECT domain E3 ubiquitin ligase 1 (HECTD1) has been reported to be a negative regulator of epithelial-mesenchymal transition and to decrease breast cancer invasion and metastasis. However, the clinical significance and detailed role of HEC…

Predictive Factors for Patients who Need Treatment for Chronic Post-Surgical Pain (CPSP) after Breast Cancer Surgery Open

Yasuaki Uemoto, Megumi Uchida, Naoto Kondo, Yumi Wanifuchi‐Endo, Takashi Fujita , et al. · 2021

Purpose: Although chronic postsurgical pain (CPSP) after breast cancer surgery is a common and prevalent postsurgical adverse event, the need for CPSP treatment has not been investigated. This study examined the proportion of patients who …

Sentinel lymph node biopsy may be unnecessary for ductal carcinoma<i>in situ</i>of the breast that is small and diagnosed by preoperative biopsy Open

Yasuaki Uemoto, Naoto Kondo, Yumi Wanifuchi‐Endo, Tomoko Asano, Tomoka Hisada , et al. · 2020

Background Current guidelines do not recommend that sentinel lymph node biopsy is routinely performed for ductal carcinoma in situ; thus, indications for sentinel lymph node biopsy in patients with ductal carcinoma in situ remain controver…

Effects of serum estradiol and progesterone on estrogen-regulated gene expression in breast cancers of premenopausal patients Open

Yumi Wanifuchi‐Endo, Tomoko Asano, Naoto Kondo, Yukari Hato, Yu Dong , et al. · 2018

The serum E2 level on the day of surgery influences estrogen-regulated gene expression moderately in patients found to be strongly positive for estrogen receptor α by immunohistochemistry. Changes in serum E2 levels might influence the res…

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